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Search Results for " lap-1 "

Targets

2

Compounds

1

Natural Products

1751

Recombinant Proteins

Cat No. Product Name Synonyms Targets
TP2147 LSKL, Inhibitor of Thrombospondin (TSP-1) (TFA) Others
LSKL, Inhibitor of Thrombospondin (TSP-1) TFA, a latency-associated protein (LAP)-TGFβ derived tetrapeptide, is a competitive antagonist of TGF-β1.
T76498 H-Leu-Ser-Lys-Leu-OH
H-Leu-Ser-Lys-Leu-OH (LSYL), a latency-associated peptide located at the amino terminus of LAP, exhibits an inhibitory effect on TGF-β1 activation. By binding with KRFK, it obstructs TGF-β1 signal transduction, thereby i...
Cat No. Product Name Synonyms Targets
T6S1315 Oroxylin A 6-Methoxybaicalein,Baicalein 6-methyl ether Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
1. Oroxylin A (Baicalein 6-methyl ether) has various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion. 2. Oroxylin A possesses abilities of inhibiting the ATRA-induced IL-6 production v...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-00250 LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated Human Human Cells
Transforming growth factor beta (TGFβ) family members are secreted in inactive complexes with a latency-associated peptide (LAP), a protein derived from the N-terminal region of the TGFβ gene product. Extracellular activ...
TMPJ-00249 TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated Human Human Cells
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-...
TMPY-01133 Latent TGF beta 1 Protein, Human, Recombinant (His) Human HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-01478 HSP90 alpha Protein, Human, Recombinant Human E. coli
Heat shock protein 90 (90 kDa heat-shock protein, HSP90) is a molecular chaperone involved in the trafficking of proteins in the cell. It is a remarkably versatile protein involved in the stress response and normal homoe...
TMPY-00665 Aminopeptidase N/CD13 Protein, Human, Recombinant (I603M, His) Human HEK293
Aminopeptidase N (ANPEP or APN), also known as CD13, is a cell-surface metalloprotease located in the small-intestinal and renal microvillar membrane, as well as other plasma membranes. It belongs to the peptidase M1 fam...
TMPY-05521 Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated Human HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-06845 HSP90 alpha Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Heat shock protein 90 (90 kDa heat-shock protein, HSP90) is a molecular chaperone involved in the trafficking of proteins in the cell. It is a remarkably versatile protein involved in the stress response and normal homoe...
TMPY-02217 HSC70 Protein, Human, Recombinant (His) Human E. coli
HSPA8, also known as HSC70, is a member of the heat shock protein family due to homology with other heat shock proteins. The heat shock protein 70 family is comprised of both heat-inducible and constitutively expressed m...
TMPY-06553 CXCR4 Protein, Human, Recombinant Human HEK293
CXCR4 Protein, Human, Recombinant is expressed in HEK293. The predicted molecular weight is 39.75 kDa. Accession number: P61073-1
TMPJ-00966 GDF-5 Protein, Human, Recombinant Human E. coli
Growth Differentiation Factor 5(GDF-5, BMP-14) is a member of the BMP family of TGFβ superfamily proteins. Human GDF-5, -6, and -7 are a defined subgroup of the BMP family. GDF-5 is synthesized as a homodimeric precursor...
TMPY-03047 Stathmin 1 Protein, Human, Recombinant (His) Human E. coli
Stathmin1 (STMN1) is a cytosolic phosphoprotein that regulates cellular microtubule dynamics and is known to have oncogenic activity. STMN1 is a possible biomarker for paclitaxel sensitivity and poor prognosis in GC and ...
TMPJ-00254 TGF beta 3 Protein, Human/Mouse/Rat, Recombinant Human,Mouse,Rat Human Cells
Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes acti...
TMPH-00305 TGF-beta 1 Protein, Bovine, Recombinant (His) Bovine E. coli
Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1,...
TMPH-00382 TGF-beta 1 Protein, Chicken, Recombinant (His & SUMO) Chicken E. coli
Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1,...
TMPH-03206 ITGB8 Protein, Rabbit, Recombinant (His & Myc) Rabbit E. coli
Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor b...
TMPJ-00256 Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated Human Human Cells
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are...
TMPJ-00255 TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated Human Human Cells
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are...
TMPH-02231 NRROS Protein, Human, Recombinant (E. coli, His & Myc) Human E. coli
Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system. Required for activation of latent TGF-beta-1 in macrophages and microglia: associates specifi...
TMPH-02230 NRROS Protein, Human, Recombinant (His & Myc) Human Baculovirus
Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system. Required for activation of latent TGF-beta-1 in macrophages and microglia: associates specifi...
TMPH-02803 NRROS Protein, Mouse, Recombinant (His) Mouse E. coli
Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system. Required for activation of latent TGF-beta-1 in macrophages and microglia: associates specifi...
TMPJ-00802 THBS1 Protein, Human, Recombinant (His) Human Human Cells
Thrombospondin-1 (TSP-1) is a 150-180kDa calcium-sensitive protein that is secreted as a disulfide-linked homotrimer. TSP-1 regulates a wide range of cellular functions including their interactions with other cells and w...
TMPY-04451 AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus-Insect Cells
TMPY-03878 Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) Human HEK293
Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in th...
TMPY-02501 CD3D & CD3E Heterodimer Protein, Human, Recombinant Human HEK293
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 cells.
TMPY-03745 CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) Human HEK293
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 with Flag and His tag. The predicted molecular weight is 31.05 kDa. Accession number: P04234-1&P07766-1
TMPY-02794 TLR2 Protein, Human, Recombinant (aa 1-587, His) Human Baculovirus-Insect Cells
TLR2, also known as CD282, is a member of the Toll-like receptor (TLR) family. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They play a fundamental role in pathoge...
TMPY-03947 CD48 Protein, Human, Recombinant (hFc) Human HEK293
Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD4...
TMPY-03481 IL-1R2 Protein, Human, Recombinant Human HEK293
Interleukin 1 receptor, type II (IL1R2) also known as CD121b (Cluster of Differentiation 121b) is a cytokine receptor that belongs to the interleukin-1 receptor family. This protein binds interleukin alpha (IL1A), interl...
TMPK-00114 C-Reactive Protein /CRP Protein, Human, Recombinant (His) Human HEK293
C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate ...
TMPY-00740 SDF-1 Protein, Human, Recombinant (hFc) Human HEK293
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPY-04384 Src Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
Proto-oncogene tyrosine-protein kinase SRC is a hydrophobic protein belonging to the SRC family kinase including nine members that is a family of non-receptor tyrosine kinases. SRC protein may exist in different forms: C...
TMPK-01151 MXRA8 Protein, Human, Recombinant (His) Human HEK293
Mxra8 is a recently described receptor for multiple alphaviruses, including Chikungunya (CHIKV), Mayaro (MAYV), Ross River (RRV), and O'nyong nyong (ONNV) viruses.
TMPK-01074 CD163 Protein, Human, Recombinant (His & Avi) Human HEK293
The hemoglobin (Hb) scavenger receptor, CD163, is a macrophage-specific protein and the upregulated expression of this receptor is one of the major changes in the macrophage switch to alternative activated phenotypes in ...
TMPK-00383 ACE2/ACEH Protein, Human, Recombinant (His & Avi) Human HEK293
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angio...
TMPY-02525 RGMA Protein, Human, Recombinant (His) Human HEK293
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein th...
TMPY-04753 IRE1 Protein, Human, Recombinant (aa 465-977) Human Baculovirus-Insect Cells
Endoplasmic reticulum stress and hypoxia are necessary components of malignant tumors growth and suppression of ERN1 (from endoplasmic reticulum to nuclei-1) signalling pathway, which is linked to the apoptosis and cell ...
TMPY-04413 IRE1 Protein, Human, Recombinant (aa 465-977, His & GST) Human Baculovirus-Insect Cells
Endoplasmic reticulum stress and hypoxia are necessary components of malignant tumors growth and suppression of ERN1 (from endoplasmic reticulum to nuclei-1) signalling pathway, which is linked to the apoptosis and cell ...
TMPK-01393 Tenascin Protein, Mouse, Recombinant (His) Mouse HEK293
Tenascin-C (TNC) is a hexameric, multimodular extracellular matrix protein with several molecular forms that are created through alternative splicing and protein modifications. It is highly conserved amongst vertebrates,...
TMPK-00305 TGFBR1 Protein, Human, Recombinant (mFc & Avi) Human HEK293
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the sup...
TMPY-01460 ABHD4 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Abhydrolase domain containing 4 (ABHD4), also known as alpha/beta-hydrolase 4 (ABH4) , or lyso-N-acylphosphatidylethanolamine lipase, which belongs to the ABHD4/ABHD5 subfamily of peptidase S33 family. Abhydrolase domain...
TMPY-00978 Progranulin Protein, Human, Recombinant (His) Human HEK293
Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The precursor protein, progranulin, ...
TMPY-02227 IL-1 beta/IL-1F2 Protein, Rat, Recombinant (mature form) Rat E. coli
Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair ...
TMPY-05526 Siglec-15 Protein, Human, Recombinant (His) Human HEK293
Siglec-15 Protein, Human, Recombinant (His) is expressed in HEK293 cells.
TMPY-01963 IL-21 Protein, Human, Recombinant Human E. coli
IL21 belongs to the IL-15/IL-21 family. It is a cytokine with immunoregulatory activity. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellul...
TMPY-05781 LILRA6 Protein, Human, Recombinant (His) Human HEK293
LILRA6 Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 47.78 kDa. Accession number: Q6PI73-1
TMPY-06077 LILRA1/LIR-6/CD85i Protein, Human, Recombinant (hFc) Human HEK293
LILRA1/LIR-6/CD85i Protein, Human, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 75.3 kDa. Accession number: O75019-1
TMPY-05364 CD8 alpha Protein, Human, Recombinant (hFc) Human HEK293
T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been imp...
TMPY-04799 IFNAR2 Protein, Human, Recombinant (His), Biotinylated Human HEK293
Interferon-alpha/beta receptor beta chain (IFNAR2) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus protei...
TMPY-04970 TIGIT Protein, Human, Recombinant (hFc) Human HEK293
TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a tr...
TMPY-04826 LILRB5/CD85c Protein, Human, Recombinant (His) Human HEK293
A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) le...
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LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00250
Species: Human
Expression System: Human Cells
TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated
TMPJ-00249
Species: Human
Expression System: Human Cells
Latent TGF beta 1 Protein, Human, Recombinant (His)
TMPY-01133
Species: Human
Expression System: HEK293
HSP90 alpha Protein, Human, Recombinant
TMPY-01478
Species: Human
Expression System: E. coli
Aminopeptidase N/CD13 Protein, Human, Recombinant (I603M, His)
TMPY-00665
Species: Human
Expression System: HEK293
Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated
TMPY-05521
Species: Human
Expression System: HEK293
HSP90 alpha Protein, Human, Recombinant (His)
TMPY-06845
Species: Human
Expression System: Baculovirus-Insect Cells
HSC70 Protein, Human, Recombinant (His)
TMPY-02217
Species: Human
Expression System: E. coli
CXCR4 Protein, Human, Recombinant
TMPY-06553
Species: Human
Expression System: HEK293
GDF-5 Protein, Human, Recombinant
TMPJ-00966
Species: Human
Expression System: E. coli
Stathmin 1 Protein, Human, Recombinant (His)
TMPY-03047
Species: Human
Expression System: E. coli
TGF beta 3 Protein, Human/Mouse/Rat, Recombinant
TMPJ-00254
Species: Human,Mouse,Rat
Expression System: Human Cells
TGF-beta 1 Protein, Bovine, Recombinant (His)
TMPH-00305
Species: Bovine
Expression System: E. coli
TGF-beta 1 Protein, Chicken, Recombinant (His & SUMO)
TMPH-00382
Species: Chicken
Expression System: E. coli
ITGB8 Protein, Rabbit, Recombinant (His & Myc)
TMPH-03206
Species: Rabbit
Expression System: E. coli
Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00256
Species: Human
Expression System: Human Cells
TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated
TMPJ-00255
Species: Human
Expression System: Human Cells
NRROS Protein, Human, Recombinant (E. coli, His & Myc)
TMPH-02231
Species: Human
Expression System: E. coli
NRROS Protein, Human, Recombinant (His & Myc)
TMPH-02230
Species: Human
Expression System: Baculovirus
NRROS Protein, Mouse, Recombinant (His)
TMPH-02803
Species: Mouse
Expression System: E. coli
THBS1 Protein, Human, Recombinant (His)
TMPJ-00802
Species: Human
Expression System: Human Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
TMPY-04451
Species: Human
Expression System: Baculovirus-Insect Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
TMPY-03878
Species: Human
Expression System: HEK293
CD3D & CD3E Heterodimer Protein, Human, Recombinant
TMPY-02501
Species: Human
Expression System: HEK293
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)
TMPY-03745
Species: Human
Expression System: HEK293
TLR2 Protein, Human, Recombinant (aa 1-587, His)
TMPY-02794
Species: Human
Expression System: Baculovirus-Insect Cells
CD48 Protein, Human, Recombinant (hFc)
TMPY-03947
Species: Human
Expression System: HEK293
IL-1R2 Protein, Human, Recombinant
TMPY-03481
Species: Human
Expression System: HEK293
C-Reactive Protein /CRP Protein, Human, Recombinant (His)
TMPK-00114
Species: Human
Expression System: HEK293
SDF-1 Protein, Human, Recombinant (hFc)
TMPY-00740
Species: Human
Expression System: HEK293
Src Protein, Human, Recombinant (His & GST)
TMPY-04384
Species: Human
Expression System: Baculovirus-Insect Cells
MXRA8 Protein, Human, Recombinant (His)
TMPK-01151
Species: Human
Expression System: HEK293
CD163 Protein, Human, Recombinant (His & Avi)
TMPK-01074
Species: Human
Expression System: HEK293
ACE2/ACEH Protein, Human, Recombinant (His & Avi)
TMPK-00383
Species: Human
Expression System: HEK293
RGMA Protein, Human, Recombinant (His)
TMPY-02525
Species: Human
Expression System: HEK293
IRE1 Protein, Human, Recombinant (aa 465-977)
TMPY-04753
Species: Human
Expression System: Baculovirus-Insect Cells
IRE1 Protein, Human, Recombinant (aa 465-977, His & GST)
TMPY-04413
Species: Human
Expression System: Baculovirus-Insect Cells
Tenascin Protein, Mouse, Recombinant (His)
TMPK-01393
Species: Mouse
Expression System: HEK293
TGFBR1 Protein, Human, Recombinant (mFc & Avi)
TMPK-00305
Species: Human
Expression System: HEK293
ABHD4 Protein, Human, Recombinant (His)
TMPY-01460
Species: Human
Expression System: Baculovirus-Insect Cells
Progranulin Protein, Human, Recombinant (His)
TMPY-00978
Species: Human
Expression System: HEK293
IL-1 beta/IL-1F2 Protein, Rat, Recombinant (mature form)
TMPY-02227
Species: Rat
Expression System: E. coli
Siglec-15 Protein, Human, Recombinant (His)
TMPY-05526
Species: Human
Expression System: HEK293
IL-21 Protein, Human, Recombinant
TMPY-01963
Species: Human
Expression System: E. coli
LILRA6 Protein, Human, Recombinant (His)
TMPY-05781
Species: Human
Expression System: HEK293
LILRA1/LIR-6/CD85i Protein, Human, Recombinant (hFc)
TMPY-06077
Species: Human
Expression System: HEK293
CD8 alpha Protein, Human, Recombinant (hFc)
TMPY-05364
Species: Human
Expression System: HEK293
IFNAR2 Protein, Human, Recombinant (His), Biotinylated
TMPY-04799
Species: Human
Expression System: HEK293
TIGIT Protein, Human, Recombinant (hFc)
TMPY-04970
Species: Human
Expression System: HEK293
LILRB5/CD85c Protein, Human, Recombinant (His)
TMPY-04826
Species: Human
Expression System: HEK293
TargetMol