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Montelukast

Catalog No. T1677 CAS 158966-92-8

Synonyms: Singular, 孟鲁司特

Montelukast is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver injury.

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Montelukast, CAS 158966-92-8

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	Singular, 孟鲁司特
Molecular Weight	586.19
Formula	C35H36ClNO3S
CAS No.	158966-92-8

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

H2O: 1.7 mM

DMSO: 170.6 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Zhang YJ, et al. Acta Pharmacol Sin. 2004 Oct;25(10):1341-6.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Metabolism Compound Library Lipid Metabolism Compound Library Anti-Metabolism Disease Compound Library Drug Repurposing Compound Library Bioactive Compound Library Clinical Compound Library

Related Products

Related compounds with same targets

Zafirlukast 5-O-Demethylnobiletin MK-571 sodium CGP 35949 ABT-080 L 674573 SR 2640 hydrochloride LY255283

Dose Conversion

You can also refer to dose conversion for different animals. More

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Molecular Weight Calculator

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Mass of a compound required to prepare a solution of known volume and concentration
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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
Enter 10 into the Volume box and select the correct unit (milliliter)
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The answer of 19.713 mg appears in the Mass box

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Calculator the dilution required to prepare a stock solution

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The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
Enter 20 into the Volume (final) box and select the correct unit (milliliter)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Montelukast 158966-92-8 G蛋白偶联受体代谢免疫与炎症 Leukotriene Receptor Lipoxygenase LTR intestinal COVID-19 Singular asthma Cysltr1 liver icardiac ischemia–reperfusion inhibit MK-0476 damage cysteinyl leukotriene antioxidant Inhibitor MK0476 MK 0476 injury inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.