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trans-Hinokiresinol

Catalog No. TN5164   CAS 17676-24-3

Hinokiresinol is a novel inhibitor of LTB4 binding to the human neutrophils, it has antiallergic effect, it inhibits IgE-induced mouse passive cutaneous anaphylaxis reaction. Hinokiresinol (trans-hinokiresinol) and nyasol (cis-hinokiresinol) are estrogen agonists, they possess appreciable estrogen receptor binding activity, they can stimulate the proliferation of estrogen- dependent T47D breast cancer cells, and their stimulatory effects could be blocked by an estrogen antagonist. They have similar free radical scavenging and anti-inflammatory activities, they also have anti-ischemic effects, only trans-hinokiresinol can significantly decrease neuronal injury in cultured cortical neurons exposed to oxygen-glucose deprivation followed by re-oxygenation.

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trans-Hinokiresinol Chemical Structure
trans-Hinokiresinol, CAS 17676-24-3
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Hinokiresinol is a novel inhibitor of LTB4 binding to the human neutrophils, it has antiallergic effect, it inhibits IgE-induced mouse passive cutaneous anaphylaxis reaction. Hinokiresinol (trans-hinokiresinol) and nyasol (cis-hinokiresinol) are estrogen agonists, they possess appreciable estrogen receptor binding activity, they can stimulate the proliferation of estrogen- dependent T47D breast cancer cells, and their stimulatory effects could be blocked by an estrogen antagonist. They have similar free radical scavenging and anti-inflammatory activities, they also have anti-ischemic effects, only trans-hinokiresinol can significantly decrease neuronal injury in cultured cortical neurons exposed to oxygen-glucose deprivation followed by re-oxygenation.
Source
Molecular Weight 252.313
Formula C17H16O2
CAS No. 17676-24-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

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Keywords

trans-Hinokiresinol 17676-24-3 Apoptosis Immunology/Inflammation LTR TNF NOS IL Receptor transHinokiresinol trans Hinokiresinol inhibitor inhibit

 

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