24
5
43
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11762L | Kira8 | AMG-18 | IRE1 |
Kira8 (AMG-18) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity (IC50: 5.9 nM). | |||
TQ0076 | KIRA6 | IRE1 | |
KIRA6 is an effective inhibitor of IRE1α RNase kinase (IC50: 0.6 μM). It can trigger an apoptotic response. | |||
T28950 | Terlakiren | CP 80794,CP-80,794 | RAAS |
Terlakiren (CP-80,794) is an orally active and potent renin inhibitor that inhibits the potency of human renin for the study of neurological disorders of the hypertension class. | |||
T1520 | Aliskiren hemifumarate | CGP 60536,SPP 100,CGP60536B | RAAS , Autophagy |
Aliskiren hemifumarate (CGP60536B) is an orally active nonpeptide renin inhibitor with antihypertensive activity. | |||
T70654 | Ciprokiren | ||
Ciprokiren is a renin inhibitor discovered by Roche. Ciprokinen inhibited human renin in a buffer and human plasma with an IC50 of 0.07 and 0.65 nmol/L, respectively. In animal models, acute and chronic administration of... | |||
T64163 | Aliskiren hydrochloride | ||
Aliskiren (CGP 60536; CGP60536B; SPP 100) hydrochloride is a selective, orally active, renin inhibitor (IC50: 1.5 nM). Cachexia. | |||
T15664 | KIRA-7 | Others | |
KIRA-7 is an imidazopyrazine compound. KIRA-7 has an anti-fibrotic effect. KIRA-7 binds the IRE1α kinase (IC50: 110 nM) to allosterically inhibit its RNase activity. | |||
T64049 | KIRA9 | ||
KIRA9 is a potent inhibitor of IRE1 with an IC50 value of 4.8 μM for INS-1 cells. KIRA9 completely binds the ATP binding site of IRE1 and blocks endoplasmic reticulum (ER) localised mRNA decay and apoptosis. | |||
T124633 | Neosenkirkine | ||
Neosenkirkine is a useful organic compound for research related to life sciences. The catalog number is T124633 and the CAS number is 57194-70-4. | |||
T22233 | Aliskiren | ||
Aliskiren(CGP 60536) is an orally effective renin inhibitor with IC50 of 1.5 nM. IC50 value: 1.5 nM [1] Target: renin in vitro: Aliskiren hemifumarate appears to bind to both the hydrophobic S1/S3-binding pocket and to a... | |||
T10282 | Aliskiren D6 Hydrochloride | SPP 100 D6 Hydrochloride,CGP60536B D6 Hydrochloride,CGP 60536 D6 Hydrochloride | Others |
Aliskiren (CGP 60536) D6 Hydrochloride is a deuterium-labeled Aliskiren. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: 1.5 nM). | |||
T29204 | Zankiren | A72517,A-72517,A 72617 | |
Zankiren is a renin inhibitor. Zankiren can reduce blood pressure, plasma renin activity, and angiotension II. | |||
T34285 | Remikiren | D09038,C07465,126222-34-2,AC1O44IV,CHEMBL31601 | |
Remikiren is a highly specific renin inhibitor with oral activity for the treatment of hypertensio. | |||
T72526 | Aliskiren fumarate | CGP 60536 fumarate,SPP 100 fumarate,CGP 60536 fumarate ; CGP60536B fumarate ; SPP 100 fumarate,CGP60536B fumarate | |
Aliskiren fumarate, an orally active, highly potent, and selective renin inhibitor with an IC50 of 1.5 nM, is utilized in the research of hypertension, cardiovascular diseases, and cancer cachexia. | |||
T27261 | Enalkiren | A-64662,A64662,A 64662 | |
Enalkiren is a dipeptide renin inhibitor used in treating cogenstive heart failure. Enalkiren causes a prolonged reduction in blood pressure. | |||
T19187 | Aliskiren D6 hemifumarate | CGP 60536 D6 hemifumarate,SPP 100 D6 hemifumarate,CGP60536B D6 hemifumarate | RAAS |
Aliskiren (CGP 60536) D6 hemifumarate is a deuterium-labeled Aliskiren hemifumarate. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: 1.5 nM). | |||
T11762 | Kira8 Hydrochloride | AMG-18 Hydrochloride | Adenosine Receptor |
Kira8 Hydrochloride is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM. | |||
T25345 | Ditekiren | U 71038,U71038,U-71038,Ditekirenum | |
Ditekiren is a renin inhibitor with orally active. | |||
T27595 | Imarikiren HCl | TAK-272 hydrochloride,TAK-272 HCl. Imarikiren HCl |,TAK272,TAK 272,TAK-272 | |
Imarikiren is a potent, selective and orally active direct renin inhibitor. TAK-272 shows potent inhibitory activity against human renin (IC50 = 2.1 nM) in hPRA assay and excellent selectivity against other aspartic prot... | |||
T16110 | ML418 | Potassium Channel | |
ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1. | |||
T27709 | K67 | K 67,K-67 | |
K67 is a specific inhibitor against the interaction between KEAP1 DC domain and S349-phosphorylated KIR of p62/SQSTM1. | |||
T83749 | Tertiapin LQ TFA | TPNLQ | |
Tertiapin LQ, a peptide derivative of honeybee venom peptide tertiapin, acts as an inhibitor of inwardly rectifying potassium (Kir) channels. Specifically, it targets and inhibits heteromultimeric potassium channels, inc... | |||
T71284 | Glimepiride urethane | ||
Glimepiride urethane is a third generation sulfonylurea compound, which increases the release of insulin from pancreatic beta cells. In addition, glimepiride increases the activity of intracellular insulin receptors. Gli... | |||
T37199 | Bilaid C | ||
Bilaid C is a tetrapeptide μ-opioid receptor agonist (Ki= 210 nM in HEK293 cell membranes expressing the human receptor) that has been found inPenicillium.1It inhibits forskolin-induced cAMP accumulation by 77% in HEK293... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4S1943 | Kirenol | Kirel | Wnt/beta-catenin |
1. Kirenol (Kirel) has anti-oxidant, anti-inflammatory, anti-allergic, and anti-arthritic activities. 2. Kirenol is effective against gram-positive bacteria. 3. Kirenol possesses antitumor action on human chronic myeloid... | |||
T20635 | Senkirkin | Renardin | |
Senkirkin is a pyrrolizidine alkaloid with hepatotoxicity. | |||
T38275 | Kirromycin | ||
Kirromycin is an antibiotic originally isolated from Streptomyces and an inhibitor of protein biosynthesis. It inhibits isoleucine incorporation, polyphenylalanine synthesis, and growth of B. brevis. Kirromycin inhibits ... | |||
TN5164 | Trans-Hinokiresinol | IL Receptor , TNF , NOS , LTR | |
Hinokiresinol is a novel inhibitor of LTB4 binding to the human neutrophils, it has antiallergic effect, it inhibits IgE-induced mouse passive cutaneous anaphylaxis reaction. Hinokiresinol (trans-hinokiresinol) and nyaso... | |||
TN3632 | (-)-Chelidonine | Others | |
(-)-Chelidonine is a natural product from Glaucium squamigerum KAR. et KIR. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02237 | KIR2DL3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
KIR2DL3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.9 kDa and the accession number is Q32WE4. | |||
TMPY-05442 | KIR2DL3 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
KIR2DL3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.6 kDa and the accession number is Q32WE4. | |||
TMPY-02629 | KIR2DL1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
KIR2DL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26 kDa and the accession number is Q6H2H3. | |||
TMPY-03651 | KIR2DL4 Protein, Human, Recombinant (hFc) | Human | CHO Cells |
KIR2DL4 Protein, Human, Recombinant (hFc) is expressed in CHO mammalian cells with hFc tag. The predicted molecular weight is 54.4 kDa and the accession number is ADY38409.1. | |||
TMPY-03652 | KIR2DL4 Protein, Human, Recombinant | Human | CHO Cells |
KIR2DL4 Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 50.3 kDa and the accession number is ADY38409.1. | |||
TMPK-00886 | KIR2DL3 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
KIR2DL3 (2DL3, formerly NKAT2, designated CD158b2) is a 341 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig‑like receptor (KIR) family of molecules. KIRs are expressed on human ... | |||
TMPK-00885 | KIR2DL3 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
KIR2DL3 (2DL3, formerly NKAT2, designated CD158b2) is a 341 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig‑like receptor (KIR) family of molecules. KIRs are expressed on human ... | |||
TMPK-00461 | KIR2DL1 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
KIR2DL1 (2DL1, formerly NKAT1, designated CD158a) is a 348 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig-like receptor (KIR) family.KIR2DL1 is a receptor on natural killer (NK... | |||
TMPK-00462 | KIR2DL1 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
KIR2DL1 (2DL1, formerly NKAT1, designated CD158a) is a 348 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig-like receptor (KIR) family.KIR2DL1 is a receptor on natural killer (NK... | |||
TMPY-00217 | KIR3DL3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
KIR3DL3 (Killer Cell Immunoglobulin Like Receptor, Three Ig Domains And Long Cytoplasmic Tail 3) is a Protein Coding gene. KIR3DL3 is a framework gene of the Leukocyte Receptor Complex, present in all individuals and hap... | |||
TMPY-02517 | KIR2DL1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
KIR2DL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.7 kDa and the accession number is Q6H2H3. | |||
TMPJ-00604 | KIR2DL4 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Killer cell immunoglobulin-like receptor 2DL4(KIR2DL4) is a Single-pass type I membrane protein and contains 2 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily. KIR2DL4 is expres... | |||
TMPK-00256 | KIR3DL3 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Killer-cell immunoglobulin-like receptor (KIR) 3DL3 is a framework gene present in all human KIR haplotypes.KIR3DL3 has been shown to be constitutively expressed at a low RNA level in peripheral blood mononuclear cell (P... | |||
TMPK-00257 | KIR3DL3 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Killer-cell immunoglobulin-like receptor (KIR) 3DL3 is a framework gene present in all human KIR haplotypes.KIR3DL3 has been shown to be constitutively expressed at a low RNA level in peripheral blood mononuclear cell (P... | |||
TMPK-00700 | KIR2DL5 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
A recently developed anti-KIR2DL5 (CD158f) antibody has demonstrated KIR2DL5 expression on the surface of NK and T lymphocytes, making it the last functional KIR identified in the human genome. KIR2DL5 belongs to an ance... | |||
TMPK-00701 | KIR2DL5 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
A recently developed anti-KIR2DL5 (CD158f) antibody has demonstrated KIR2DL5 expression on the surface of NK and T lymphocytes, making it the last functional KIR identified in the human genome. KIR2DL5 belongs to an ance... | |||
TMPK-00647 | KIR3DL2 Protein, Rhesus macaque, Recombinant (His) | Rhesus | HEK293 Cells |
KIR3DL2 is a member of the killer cell immunoglobulin-like receptor (KIR) family that was initially identified at the surface of natural killer (NK) cells. KIR3DL2, also known as CD158k, is expressed as a disulfide-linke... | |||
TMPK-00887 | KIR3DL2 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
KIR3DL2 is a member of the killer cell immunoglobulin-like receptor (KIR) family that was initially identified at the surface of natural killer (NK) cells. KIR3DL2, also known as CD158k, is expressed as a disulfide-linke... | |||
TMPK-00883 | KIR2DL2 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
KIR2DL2 (2DL2, formerly NKAT6, designated CD158b) is a 348 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig‑like receptor (KIR) family. KIRs are expressed on human CD56dim NK cel... | |||
TMPK-00884 | KIR2DL2 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
KIR2DL2 (2DL2, formerly NKAT6, designated CD158b) is a 348 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig‑like receptor (KIR) family. KIRs are expressed on human CD56dim NK cel... | |||
TMPY-05086 | KIR2DL5 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
KIR2DL5A (Killer Cell Immunoglobulin Like Receptor, Two Ig Domains And Long Cytoplasmic Tail 5A) is a Protein Coding gene. The encoded protein belongs to the immunoglobulin superfamily. The most recently described member... | |||
TMPH-01588 | KIR2DS1 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Receptor on natural killer (NK) cells for some HLA-C alleles such as w6. Does not inhibit the activity of NK cells. | |||
TMPH-03645 | Alpha-TCS Protein, Trichosanthes kirilowii, Recombinant (His) | Trichosanthes kirilowii | E. coli |
Inactivates eukaryotic 60S ribosomal subunits. Alpha-TCS Protein, Trichosanthes kirilowii, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 30.8 kDa and the... | |||
TMPH-01590 | KIR2DS3 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells. KIR2DS3 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. T... | |||
TMPH-01589 | KIR2DS3 Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells. | |||
TMPH-01586 | KIR2DL5B Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Receptor on natural killer (NK) cells for HLA-C alleles. Inhibits the activity of NK cells thus preventing cell lysis. KIR2DL5B Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10x... | |||
TMPY-04131 | KIRREL Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
KIRREL Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 78.8 kDa and the accession number is Q96J84-1. | |||
TMPY-04238 | KIRREL2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
KIRREL2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.3 kDa and the accession number is Q6UWL6-2. | |||
TMPY-01015 | KIRREL Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
KIRREL Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 53.8 kDa and the accession number is Q80W68-1. | |||
TMPH-01587 | KIR2DS1 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Receptor on natural killer (NK) cells for some HLA-C alleles such as w6. Does not inhibit the activity of NK cells. KIR2DS1 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHi... | |||
TMPY-03241 | KIRREL3 Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
KIRREL3 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.4 kDa and the accession number is Q09GS6. | |||
TMPY-00003 | KIRREL2 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
KIRREL2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 77.6 kDa and the accession number is Q6UWL6-1. | |||
TMPY-02089 | KIRREL3 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
KIRREL3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.5 kDa and the accession number is Q8BR86-1. | |||
TMPK-01100 | LILRB2/CD85d/ILT4 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as... | |||
TMPK-01102 | LILRB2/CD85d/ILT4 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as... | |||
TMPK-01314 | LILRB2/CD85d/ILT4 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as... | |||
TMPK-01099 | LILRB2/CD85d/ILT4 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as... | |||
TMPK-01313 | LILRB2/CD85d/ILT4 Protein, Cynomolgus, Recombinant (hFc) | Cynomolgus | HEK293 Cells |
The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as... | |||
TMPK-01101 | LILRB2/CD85d/ILT4 Domain1 & 2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as... | |||
TMPK-01098 | LILRB2/CD85d/ILT4 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as... | |||
TMPY-02805 | GNGT1 Protein, Human, Recombinant (His) | Human | E. coli |
GNGT1 is a subunit of transducin. Heterotrimeric G proteins consist of alpha, beta, and gamma subunits. They are membrane-bound GTPases that are linked to 7-TM receptors. They function as signal transducers for the 7-tra... | |||
TMPJ-00552 | LILRB2/CD85d/ILT4 Protein, Human, Recombinant (Avi & His), Biotinylated | Human | HEK293 Cells |
Members of the immunoglobulin-like transcript (ILT) family are activating and inhibitory immunoreceptors whose genes are located same locus that encodes killer cell Ig-like receptors (KIR). Leukocyte Immunoglobulin-Like ... | |||
TMPY-02802 | GNG13 Protein, Human, Recombinant (His) | Human | E. coli |
GNG13 is a subunit of heterotrimeric G proteins which consist of alpha, beta, and gamma subunits. Heterotrimeric G proteins are membrane-bound GTPases that are linked to 7-TM receptors. They function as signal transducer... |