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Search Results for " hek-293 "

20

Compounds

Cat No. Product Name Synonyms Targets
TN6791 Palvanil Hexadecanamide TRP/TRPV Channel
Palvanil (Hexadecanamide) is a fast desensitizing agonist of TRPV1. it may be promising agents in the therapy of IBS since it modulates intestinal motility and reduces visceral pain.
TN4417 Larixyl acetate Others
Larixyl acetate is a bioactive chemical.
T8959 OS-3-106 Dopamine Receptor
OS-3-106 is a novel arylamide phenylpiperazines, as partial agonists at the D3R in the adenylyl cyclase inhibition assay.
T5345 V-9302 Others
V-9302 (V9302) is a competitive antagonist of transmembrane glutamine flux that selectively and potently targets the amino acid transporter ASCT2 (IC50: 9.6 uM).
T50005 Sertaconazole Antifungal
Sertaconazole is a broad-spectrum antifungal.
T8528 AC1903 TRP/TRPV Channel
AC1903 is a specific inhibitor of TRPC5 channel, and has been shown to suppress severe proteinuria and prevent podocyte loss.
T0031L2 Ziprasidone Geodon,Zeldox,CP-88059 Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Norepinephrine , Histamine Receptor
Ziprasidone (Geodon) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity.
T3520 Setipiprant KYTH-105,ACT-129968 GPR , Prostaglandin Receptor
Setipiprant (ACT-129968) is an orally available, selective CRTH2 antagonist (IC50: 6.0 nM). CRTH2 is a G protein-coupled receptor for prostaglandin (PGD2). PGD2 is produced by the mast cells and is a key mediator in vari...
T6665 Sertaconazole nitrate FI-7045,Ginedermofix,FI7056,Ertaczo Antibiotic , Antifungal
Sertaconazole nitrate (FI-7045), a topical broad-spectrum antifungal, is developed to supply an additional agent for the treatment of superficial cutaneous and mucosal infections.
T0031 Ziprasidone hydrochloride monohydrate CP 88059 Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Norepinephrine , Histamine Receptor
Ziprasidone hydrochloride monohydrate (CP 88059) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of the antipsychotic activity.
T16569 Praliciguat IW-1973 Others , Guanylate cyclase
Praliciguat (IW-1973) stimulates sGC in HEK-293 cells (EC50: 197 nM). Praliciguat is an effective and orally active soluble guanylate cyclase stimulator. It also enhances NO signaling and acts as a vasodilator.
T6934 Pexmetinib ARRY-614 Tie-2 , p38 MAPK , Autophagy
Pexmetinib (ARRY-614) (ARRY-614) is a potent, orally bioavailable, dual p38 MAPK/Tie-2 inhibitor with IC50 of 4 nM/18 nM in a HEK-293 cell line. Phase 1.
T11076 Dooku1 Others
Dooku1 is an analog of Yoda1 and a selective antagonist of endogenous Piezo1 channels. Dooku1 inhibits Ca2+ entry induced by 2μMYoda1 with IC50 values of 1.3μM (in HEK 293 cells) and 1.5μM (in HUVEC). Dooku1 inhibits Yod...
T9018 JHU37160 JHU 37160 AChR
JHU37160 (JHU 37160) is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.9 nM and 3.6 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively. ...
T9019 JHU37152 JHU 37152 AChR
JHU37152 (JHU 37152) is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.8 nM and 8.7 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively. ...
T4967 NPS-2143 hydrochloride NPS-2143 HCL CaSR
NPS-2143 hydrochloride (NPS-2143 HCL) is a selective potent calcium ion-sensing receptor antagonist.
T1730 NPS-2143 SB262470,NPS 2143,SB 262470A Calcium Channel , CaSR
NPS-2143 (SB 262470A) is a novel potent and selective antagonist of Ca(2+) receptor.
T2092 Amitifadine hydrochloride DOV-21947 hydrochloride,EB-1010 hydrochloride Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine
Amitifadine hydrochloride (EB-1010 hydrochloride) is a triple reuptake inhibitor (TRI) or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI).
T14190 Alniditan Alnitidan 5-HT Receptor
Alniditan is a receptors agonist of 5-HT1B/1D in HEK 293 cells (IC50: 1.7 and 1.3 nM). For 5-HT1B/1D receptors, the pKi values are 8.96 and 9.40, respectively.
T15398 GNE-0946 Others
GNE-0946 is a potent and selective agonist of RORγ (EC50: 4 nM for HEK-293 cell).
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