Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Polygalacin D2 may have antimicrobial activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | $ 390.00 | |
1 mL * 10 mM (in DMSO) | Inquiry | $ 890.00 |
Description | Polygalacin D2 may have antimicrobial activity. |
In vitro | METHODS AND RESULTS: A novel triterpenoid saponin, deapioplatycoside E (1) was isolated from the root extract of Platycodon grandiflorum, together with the seven known saponins 2 - 8, i. e., platycoside E (2), deapioplatycodin D3 (3), platycodin D3 (4), Polygalacin D2 (5), platycodin D2 (6), deapioplatycodin D (7) and platycodin D (8). The structure of the new saponin 1 was determined on the basis of spectral analysis and chemical evidence. CONCLUSIONS: The crude saponin fraction (ED50: ca. 10 - 15 microg/mL) and compounds 6 - 8 (ED50: ca. 4 - 18 microg/mL) exhibited significant inhibition on the proliferation of five kinds of cultured human tumor cell lines, i. e., A549 (non-small cell lung), SK-OV-3 (ovary), SK-MEL-2 (melanoma), XF498 (central nerve system) and HCT-15 (colon), in vitro. |
Source |
Molecular Weight | 1371.477 |
Formula | C63H102O32 |
CAS No. | 66663-92-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Polygalacin D2 66663-92-1 Polygalacin D-2 inhibitor inhibit