Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Lefamulin acetate (BC-3781 acetate) (formally BC-3781 acetate) is a novel pleuromutilin antibiotic and is the first to be used for the systemic treatment of bacterial infections in humans. Lefamulin acetate (BC-3781 acetate) inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome, preventing the binding of transfer RNA for peptide transfer. Lefamulin acetate (BC-3781 acetate) is an orally active antibiotic for community-acquired bacterial pneumonia (CABP) treatment.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 98.00 | |
5 mg | In stock | $ 228.00 | |
10 mg | In stock | $ 347.00 | |
25 mg | In stock | $ 567.00 | |
50 mg | In stock | $ 767.00 | |
100 mg | In stock | $ 1,070.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 289.00 |
Description | Lefamulin acetate (BC-3781 acetate) (formally BC-3781 acetate) is a novel pleuromutilin antibiotic and is the first to be used for the systemic treatment of bacterial infections in humans. Lefamulin acetate (BC-3781 acetate) inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome, preventing the binding of transfer RNA for peptide transfer. Lefamulin acetate (BC-3781 acetate) is an orally active antibiotic for community-acquired bacterial pneumonia (CABP) treatment. |
In vitro | Lefamulin has activity against gram-negative organisms, including Haemophilus influenza (MIC50=1 μg/ml; MIC90=0.12 μg/ml) and Moraxella cotarrhali (MIC50=2 μg/ml; MIC90=0.25 μg/ml)[1].Lefamulin acetate (BC-3781 acetate) has activity against the resistant gram-postive organisms, including taphylococcus aureus (MRSA) (MIC50=0.12 μg/ml;?MIC90=0.25 μg/ml);?β-Hemolytic strepococcus (MIC50=0.03 μg/ml;?MIC90=0.03 μg/ml);?Viridans group Streptococcus (MIC50=0.12 μg/ml;?MIC90=0.5 μg/ml), Enterocossus faecium (MIC50=0.12 μg/ml;?MIC90=4 μg/ml), Streptococcus pneumonia (MIC50=0.12 μg/ml;?MIC90 =0.25 μg/ml)[1]. |
Synonyms | BC-3781 acetate |
Molecular Weight | 567.78 |
Formula | C30H49NO7S |
CAS No. | 1350636-82-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 99 mg/mL (174.36 mM)
You can also refer to dose conversion for different animals. More
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Lefamulin acetate 1350636-82-6 Microbiology/Virology Antibacterial Antibiotic ribosome Inhibitor Lefamulin BC-3781 acetate BC 3781 Acetate BC3781 Acetate BC 3781 BC3781 inhibit BC-3781 Bacterial Lefamulin Acetate BC-3781 Acetate inhibitor