pos — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6211	Posaconazole	SCH 56592,POS	Antifungal
	Posaconazole (POS) is a sterol C14ɑ demethylase inhibitor (IC50: 0.25 nM).		Antifungal
T81849	MAT-POS-e194df51-1		SARS-CoV
	MAT-POS-e194df51-1 is an orally active, non-covalent, non-peptide inhibitor of the SARS-CoV-2 main protease (M^pro) with an IC_50 of 37nM. It exhibits cytotoxicity, with EC_50 values of 64nM in A549-ACE2-TMPRSS2 cells an...		SARS-CoV
T9102	WM-3835		Apoptosis , Histone Methyltransferase , Histone Acetyltransferase
	WM-3835 is a novel and high-specific small molecule inhibitor of Lysine Acetyltransferase 7 (KAT7, MYST2, HBO1) , able to potently suppressed OS cell proliferation and migration, and leads to apoptosis activation.
T1523	Teniposide	NSC 122819,VM26	Topoisomerase
	Teniposide (VM26), a semisynthetic derivative of podophyllotoxin with antitumor activity, inhibits DNA synthesis by forming a complex with topoisomerase II and DNA.		Topoisomerase
T2136	Geniposidic Acid		Apoptosis , Others , Endogenous Metabolite
	Geniposidic acid, an iridoid glucoside, used in therapy of jaundice, inflammation and hepatic disorders.		Apoptosis , Others , Endogenous Metabolite
T0132	Etoposide	VP-16,VP-16-213	Apoptosis , Mitophagy , Topoisomerase , Antibacterial , Antibiotic , Autophagy
	Etoposide (VP-16-213) is a topoisomerase II inhibitor that inhibits DNA synthesis by forming a complex with topoisomerase II and DNA (IC50=60.3 μM). Etoposide has antitumor activity and induces apoptosis and autophagy.
TN3609	Catalposide	Hydroxybenzoyl catalpol	ERK , IL Receptor , TNF , NOS , NF-κB , NO Synthase , PPAR , Autophagy
	Catalposide is a potent inducer of (HO)-1 isolated from Catalpa ovate G. Don (Bignoniaceae). Catalposide possesses antioxidant, anti-apoptotic, anti-microbial, anti-tumoral, and anti-inflammatory properties.
T9079	Apostatin-1	Apt-1	Others
	Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 can bind to a pocket on the N-terminal TRAF2 binding domain of TRADD.		Others
T2212	Geniposide		Beta Amyloid , Influenza Virus
	Geniposide is an iridoid glycoside with a variety of biological activities including neuroprotective, anti-diabetic, antiproliferative, and antioxidative activity. Geniposide has been shown to regulate Nrf2 translocation...		Beta Amyloid , Influenza Virus
T34114	Posatirelin	BRN 6006446,Posatirelinum,BRN-6006446,RGH-2202,BRN6006446	AChR
	Posatirelin (BRN6006446) is a synthetic peptide with modulatory activity and neurotrophic effects on monoaminergic and cholinergic systems for the study of vascular dementia.		AChR
T68664	Epostane	Win-32729	Dehydrogenase
	Epostane (Win-32729) is a 3β-hydroxysteroid dehydrogenase inhibitor that acts by inhibiting the enzyme 3β-hydroxysteroid dehydrogenase, blocking progesterone production.		Dehydrogenase
T32378	Kenposide B
	Kenposide B is an aroma glycoside extracted from Hovenia dulsis.
T34495	Salireposide
	Salireposide is a salicinoid phenolic glycoside that is isolated from Symplocos racemosa.
T81929	Lipospondin
	Lipospondin, a bioactive peptide recognized for its anti-wrinkle properties, is utilized as a cosmetic ingredient [1].
T73997	Anti gram-positive/negative bacteria agent 1
	Anti gram-positive/negative bacteria agent 1 is an antibiotic linked with a synthetic MECAM-based siderophore, serving as a conjugate aimed at combating gram-positive and gram-negative bacteria.
T38607	Etoposide phosphate disodium	BMY-40481 disodium,Etoposide phosphate disodium
	Etoposide phosphate disodium (BMY-40481 disodium), a phosphate ester prodrug of etoposide, functions as a potent chemotherapeutic agent by selectively inhibiting topoisomerase II, hindering the re-ligation of DNA strands...
T81124	Sovipostobart
	Sovipostobart, an immunoglobulin G1-kappa monoclonal antibody targeting CTLA-4 in Homo sapiens, features a cleavable prodomain. This compound serves as both an immunostimulant and antineoplastic [1].
T34720	Stichoposide	Stichoposide A,Holotoxins
	Stichoposide is a triterpene glycoside.
T126527	Poststerone
	Poststerone is a useful organic compound for research related to life sciences and the catalog number is T126527.
TN3189	6'-O-p-Hydroxybenzoylcatalposide		Others
	6'-O-p-Hydroxybenzoylcatalposide is a natural product of Catalpa, Bignoniaceae. The catalog number is TN3189 and the CAS number is 355143-38-3. 6'-O-p-Hydroxybenzoylcatalposide can be used as a reference standard.		Others