elt — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0674	Lansoprazole	A-65006,AG-1749	Proton pump , Phospholipase , Antibacterial
	Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is fo...		Proton pump , Phospholipase , Antibacterial
T3S1888	Deltaline	Deltamine 6-acetate,Eldelin	Others
	Use of Deltaline (Eldelin) as versatile antidotes against poisoning of animals and humans.		Others
T7746	Eltoprazine dihydrochloride		Others
	Eltoprazine dihydrochloride is a drug that had previously been developed for aggression, has recently been investigated for L-DOPA-induced dyskinesia in animal models of Parkinson´s disease (PD) and in dyskinetic PD pati...		Others
T14997	Conteltinib	SY-707,CT-707	FAK , PYK2 , ALK
	Conteltinib (CT-707) is an enzyme inhibitor with antitumor activity targeting FAK, ALK, and Pyk2.Conteltinib exhibits significant inhibition of FAK, overcomes hypoxia-mediated sorafenib resistance in hepatocellular carci...		FAK , PYK2 , ALK
T5S1025	Picfeltarraenin IA	Picfeltarraenin A	AChE
	1. Picfeltarraenin IA (Picfeltarraenin A), IB, IV, X, XI are stronger AChE inhibitions than the known AChE inhibitor Tacrine.		AChE
T1463	Ramelteon	TAK-375	Melatonin Receptor , MT Receptor
	Ramelteon (TAK-375) is a Melatonin Receptor Agonist. The mechanism of action of ramelteon is as a Melatonin Receptor Agonist.		Melatonin Receptor , MT Receptor
T5186	Oseltamivir acid	GS 4071,oseltamivir carboxylate,Ro 64-0802	Influenza Virus , Drug Metabolite
	Oseltamivir acid (GS4071) is a potent influenza virus neuraminidase inhibitor and the prodrug of GS4071.		Influenza Virus , Drug Metabolite
T12877L	Seltorexant	JNJ-42847922	OX Receptor
	Seltorexant (JNJ-42847922) crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain. Seltorexant is a high-affinity and selective orexin-2 receptor antagonist (pKi: 8.0 and 8.1 for human a...		OX Receptor
T60663L	Oseltamivir acid methyl ester hydrochloride		Others
	Oseltamivir acid methyl ester hydrochloride is a precursor form of oseltamivir acid. Oseltamivir acid methyl ester is converted to oseltamivir acid converted by carboxylesterase 1 (CES1).		Others
T3495	Tasimelteon	VEC-162,BMS-214778	Melatonin Receptor , MT Receptor
	Tasimelteon (BMS-214778) is a melatonin receptor agonist that is used for the treatment of non-24 hour sleep-wake disorder in blind individuals.		Melatonin Receptor , MT Receptor
T11766L	Eltanexor	ONO-7706,KPT-8602,ATG-016	Others
	Eltanexor (ONO-7706) is an orally active exportin-1 (XPO1) inhibitor. It has effective anti-leukemic activity. Eltanexor inhibits XPO1-dependent nuclear export (EC50=60.9 nM) by directly targeting XPO1. Eltanexor causes ...		Others
T20166	Deltorphin	Deltorphin A,Dermenkephalin	Opioid Receptor
	Deltorphin (Dermenkephalin) is Isolated from the skin of Phyllomedusa Sauvage. It also has an affinity to the opioid receptor.		Opioid Receptor
T7637	Deltorphin I	Deltorphin 1,Deltorphin I(TFA),Deltorphin C	Opioid Receptor
	Deltorphin I is an agonist of δ-opioid receptor.		Opioid Receptor
T20754	Deltamethrin	Butoss,RU-22974,Esbecythrin,K-Othrin,Decamethrin,RU 22974	Others
	Deltamethrin (RU 22974), a neurotoxic pyrethroid insecticide, produces a reversible sequence of motor symptoms in rats involving hind limb rigidity and choreoathetosis.Deltamethrin is globally used in crop protection, co...		Others
T6462	Deltarasin		PDE , Ras
	Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.		PDE , Ras
T7498	Eltoprazine hydrochloride	DU 28853 hydrochloride	5-HT Receptor
	Eltoprazine hydrochloride (DU 28853 hydrochloride) is a partial agonist at serotonin 5-HT1A, 5-HT1B, and 5-HT2B receptors (Ki value of 40, 52, and 81 nM, respectively).		5-HT Receptor
T27254	Eltenac	B78820,B 78820,B-78820,BY-820,BY 820,BY820
	Eltenac, a cyclooxygenase (COX) inhibitor, is used potentially for the treatment of pain.
T4S1024	Picfeltarraenin IB		Others , AChE
	1. Picfeltarraenin IB and Picfeltarraenin IA displayes no cytotoxic activity in vitro human tumor cell line panel.		Others , AChE
T7639	Deltorphin 2	Deltorphin 2(TFA),[D-Ala2]-Deltorphin II	Opioid Receptor
	Deltorphin 2 ([D-Ala2]-Deltorphin II) is an agonist of δ opioid receptor with an IC50 of 1 nM.		Opioid Receptor
T10652	Vimseltinib	DCC-3014	c-Fms , CSF-1R , c-Kit
	Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor (IC50s: <0.01 μM and 0.1-1 μM).		c-Fms , CSF-1R , c-Kit