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Search Results for " ischemia "

20

Compounds

Cat No. Product Name Synonyms Targets
TN1895 Luteolinidin chloride CD38
Luteolinidin chloride is a natural product. It is a potent CD38 inhibitor which can protect the heart against I/R injury with preservation of eNOS function and prevention of endothelial dysfunction in vivo.
T3672 Nomilin MAPK
Nomilin is naturally occurring triterpenoids, have immunomodulatory activity.
T10979 DCPIB Potassium Channel , Chloride channel
DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μM, demonstrating at least 100-fold higher affinity over TREK1...
T3102 NS-1619 Apoptosis , Potassium Channel
NS1619 have cardio-protective effects after ischemia-reperfusion injury.
T10696 CB2 modulator 1 Cannabinoid Receptor
CB2 modulator 1 is a potent CB2 modulator. It can be used for the research for immune disorders, osteoporosis, inflammation, renal ischemia.
T2058 Palosuran ACT-058362 GPR
Palosuran (ACT-058362) (ACT-058362) is a new potent and specific antagonist of the human UT receptor.
T9765 TJ-M2010-5 MyD88
TJ-M2010-5 is a MyD88 inhibitor that binds to the TIR domain to interfere with its homodimerization and suppress MyD88 signaling. TJ-M2010-5 can be used in myocardial ischemia/reperfusion injury studies.
T2919 Sesamin Fagarol,Fsesamin Others
Sesamin (Fsesamin) is a lignan extracted from Sesamum indicum L.
T9073 SRS16-86 Ferroptosis
SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.
T5654 Musk ketone Others
Musk ketone can induce the growth repression and the apoptosis of cancer cells. Musk ketone increases activity of glutathione S-transferase and thus may prove to be useful cancer chemoprotectant.
T9714 Atpenin A5 Potassium Channel
Atpenin A5 is a potent and highly specific complex II inhibitor (IC50 ~10 nM). Atpenin A5 is also an effective mKATP channel agonist and cardioprotective agent[1].
T22537 9-Phenanthrol TRP/TRPV Channel
9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated non-selective cation channel.
T24109 GSK329 GSK 329,GSK-329 Others
GSK329 is an effective and selective inhibitor of TNNI3 Interacting Kinase (TNNI3K). GSK329 exhibits positive cardioprotective outcomes in the model of ischemia/reperfusion cardiac injury.
TN6490 Regaloside C Others
Regaloside C is a glycerol glucoside isolated from Lilium genus with anti-inflammatory properties.
T9232 Mitochondrial fusion promoter M1 Mitochondrial Metabolism
Mitochondrial fusion promoter M1, a modulator of mitochondrial dynamics, enhances mitochondrial function and cellular respiration, and has shown efficacy in reducing brain and cardiac damage in rats suffering from cardia...
T1677 Montelukast Singular Leukotriene Receptor , Lipoxygenase , LTR
Montelukast (Singular) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver injury...
T4612 NS309 EGFR , Potassium Channel , HER
NS309 is a nonselective activator of small- and intermediate-conductance Ca2+-activated K+ (SK/KCa2 and IK/KCa3.1) channels (EC50s range from 0.12-1.2 µM for SK channels and 10-90 nM for IK channels). It can also activat...
T1101 Minocycline hydrochloride Minocycline HCl HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
Minocycline hydrochloride (Minocycline HCl) is a tetracycline antibiotic with excellent absorption and tissue penetration that is used for several bacterial infections as well as treatment of acne. Minocycline hydrochlor...
T1677L Montelukast sodium MK0476 Leukotriene Receptor , LTR
Montelukast sodium (MK0476) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver i...
T1057 Azilsartan TAK-536 RAAS
Azilsartan (TAK-536) is an Angiotensin 2 Receptor Blocker. The mechanism of action of azilsartan is as an Angiotensin 2 Type 1 Receptor Antagonist. The physiologic effect of azilsartan is by means of Decreased Blood Pres...
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