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Search Results for " rna-binding "

20

Compounds

Cat No. Product Name Synonyms Targets
T81356 PTBP1-RNA-binding inhibitor P6 TFA PTBP1 α3-helix derived peptide P6 TFA
PTBP1-RNA-binding inhibitor P6 (PTBP1 α3-helix derived peptide P6) TFA is a stapled peptide that acts as an inhibitor for the splicing factor PTBP1, targeting the alternative splicing events this protein regulates. It op...
T16766 Ro 08-2750
Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor which binds to NGF, and with an IC50 of ~ 1 µM. Ro 08-2750 is a selective MSI RNA-binding activity inhibitor, with an IC50 of 2.7 μM. Ro 08-2...
T83729 Tat-CIRP TFA Tat-Cold-inducible RNA Binding Protein
Tat-CIRP, a peptide inhibitor, impedes the protein-protein interaction between myeloid differentiation 2 (MD-2), also known as lymphocyte antigen 96 (LY96), and cold-inducible RNA binding protein (CIRP) by binding to MD-...
T6823 E3330 HIF/HIF Prolyl-Hydroxylase , DNA/RNA Synthesis
E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.
T1822 Clemizole HCV Protease , Histamine Receptor
Clemizole is an H1 histamine receptor antagonist, can inhibit NS4B's RNA binding and hepatitis C virus (HCV) replication.
T1822L Clemizole hydrochloride HCV Protease , Histamine Receptor
Clemizole hydrochloride is an antagonist for H1 histamine receptor. According to the research, Clemizole hydrochloride can inhibit hepatitis C virus (HCV) replication and NS4B's RNA binding.
T27835 Lin281632 Lin-28 1632,Lin-281632,Lin 281632,Lin28 1632,Lin 28 163
Lin28 1632 is an inhibitor of RNA binding protein Lin28. It promotes mESC differentiation. Lin281632 is also bromodomain inhibitor.
T40122 L-Histidine benzyl ester bistosylate Others
L-Histidine benzyl ester bistosylate may serve as an activator for HutP, an RNA-binding protein.
T7330 Nucleozin Influenza Virus
Nucleozin targets influenza A nucleoprotein (NP), a multifunctional, RNA-binding protein necessary for virus replication.
T9879 Hydroxystilbamidine Oxistilbamidinum,(E)-hydroxystilbamidine,2-Hydroxy-4,4'-diguanylstilbene,Bis(8-hydroxyquinolinium) sulphate Others
Hydroxystilbamidine ((E)-hydroxystilbamidine), a dye capable of binding to both DNA and RNA, has been found to be a powerful inhibitor of cellular ribonucleases.
T1747 Tedizolid TR 700,DA-7157,Torezolid MAO , Antibacterial , Antibiotic
Tedizolid (DA-7157)is a novel oxazolidinone-class antibiotic that inhibits bacterial protein synthesis by binding to the 23S ribosomal RNA of the 50S subunit of the ribosome.
T73475 SMN-C2 DNA/RNA Synthesis
SMN-C2 is a selective regulator of SMN2 gene splicing, a risdiplam analogue, a selective RNA-binding ligand that regulates pre-mRNA splicing and acts by binding to SMN2 pre-mRNA.SMN-C2 has the potential to be used in the...
T2219 Puromycin dihydrochloride CL13900 dihydrochloride,Puromycin 2HCl ribosome , DNA/RNA Synthesis , Antibacterial , Antibiotic
Puromycin dihydrochloride (CL13900 dihydrochloride) is a cinnamamide adenosine antibiotic and an inhibitor of protein synthesis. Puromycin dihydrochloride inhibits protein synthesis by binding to RNA and has antitumor an...
TNU0091 3'-Deoxy-3'-fluoroguanosine Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
3'-Deoxy-3'-fluoroguanosine is a nucleoside phosphorylase inhibitor that inhibits RNA replication by binding replons. 3 '-Deoxy-3' -fluoroguanosine is used to treat viral hepatitis, cancer and other diseases.
T50026 Aquacycline HSV
Oxytetracycline (OTC) is a broad-spectrum antibiotic that acts by inhibiting protein synthesis in bacteria. Oxytetracycline prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also po...
T9033 BTYNB MDK6620,BTYNB IMP1 Inhibitor Others , c-Myc , NF-κB
BTYNB (MDK6620) is an inhibitor of the oncofetal mRNA-binding protein IMP1 (IC50 = 5 μM for IMP1 binding to c-Myc mRNA). MDK6620 downregulates β-TrCP1 mRNA and reduces activation of nuclear transcriptional factors-kappa ...
T11836 Lefamulin acetate BC-3781 acetate ribosome , Antibacterial , Antibiotic
Lefamulin acetate (BC-3781 acetate) (formally BC-3781 acetate) is a novel pleuromutilin antibiotic and is the first to be used for the systemic treatment of bacterial infections in humans. Lefamulin acetate (BC-3781 acet...
T15507 Hycanthone Etrenol(mesylate),Win 249-33 DNA/RNA Synthesis , Topoisomerase , Parasite
Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal. Hycanthone is a DNA intercalator that inhibits RNA synthesis and DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibit...
T9120 HBC Benzeneacetonitrile, 4-cyano-α-[[4-[(2-hydroxyethyl)methylamino]phenyl]methylene]-,HBC 530 Others
HBC (HBC 530) 530 is a mimic of green fluorescent protein (GFP) fluorophore for imaging RNA in live cells. Fluoresces when bound to Pepper aptamer; displays high affinity binding (Kd = 3.5 nM). Suitable for confocal and ...
T28762 Setrobuvir RO-5466731,ANA-598,RG7790,ANA598,RG-7790 HCV Protease , SARS-CoV , DNA/RNA Synthesis
Setrobuvir (ANA-598) is an orally active non-nucleoside HCV NS5B polymerase inhibitor with inhibitory effects on de novo RNA synthesis and primer extension with IC50s between 4 and 5 nM. setrobuvir shows good binding aff...

Compounds

PTBP1-RNA-binding inhibitor P6 TFA
T81356
Synonym: PTBP1 α3-helix derived peptide P6 TFA
Target:
Ro 08-2750
T16766
Synonym:
Target:
Tat-CIRP TFA
T83729
Synonym: Tat-Cold-inducible RNA Binding Protein
Target:
E3330
T6823
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase, DNA/RNA Synthesis
Clemizole
T1822
Synonym:
Target: HCV Protease, Histamine Receptor
Clemizole hydrochloride
T1822L
Synonym:
Target: HCV Protease, Histamine Receptor
Lin281632
T27835
Synonym: Lin-28 1632,Lin-281632,Lin 281632,Lin28 1632,Lin 28 163
Target:
L-Histidine benzyl ester bistosylate
T40122
Synonym:
Target: Others
Nucleozin
T7330
Synonym:
Target: Influenza Virus
Hydroxystilbamidine
T9879
Synonym: Oxistilbamidinum,(E)-hydroxystilbamidine,2-Hydroxy-4,4'-diguanylstilbene,Bis(8-hydroxyquinolinium) sulphate
Target: Others
Tedizolid
T1747
Synonym: TR 700,DA-7157,Torezolid
Target: MAO, Antibacterial, Antibiotic
SMN-C2
T73475
Synonym:
Target: DNA/RNA Synthesis
Puromycin dihydrochloride
T2219
Synonym: CL13900 dihydrochloride,Puromycin 2HCl
Target: ribosome, DNA/RNA Synthesis, Antibacterial, Antibiotic
3'-Deoxy-3'-fluoroguanosine
TNU0091
Synonym:
Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis
Aquacycline
T50026
Synonym:
Target: HSV
BTYNB
T9033
Synonym: MDK6620,BTYNB IMP1 Inhibitor
Target: Others, c-Myc, NF-κB
Lefamulin acetate
T11836
Synonym: BC-3781 acetate
Target: ribosome, Antibacterial, Antibiotic
Hycanthone
T15507
Synonym: Etrenol(mesylate),Win 249-33
Target: DNA/RNA Synthesis, Topoisomerase, Parasite
HBC
T9120
Synonym: Benzeneacetonitrile, 4-cyano-α-[[4-[(2-hydroxyethyl)methylamino]phenyl]methylene]-,HBC 530
Target: Others
Setrobuvir
T28762
Synonym: RO-5466731,ANA-598,RG7790,ANA598,RG-7790
Target: HCV Protease, SARS-CoV, DNA/RNA Synthesis
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TargetMol