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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T81356 | PTBP1-RNA-binding inhibitor P6 TFA | PTBP1 α3-helix derived peptide P6 TFA | |
PTBP1-RNA-binding inhibitor P6 (PTBP1 α3-helix derived peptide P6) TFA is a stapled peptide that acts as an inhibitor for the splicing factor PTBP1, targeting the alternative splicing events this protein regulates. It op... | |||
T16766 | Ro 08-2750 | ||
Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor which binds to NGF, and with an IC50 of ~ 1 µM. Ro 08-2750 is a selective MSI RNA-binding activity inhibitor, with an IC50 of 2.7 μM. Ro 08-2... | |||
T83729 | Tat-CIRP TFA | Tat-Cold-inducible RNA Binding Protein | |
Tat-CIRP, a peptide inhibitor, impedes the protein-protein interaction between myeloid differentiation 2 (MD-2), also known as lymphocyte antigen 96 (LY96), and cold-inducible RNA binding protein (CIRP) by binding to MD-... | |||
T6823 | E3330 | HIF/HIF Prolyl-Hydroxylase , DNA/RNA Synthesis | |
E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity. | |||
T1822 | Clemizole | HCV Protease , Histamine Receptor | |
Clemizole is an H1 histamine receptor antagonist, can inhibit NS4B's RNA binding and hepatitis C virus (HCV) replication. | |||
T1822L | Clemizole hydrochloride | HCV Protease , Histamine Receptor | |
Clemizole hydrochloride is an antagonist for H1 histamine receptor. According to the research, Clemizole hydrochloride can inhibit hepatitis C virus (HCV) replication and NS4B's RNA binding. | |||
T27835 | Lin281632 | Lin-28 1632,Lin-281632,Lin 281632,Lin28 1632,Lin 28 163 | |
Lin28 1632 is an inhibitor of RNA binding protein Lin28. It promotes mESC differentiation. Lin281632 is also bromodomain inhibitor. | |||
T40122 | L-Histidine benzyl ester bistosylate | Others | |
L-Histidine benzyl ester bistosylate may serve as an activator for HutP, an RNA-binding protein. | |||
T7330 | Nucleozin | Influenza Virus | |
Nucleozin targets influenza A nucleoprotein (NP), a multifunctional, RNA-binding protein necessary for virus replication. | |||
T9879 | Hydroxystilbamidine | Oxistilbamidinum,(E)-hydroxystilbamidine,2-Hydroxy-4,4'-diguanylstilbene,Bis(8-hydroxyquinolinium) sulphate | Others |
Hydroxystilbamidine ((E)-hydroxystilbamidine), a dye capable of binding to both DNA and RNA, has been found to be a powerful inhibitor of cellular ribonucleases. | |||
T1747 | Tedizolid | TR 700,DA-7157,Torezolid | MAO , Antibacterial , Antibiotic |
Tedizolid (DA-7157)is a novel oxazolidinone-class antibiotic that inhibits bacterial protein synthesis by binding to the 23S ribosomal RNA of the 50S subunit of the ribosome. | |||
T73475 | SMN-C2 | DNA/RNA Synthesis | |
SMN-C2 is a selective regulator of SMN2 gene splicing, a risdiplam analogue, a selective RNA-binding ligand that regulates pre-mRNA splicing and acts by binding to SMN2 pre-mRNA.SMN-C2 has the potential to be used in the... | |||
T2219 | Puromycin dihydrochloride | CL13900 dihydrochloride,Puromycin 2HCl | ribosome , DNA/RNA Synthesis , Antibacterial , Antibiotic |
Puromycin dihydrochloride (CL13900 dihydrochloride) is a cinnamamide adenosine antibiotic and an inhibitor of protein synthesis. Puromycin dihydrochloride inhibits protein synthesis by binding to RNA and has antitumor an... | |||
TNU0091 | 3'-Deoxy-3'-fluoroguanosine | Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis | |
3'-Deoxy-3'-fluoroguanosine is a nucleoside phosphorylase inhibitor that inhibits RNA replication by binding replons. 3 '-Deoxy-3' -fluoroguanosine is used to treat viral hepatitis, cancer and other diseases. | |||
T50026 | Aquacycline | HSV | |
Oxytetracycline (OTC) is a broad-spectrum antibiotic that acts by inhibiting protein synthesis in bacteria. Oxytetracycline prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also po... | |||
T9033 | BTYNB | MDK6620,BTYNB IMP1 Inhibitor | Others , c-Myc , NF-κB |
BTYNB (MDK6620) is an inhibitor of the oncofetal mRNA-binding protein IMP1 (IC50 = 5 μM for IMP1 binding to c-Myc mRNA). MDK6620 downregulates β-TrCP1 mRNA and reduces activation of nuclear transcriptional factors-kappa ... | |||
T11836 | Lefamulin acetate | BC-3781 acetate | ribosome , Antibacterial , Antibiotic |
Lefamulin acetate (BC-3781 acetate) (formally BC-3781 acetate) is a novel pleuromutilin antibiotic and is the first to be used for the systemic treatment of bacterial infections in humans. Lefamulin acetate (BC-3781 acet... | |||
T15507 | Hycanthone | Etrenol(mesylate),Win 249-33 | DNA/RNA Synthesis , Topoisomerase , Parasite |
Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal. Hycanthone is a DNA intercalator that inhibits RNA synthesis and DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibit... | |||
T9120 | HBC | Benzeneacetonitrile, 4-cyano-α-[[4-[(2-hydroxyethyl)methylamino]phenyl]methylene]-,HBC 530 | Others |
HBC (HBC 530) 530 is a mimic of green fluorescent protein (GFP) fluorophore for imaging RNA in live cells. Fluoresces when bound to Pepper aptamer; displays high affinity binding (Kd = 3.5 nM). Suitable for confocal and ... | |||
T28762 | Setrobuvir | RO-5466731,ANA-598,RG7790,ANA598,RG-7790 | HCV Protease , SARS-CoV , DNA/RNA Synthesis |
Setrobuvir (ANA-598) is an orally active non-nucleoside HCV NS5B polymerase inhibitor with inhibitory effects on de novo RNA synthesis and primer extension with IC50s between 4 and 5 nM. setrobuvir shows good binding aff... |