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Search Results for " laci "

Targets

26

Compounds

12

Natural Products

7

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T13202 Trilaciclib hydrochloride G1T28 hydrochloride CDK
Trilaciclib hydrochloride (G1T28 hydrochloride) is an inhibitor of CDK4/6 (IC50s: 1 nM and 4 nM for CDK4 and CDK6).
TQ0035 Fulacimstat BAY1142524 Others
Fulacimstat (BAY1142524) (BAY1142524) is a chymase inhibitor, with IC50s of 3, 4 nM for hamster and human chymase enzyme, respectively.
T2012 Oclacitinib PF-03394197 JAK
Oclacitinib (PF-03394197)(PF03394197) is a potent and selective JAKs inhibitor with IC50 of 10-99 nM; not inhibit a panel of 38 non-JAK kinases (IC50 's > 1000 nM).
T6914 Oclacitinib maleate PF-03394197 maleate,PF-03394197 Tyrosine Kinases , JAK
Oclacitinib maleate (PF-03394197 maleate) is a novel inhibitor of JAK family members with IC50 ranging from 10 to 99 nM and JAK1-dependent cytokines with IC50 ranging from 36 to 249 nM, which did not inhibit a panel of 3...
T21113 N2-Acetylaciclovir Aciclovir EP Impurity F Antibacterial
N2-Acetylaciclovir (Aciclovir EP Impurity F) is a derivative of the antiviral compound Aciclovir, which has selective T-cell immunotoxicity.
T27400L Ganaplacide phosphate Ganaplacide phosphate (1261113-96-5 Free base) Others
Ganaplacide phosphate exerts multi-stage antimalarial activity against Plasmodium symptomatic asexual blood-stage infections, and is able to prevent transmission and block infection in animal models.
T1439 Lacidipine SN-305,GX-1048,GR-43659X Apoptosis , Calcium Channel , Reactive Oxygen Species
Lacidipine (SN-305) is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does not lead to reflex tachycardia. It displays specifi...
T23617 Aclacinomycin Aclacinomycins,Siwenmycin
Aclacinomycin A is an anthracycline drug. It sensitizes K562 chronic myeloid leukemia cells to imatinib through p38MAPK-mediated erythroid differentiation. It is used in the treatment of cancer.
T38608 Brilacidin tetrahydrochloride PMX 30063 tetrahydrochloride
Brilacidin tetrahydrochloride (PMX 30063 tetrahydrochloride) is a defensin mimetic antibiotic compound, exhibiting potent anti-infective antimicrobial activity against a range of bacteria. It demonstrates MIC90 values of...
T39103 Pafolacianine OTL 38
Pafolacianine (OTL 38) is a near-infrared dye-based fluorescent marker utilized for identifying ovarian cancer lesions during surgeries.
T76894 Abelacimab
Abelacimab (MAA868), a fully human IgG1 monoclonal antibody, targets and binds with high affinity to FXI's catalytic structural domain. This interaction ensures FXI remains in its zymogen form, effectively inhibiting act...
T71450 Ilacirnon sodium
Ilacirnon sodium is a potent CCR2 antagonist that may be useful in the treatment of renal diseases including Focal Segmental Glomerulosclerosis and Diabetic Nephropathy.
T27400 Ganaplacide KAF 156,KAF-156,GNF-156,GNF 156,GNF156,KAF156
Ganaplacide is an antimalarials with activity against asexual and sexual blood stages and the preerythrocytic liver stages of malarial parasites. KAF156 showed antimalarial activity without evident safety concerns in a s...
T32524 Laciniatin
Laciniatin belongs to the class of organic compounds named flavonols.
T25950 Phosalacine
Phosalacine, isolated from Kitasatosporia phosalacinea, is a new herbicidal antibiotic that contains phosphinothricin.
T124640 Fallacinol
Fallacinol is a useful organic compound for research related to life sciences and the catalog number is T124640.
T62677 Ganaplacide hydrochloride
Ganaplacide (KAF156) hydrochloride is a first-of-its-kind, orally active imidazolopiperazine antimalarial drug.Ganaplacide hydrochloride is active against a wide range of Plasmodium species, including drug-resistant para...
T70002 Salacinol
Salacinol is a naturally occurring alpha-glucosidase inhibitor isolated from an Ayurvedic traditional medicine Salacia reticulata.
T34815 Tetcyclacis Tetracyclacis,Ken BYO,Ken-BYO,KenBYO
Tetcyclacis is a plant growth retardant.
T13202L Trilaciclib G1T28 CDK
Trilaciclib is an inhibitor of CDK4/6 (IC50s: 1 nM and 4 nM for CDK4 and CDK6, respectively).
T14781 Brilacidin PMX 30063 Others
Brilacidin is a nonpeptidic anti-infective in a new class of defensin mimetics used for the research of eye infections.
T75246 Cyclacillin
Cyclacillin (Wy-4508), an orally active aminopenicillin antibiotic, demonstrates broad-spectrum antibacterial efficacy against various gram-positive and gram-negative pathogens [1].
T78283 Caplacizumab ALX-0081,ALX-0681
Caplacizumab (ALX-0681), a humanized anti-von Willebrand factor (vWF) nanobody, serves to impede vWF-mediated platelet adhesion, thereby averting additional microthrombi formation. This compound is utilized in the study ...
T25674 Leualacin
Leualacin is a novel calcium blocker from Hapsidospora irregularis.
T1087L Valaciclovir
Valacyclovir (Valaciclovir) is an orally active antiviral drug for herpes simplex, herpes zoster, and herpes B. Valacyclovir inhibits HSV-1 W with an IC50 of 2.9 μg/ml. Valacyclovir is a prodrug of Aciclovir [1] [2] [3] ...
T125160 Harmalacidine
Harmalacidine is a useful organic compound for research related to life sciences and the catalog number is T125160.
Cat No. Product Name Synonyms Targets
TN2091 Polygalacin D Apoptosis , IAP
Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-induced iNOS and COX-2 protein and mRNA without an appreciable cytotoxi...
T3767 Polygalacic acid Virgaureagenin G MMP , AChR , AChE
Polygalacic acid (Virgaureagenin G)(PA) significantly improves cholinergic system reactivity, as indicated by decreased acetylcholinesterase (AChE) activity, increases choline acetyltransferase (ChAT) activity, and eleva...
T21502 Aclacinomycin A
Aclacinomycin A has a wide range of applications in life science related research.
T10238 Aclacinomycin A hydrochloride Aclarubicin hydrochloride Proteasome
Aclacinomycin A (Aclarubicin) hydrochloride is a fluorescent molecule and the first described non-peptidic inhibitor showing discrete specificity for the CTRL (chymotrypsin-like) activity of the 20S proteasome. Aclacinom...
T40298 Phallacidin
Phallacidin, a phallotoxin family member, targets and binds to F-actin in mushroom toxins.
T80953 Tremulacin
Tremulacin, a key glucoside found in the barks and leaves of various species of Populus, demonstrates significance [1].
T75529 Malacidin B
Malacidin B, a macrocyclic lipopeptide antibiotic, demonstrates calcium-dependent antibacterial activity [1] [2].
TN5330 Lacinilene C 3,10-Dihydroxy-1,3,5,7-cadinatetraen-9-one
Lacinilene C, lacinilene C 7-methyl ether, scopoletin, 2-hydroxy-7-methoxycadalene and 2,7-dihydroxycadalene are 5 induced phytoalexins in cotton leaves. Lacinilene C methyl ether elicits contraction of TSM by enhancing ...
T75528 Malacidin A
Malacidin A is the calcium-dependent antibiotic (CDAs) . Malacidin A is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria [1] [2] .
T78498 Oxyphyllacinol
Oxyphyllacinol, a naturally occurring compound, is derived from the fruit of Alpinia oxyphylla [1].
T32525 Laciniatoside V
Laciniatoside V is a metabolite.
TN6437 Polygalacin D2
Polygalacin D2 may have antimicrobial activity.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01030 TFPI Protein, Human, Recombinant (His) Human HEK293
Tissue factor pathway inhibitor (TFPI) is the natural inhibitor of TF coagulant and signaling activities. It is a Kunitz-type serine proteinase inhibitor that down-regulates tissue factor-initiated blood coagulation. Wit...
TMPK-00195 TFPI Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and...
TMPK-00194 TFPI Protein, Human, Recombinant (His & Avi) Human HEK293
Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and...
TMPY-00928 TFPI Protein, Mouse, Recombinant (His) Mouse HEK293
Tissue factor pathway inhibitor (TFPI) is the natural inhibitor of TF coagulant and signaling activities. It is a Kunitz-type serine proteinase inhibitor that down-regulates tissue factor-initiated blood coagulation. Wit...
TMPY-05179 TFPI Protein, Human, Recombinant (His), Biotinylated Human HEK293
Tissue factor pathway inhibitor (TFPI) is the natural inhibitor of TF coagulant and signaling activities. It is a Kunitz-type serine proteinase inhibitor that down-regulates tissue factor-initiated blood coagulation. Wit...
TMPH-03210 TFPI Protein, Rabbit, Recombinant (E. coli, His) Rabbit E. coli
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability t...
TMPH-03211 TFPI Protein, Rabbit, Recombinant (His) Rabbit HEK293
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability t...
TargetMol