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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T13202 | Trilaciclib hydrochloride | G1T28 hydrochloride | CDK |
Trilaciclib hydrochloride (G1T28 hydrochloride) is an inhibitor of CDK4/6 (IC50s: 1 nM and 4 nM for CDK4 and CDK6). | |||
TQ0035 | Fulacimstat | BAY1142524 | Others |
Fulacimstat (BAY1142524) (BAY1142524) is a chymase inhibitor, with IC50s of 3, 4 nM for hamster and human chymase enzyme, respectively. | |||
T2012 | Oclacitinib | PF-03394197 | JAK |
Oclacitinib (PF-03394197)(PF03394197) is a potent and selective JAKs inhibitor with IC50 of 10-99 nM; not inhibit a panel of 38 non-JAK kinases (IC50 's > 1000 nM). | |||
T6914 | Oclacitinib maleate | PF-03394197 maleate,PF-03394197 | Tyrosine Kinases , JAK |
Oclacitinib maleate (PF-03394197 maleate) is a novel inhibitor of JAK family members with IC50 ranging from 10 to 99 nM and JAK1-dependent cytokines with IC50 ranging from 36 to 249 nM, which did not inhibit a panel of 3... | |||
T21113 | N2-Acetylaciclovir | Aciclovir EP Impurity F | Antibacterial |
N2-Acetylaciclovir (Aciclovir EP Impurity F) is a derivative of the antiviral compound Aciclovir, which has selective T-cell immunotoxicity. | |||
T27400L | Ganaplacide phosphate | Ganaplacide phosphate (1261113-96-5 Free base) | Others |
Ganaplacide phosphate exerts multi-stage antimalarial activity against Plasmodium symptomatic asexual blood-stage infections, and is able to prevent transmission and block infection in animal models. | |||
T1439 | Lacidipine | SN-305,GX-1048,GR-43659X | Apoptosis , Calcium Channel , Reactive Oxygen Species |
Lacidipine (SN-305) is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does not lead to reflex tachycardia. It displays specifi... | |||
T23617 | Aclacinomycin | Aclacinomycins,Siwenmycin | |
Aclacinomycin A is an anthracycline drug. It sensitizes K562 chronic myeloid leukemia cells to imatinib through p38MAPK-mediated erythroid differentiation. It is used in the treatment of cancer. | |||
T38608 | Brilacidin tetrahydrochloride | PMX 30063 tetrahydrochloride | |
Brilacidin tetrahydrochloride (PMX 30063 tetrahydrochloride) is a defensin mimetic antibiotic compound, exhibiting potent anti-infective antimicrobial activity against a range of bacteria. It demonstrates MIC90 values of... | |||
T39103 | Pafolacianine | OTL 38 | |
Pafolacianine (OTL 38) is a near-infrared dye-based fluorescent marker utilized for identifying ovarian cancer lesions during surgeries. | |||
T76894 | Abelacimab | ||
Abelacimab (MAA868), a fully human IgG1 monoclonal antibody, targets and binds with high affinity to FXI's catalytic structural domain. This interaction ensures FXI remains in its zymogen form, effectively inhibiting act... | |||
T71450 | Ilacirnon sodium | ||
Ilacirnon sodium is a potent CCR2 antagonist that may be useful in the treatment of renal diseases including Focal Segmental Glomerulosclerosis and Diabetic Nephropathy. | |||
T27400 | Ganaplacide | KAF 156,KAF-156,GNF-156,GNF 156,GNF156,KAF156 | |
Ganaplacide is an antimalarials with activity against asexual and sexual blood stages and the preerythrocytic liver stages of malarial parasites. KAF156 showed antimalarial activity without evident safety concerns in a s... | |||
T32524 | Laciniatin | ||
Laciniatin belongs to the class of organic compounds named flavonols. | |||
T25950 | Phosalacine | ||
Phosalacine, isolated from Kitasatosporia phosalacinea, is a new herbicidal antibiotic that contains phosphinothricin. | |||
T124640 | Fallacinol | ||
Fallacinol is a useful organic compound for research related to life sciences and the catalog number is T124640. | |||
T62677 | Ganaplacide hydrochloride | ||
Ganaplacide (KAF156) hydrochloride is a first-of-its-kind, orally active imidazolopiperazine antimalarial drug.Ganaplacide hydrochloride is active against a wide range of Plasmodium species, including drug-resistant para... | |||
T70002 | Salacinol | ||
Salacinol is a naturally occurring alpha-glucosidase inhibitor isolated from an Ayurvedic traditional medicine Salacia reticulata. | |||
T34815 | Tetcyclacis | Tetracyclacis,Ken BYO,Ken-BYO,KenBYO | |
Tetcyclacis is a plant growth retardant. | |||
T13202L | Trilaciclib | G1T28 | CDK |
Trilaciclib is an inhibitor of CDK4/6 (IC50s: 1 nM and 4 nM for CDK4 and CDK6, respectively). | |||
T14781 | Brilacidin | PMX 30063 | Others |
Brilacidin is a nonpeptidic anti-infective in a new class of defensin mimetics used for the research of eye infections. | |||
T75246 | Cyclacillin | ||
Cyclacillin (Wy-4508), an orally active aminopenicillin antibiotic, demonstrates broad-spectrum antibacterial efficacy against various gram-positive and gram-negative pathogens [1]. | |||
T78283 | Caplacizumab | ALX-0081,ALX-0681 | |
Caplacizumab (ALX-0681), a humanized anti-von Willebrand factor (vWF) nanobody, serves to impede vWF-mediated platelet adhesion, thereby averting additional microthrombi formation. This compound is utilized in the study ... | |||
T25674 | Leualacin | ||
Leualacin is a novel calcium blocker from Hapsidospora irregularis. | |||
T1087L | Valaciclovir | ||
Valacyclovir (Valaciclovir) is an orally active antiviral drug for herpes simplex, herpes zoster, and herpes B. Valacyclovir inhibits HSV-1 W with an IC50 of 2.9 μg/ml. Valacyclovir is a prodrug of Aciclovir [1] [2] [3] ... | |||
T125160 | Harmalacidine | ||
Harmalacidine is a useful organic compound for research related to life sciences and the catalog number is T125160. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN2091 | Polygalacin D | Apoptosis , IAP | |
Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-induced iNOS and COX-2 protein and mRNA without an appreciable cytotoxi... | |||
T3767 | Polygalacic acid | Virgaureagenin G | MMP , AChR , AChE |
Polygalacic acid (Virgaureagenin G)(PA) significantly improves cholinergic system reactivity, as indicated by decreased acetylcholinesterase (AChE) activity, increases choline acetyltransferase (ChAT) activity, and eleva... | |||
T21502 | Aclacinomycin A | ||
Aclacinomycin A has a wide range of applications in life science related research. | |||
T10238 | Aclacinomycin A hydrochloride | Aclarubicin hydrochloride | Proteasome |
Aclacinomycin A (Aclarubicin) hydrochloride is a fluorescent molecule and the first described non-peptidic inhibitor showing discrete specificity for the CTRL (chymotrypsin-like) activity of the 20S proteasome. Aclacinom... | |||
T40298 | Phallacidin | ||
Phallacidin, a phallotoxin family member, targets and binds to F-actin in mushroom toxins. | |||
T80953 | Tremulacin | ||
Tremulacin, a key glucoside found in the barks and leaves of various species of Populus, demonstrates significance [1]. | |||
T75529 | Malacidin B | ||
Malacidin B, a macrocyclic lipopeptide antibiotic, demonstrates calcium-dependent antibacterial activity [1] [2]. | |||
TN5330 | Lacinilene C | 3,10-Dihydroxy-1,3,5,7-cadinatetraen-9-one | |
Lacinilene C, lacinilene C 7-methyl ether, scopoletin, 2-hydroxy-7-methoxycadalene and 2,7-dihydroxycadalene are 5 induced phytoalexins in cotton leaves. Lacinilene C methyl ether elicits contraction of TSM by enhancing ... | |||
T75528 | Malacidin A | ||
Malacidin A is the calcium-dependent antibiotic (CDAs) . Malacidin A is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria [1] [2] . | |||
T78498 | Oxyphyllacinol | ||
Oxyphyllacinol, a naturally occurring compound, is derived from the fruit of Alpinia oxyphylla [1]. | |||
T32525 | Laciniatoside V | ||
Laciniatoside V is a metabolite. | |||
TN6437 | Polygalacin D2 | ||
Polygalacin D2 may have antimicrobial activity. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01030 | TFPI Protein, Human, Recombinant (His) | Human | HEK293 |
Tissue factor pathway inhibitor (TFPI) is the natural inhibitor of TF coagulant and signaling activities. It is a Kunitz-type serine proteinase inhibitor that down-regulates tissue factor-initiated blood coagulation. Wit... | |||
TMPK-00195 | TFPI Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and... | |||
TMPK-00194 | TFPI Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and... | |||
TMPY-00928 | TFPI Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Tissue factor pathway inhibitor (TFPI) is the natural inhibitor of TF coagulant and signaling activities. It is a Kunitz-type serine proteinase inhibitor that down-regulates tissue factor-initiated blood coagulation. Wit... | |||
TMPY-05179 | TFPI Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
Tissue factor pathway inhibitor (TFPI) is the natural inhibitor of TF coagulant and signaling activities. It is a Kunitz-type serine proteinase inhibitor that down-regulates tissue factor-initiated blood coagulation. Wit... | |||
TMPH-03210 | TFPI Protein, Rabbit, Recombinant (E. coli, His) | Rabbit | E. coli |
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability t... | |||
TMPH-03211 | TFPI Protein, Rabbit, Recombinant (His) | Rabbit | HEK293 |
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability t... |