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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T13368 | YLF-466D | C24 | AMPK |
YLF-466D (C24) is a newly developed AMPK activator, which inhibits platelet aggregation. | |||
T38291 | C24 Phytosphingosine (t18:0/24:0) | ||
C24 Phytosphingosine (t18:0/24:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis. C24 Phytosphingosine (t... | |||
T35810 | C24 dihydro Ceramide (d18:0/24:0) | Cer(d18:0/24:0) | |
C24 dihydro Ceramide is a sphingolipid that has been found in the stratum corneum of human skin.[1] It is found in higher concentrations in female sebum compared to male sebum.[2] C24 dihydro Ceramide levels positively c... | |||
T38284 | C24 dihydro 1-Deoxyceramide (m18:0/24:0) | C24 dihydro 1-Deoxyceramide (m18:0/24:0) | |
C24 dihydro 1-Deoxyceramide (m18:0/24:0) is a very long-chain atypical ceramide containing a 1-deoxysphinganine backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alan... | |||
T38283 | Tetracosanoyl-sulfatide | C24 3'-sulfo Galactosylceramide (d18:1/24:0) | |
Tetracosanoyl-sulfatide is an endogenous sulfated glycolipid, which are also known as sulfatides . Tetracosanoyl-sulfatide is the major sulfatide in mature myelin in the central and peripheral nervous systems. Levels of ... | |||
T38285 | C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) | C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) | Others |
C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) is the predominant sulfate analog in the mature myelin sheath. C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) interacted with C-type lectin and immunoglobulin-like... | |||
T1845 | B-Raf IN 1 | Raf | |
B-Raf IN 1 is a B-Raf (IC50: 24 nM) and c-Raf (IC50: 25 nM) inhibitor. | |||
T10775 | c-Fms-IN-2 | c-Fms | |
c-Fms-IN-2 is an inhibitor of c-FMS kinase (IC50 = 24 nM). | |||
T21448 | Abafungin | Bay w 6341,UNII-11DI31LWXF | Others |
Abafungin (Bay w 6341) is an antifungal agent with a broad-spectrum. | |||
T14363 | AZ-23 | AZ 23,AZ23 | Trk receptor |
AZ-23 is an inhibitor of ATP-competitive and Trk kinase A/B/C. For TrkA, TrkB, FGFR1, Flt3, Ret, MuSk, Lck, the IC50s values are 2 nM, 8 nM, 24 nM, 52 nM, 55 nM, 84 nM, 99 nM, respectively. | |||
T11125 | Durlobactam sodium salt | ETX2514 sodium salt | Antibacterial |
Durlobactam sodium salt (ETX2514 sodium salt) is an inhibitor of β-lactamase with IC50 values of 4 nM, 14 nM, and 190 nM for Class A KPC-2, Class C AmpC, and Class D OXA-24, respectively. Durlobactam sodium salt can be u... | |||
T5234 | Glycoursodeoxycholic acid | Ursodeoxycholylglycine,GUDCA | Others , Endogenous Metabolite |
Glycoursodeoxycholic acid (Ursodeoxycholylglycine) is an acyl glycine and a bile acid-glycine conjugate. It is a secondary bile acid produced by the action of enzymes existing in the microbial flora of the colonic enviro... | |||
T1415 | Gemfibrozil | CI-719,Jezil,Decrelip,Lopid | P450 , Adrenergic Receptor , PPAR |
Gemfibrozil (CI-719) interacts with peroxisome proliferator-activated receptors (PPARalpha) resulting in PPARalpha-mediated stimulation of fatty acid oxidation and an increase in lipoprotein lipase (LPL) synthesis. Gemfi... | |||
T1661 | Crizotinib | PF-02341066 | c-Met/HGFR , ROS , ALK , Autophagy , ROS Kinase |
Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor. | |||
T3641 | NVP-BAW2881 | BAW2881 | Raf , VEGFR , Bcr-Abl |
NVP-BAW2881 (BAW2881) is a potent and selective VEGFR inhibitor (vascular endothelial growth factor receptor tyrosine kinase inhibitor) with activity to inhibit chronic and acute skin inflammation. | |||
T10167 | 5-Dehydroepisterol | Others | |
5-Dehydroepisterol is an episterol derivative with anti-fungal activities. It can be formed by C-5 sterol desaturase and converted into 24-methylenecholesterol by 7-dehydrocholesterol reductase. | |||
T35979 | Benastatin C | ||
Benastatin C is a polyketide synthase-derived benastatin that has been found inStreptomycesand has diverse biological activities.1,2It inhibits glutathione S-transferase (GST; IC50= 24 μg/ml for the rat liver enzyme).2Be... | |||
T79354 | CDK9-IN-24 | CDK | |
CDK9-IN-24 (compound 21a) is a potent and selective inhibitor of CDK9 that exhibits a pronounced inhibitory impact on tumor proliferation. It impedes cell growth and triggers apoptosis via the downregulation of Mcl-1 and... | |||
T36961 | Malformin C | ||
Malformin C is a natural fungus-derived bicyclic pentapeptide that has antibacterial properties, particularly against species of Bacillus. Malformin C potently blocks the ability of bleomycin to induce G2 arrest in human... | |||
T36251 | DP-C-4 | ||
DP-C-4 is a Cereblon-based dual PROTAC for simultaneous degradation of EGFR and PARP[1]. DP-C-4 (1-50 μM; 24 hours) has degradation effects on EGFR and PARP simultaneously in a dose-dependent manner in SW1990 cells[1]. [... |