Search Result

Search Results for " bg "

Targets

Compounds

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T17117	Tonapofylline	BG 9928	Adenosine Receptor
	Tonapofylline is an orally active and selective antagonist of the A1 adenosine receptor (Ki: 7.4 nM for human A1). Tonapofylline can be used in studies about heart failure.		Adenosine Receptor
T40322	BG dimer
	BG dimer is a molecular dimer organic luminogen with aggregation-induced emission.
T5519	Bivalirudin	BG-8967,Hirulog-1	Thrombin
	Bivalirudin (BG-8967) is a reversible inhibitor of α- and ζ-thrombin (Kis = 2.56 and 1.84 nM, respectively), enzymes that exhibit high fibrinogen-clotting activities.		Thrombin
T19841	Tribenoside	Glyvenol,Glyvenal,Ba 2140,BG-356,Glivenol,TBGF	Others
	Tribenoside (BG-356) is a vasoprotectant with mild anti-inflammatory, analgesic, and wound healing properties.		Others
T2294	BG45		Apoptosis , HDAC
	BG45 is an HDAC I type inhibitor with IC50 of 289 nM, 2.0 μM, 2.2 μM and >20 μM for HDAC3/1/2/6 in cell-free assays, respectively.		Apoptosis , HDAC
T26786	BG14	BG 14,BG-14
	BG14 is a probe for chemo-optical modulation of epigenetically regulated transcription (COMET). It enables high-resolution, optical control of epigenetic mechanisms and photochromically inhibits human histone deacetylase...
T26787	BG47	BG-47,BG 47
	BG47 is a probe for chemo-optical modulation of epigenetically regulated transcription (COMET). It enables high-resolution, optical control of epigenetic mechanisms and photochromically inhibits human histone deacetylase...
T26788	BG48	BG-48,BG 48
	BG48 is a probe of chemo-optical modulation of epigenetically regulated transcription (COMET). It enables high-resolution, optical control of epigenetic mechanisms and photochromically inhibits human histone deacetylases...
T27545	Hirugen	BG 8865,Hirudin dodecapeptide
	Hirugen is a derivative of hirudin, which is an anticoagulant protein found in leeches.
T78303	Baminercept	TT-47,BG 9924
	Baminercept (BG 9924), an IgG fusion protein targeting the lymphotoxin β receptor (LTβR-Ig), has potential applications in the study of various autoimmune diseases, such as primary Sjögren's syndrome (SS) and rheumatoid ...
T26565	Adentri	BG-9719,BG9719,BG 9719,CVT124,CVT-124,CVT 124
	Adentri is a novel antagonist of adenosine A1 receptor with unique diuretic activity.
T20104	C.I. 37545	NSC 37618,Brenthol FO,Naphtanilide BG,Acna Naphthol BG,Azoic dyes
	C.I. 37545 is also known as Azoic dyes. C.I. 37545 is impregnated cotton with an alkaline solution of β-naphthol, then treated it with a diazo solution obtained from aniline, a toluidine, xylidine, naphthylamine, aminoaz...
T78298	Alefacept	LFA 3TIP,Human LFA 3IgG fusion protein,BG 9273
	Alefacept (BG 9273), a fusion protein combining human lymphocyte function-associated antigen 3 with immunoglobulin 1, is utilized in the research of chronic plaque psoriasis [1].
T33600	Naxifylline	CVT 124,CVT-124,CVT124,BG9719
	Naxifylline is an A1 adenosine receptor antagonist that promotes urine volume to prevent the decline in renal function observed during diuretic therapy for the treatment of edema associated with congestive heart failure.
T4618	BGG463	K 0859	Bcr-Abl , CDK
	BGG463 (K 0859) can inhibit c-ABL-T334I, BCR-ABL and BCR-ABL-T315I variants with a 50% inhibitory concentration (IC50) of 0.25 μM, 0.09 μM and 0.590 μM, respectively.		Bcr-Abl , CDK
T4502	BISMUTH SUBGALLATE	Dermatol Puder,Bismuth Gallate	Others
	Bismuth subgallate (Dermatol Puder) is an astringent and antiseptic and is applied to skin diseases such as eczema.		Others
T10531	BGB-102	JNJ-26483327	EGFR , VEGFR , FLT , Src
	BGB-102 (JNJ-26483327) is a kinase inhibitor targeting FLT3 and YES1 and an antagonist targeting EGFR and VEGFR3, which may be useful in the study of macular degeneration and diseases associated with genetic disorders an...		EGFR , VEGFR , FLT , Src
T3649	BGP-15	BGP15,BGP-15 2HCl	PARP
	BGP-15 (BGP-15 2HCl) is a PARP inhibitor with protecting effect after ischemia-reperfusion injury.		PARP
T6072	BGT226 maleate	BGT226,NVP-BGT226 (maleate),NVP-BGT226	Apoptosis , PI3K , mTOR , Autophagy
	BGT226 maleate (NVP-BGT226) is a class I PI3K/mTOR inhibitor for PI3Kα/β/γ (IC50: 4/63/38 nM) .		Apoptosis , PI3K , mTOR , Autophagy
T8993L	BGC-20-1531 hydrochloride(1186532-61-5 free base)	BGC-20-1531 hydrochloride,GTPL3380 hydrochloride,AP-1531 hydrochloride	Prostaglandin Receptor
	BGC-20-1531 hydrochloride(1186532-61-5 free base) (GTPL3380 hydrochloride) is a EP4 antagonist for the treatment of acute migraine.		Prostaglandin Receptor
T6072L	BGT226	BGT226 free base,NVP-BGT226	PI3K , mTOR , Autophagy
	BGT226 (NVP-BGT226) is a novel dual PI3K / mTOR inhibitor, it acts on PI3K α/β/γ with IC50 of 4 nM / 63 nM / 38 nM, respectively.		PI3K , mTOR , Autophagy
T38538	BGN3
	BGN3 is a good substrate for the SNAP- tag and H 5 enzymes. The activities of SNAP- tag and H 5 enzymes on BGN3 are reasonable (IC 50 = 15.6 and 23.5 μM, respectively).
T39468	PYBG-TMR
	PYBG-TMR, a fluorochrome, serves as a dye that specifically and efficiently labels genetically encoded SNAP-tags in live cells.
T40788	PYBG
	PYBG serves as a flexible precursor for facile conjugation with diverse fluorescent dyes using 'Click chemistry' and Sonogashira coupling reactions.
T23786	BGB659	BGB 659,BGB-659
	BGB659 is effective inhibitor of RAF.
T74238	BGTC
	BGTC, a non-amino acid cationic lipid, serves as a vehicle for nucleic acid delivery [1].
T32369	KBG 4
	KBG 4 is a bioactive chemical.
T8993	BGC201531	AP-1531,GTPL3380,BGC-20-1531	Prostaglandin Receptor
	BGC201531 (AP-1531) is a EP4 antagonist for the treatment of acute migraine.		Prostaglandin Receptor
T23787	BGT1-IN-9	BGT1 IN 9,BGT1 inhibitor 9,BGT1IN9,BGT1-inhibitor-9
	BGT1-IN-9 is an M1 muscarinic agonist.
T39469	PYBG-BODIPY
	PYBG-BODIPY, a fluorochrome dye, specifically and efficiently labels genetically encoded SNAP-tags in live cells, serving its role as a targeted marker.
T79156	(R)-SKBG-1		Androgen Receptor
	(R)-SKBG-1 is an inhibitor of the RNA-binding protein NONO, effectively downregulating androgen receptor expression by targeting both AR-FL mRNA and AR-V7 mRNA, with inhibition concentration (IC50) values of 3.1 μM and 5...		Androgen Receptor
T22044	BGC 20-761
	BGC20-761 is a selecvtive 5-HT6 and dopamine receptor antagonist (human receptor K i values: 5-HT6 (20 nM), 5-HT2A (69 nM), D2 (140 nM). BGC20-761 is a tryptamine analog with a high affinity for 5-HT(6) receptors, that c...
T62485	FabG1-IN-1
	FabG1-IN-1 (Compound 29) is a potent inhibitor of MabA (FabG1) (IC50: 38 μM).
T63316	BGC-20-1531 free base
	BGC-20-1531 (PGN 1531) free base is a selective and potent prostaglandin EP4 receptor antagonist (pKB: 7.6) that exhibits potential for migraine research.
T27987	MCPBG	m-Chlorophenylbiguanide
	mCPBG is a potent high affinity agonist of 5-HT3 receptor.
T73381	BGB-8035
	BGB-8035 is an orally administered, highly selective inhibitor of Bruton's tyrosine kinase (BTK), exhibiting IC50 values of 1.1 nM for BTK, 99 nM for TEC, and 621 nM for EGFR. It demonstrates antitumor and anti-arthritis...
T69268	BGC-638
	BGC-638, an analogue of BGC-945, is a thymidylate synthase inhibitor specifically transported into α-folate receptor (α-FR)Â–overexpressing tumors.
T9543	Syk Inhibitor II hydrochloride		Others
	The impact of spleen tyrosine kinase (Syk) signaling might be prominent in lupus because (i) Syk is a shared downstream signaling molecule among circulating immune complex, LPS, and (1→3)-β-D-glucan (BG), and (ii) all of...		Others
T76825	Ruplizumab
	Ruplizumab (BG 9588), a humanized monoclonal IgG1κ antibody targeting CD40L (TNF Receptor), holds promise for research in systemic lupus erythematosus disease [1].

Compounds

Tonapofylline

T17117

Synonym: BG 9928

Target: Adenosine Receptor

Synonym: BG-8967,Hirulog-1

Target: Thrombin

Tribenoside

T19841

Synonym: Glyvenol,Glyvenal,Ba 2140,BG-356,Glivenol,TBGF

Target: Apoptosis, HDAC

Synonym: BG 8865,Hirudin dodecapeptide

Target:

Baminercept

T78303

Synonym: TT-47,BG 9924

Target:

Adentri

T26565

Synonym: BG-9719,BG9719,BG 9719,CVT124,CVT-124,CVT 124

Target:

C.I. 37545

T20104

Synonym: NSC 37618,Brenthol FO,Naphtanilide BG,Acna Naphthol BG,Azoic dyes

Target:

Alefacept

T78298

Synonym: LFA 3TIP,Human LFA 3IgG fusion protein,BG 9273

Target:

Naxifylline

T33600

Synonym: CVT 124,CVT-124,CVT124,BG9719

Synonym: Dermatol Puder,Bismuth Gallate

Target: Others

BGB-102

T10531

Synonym: JNJ-26483327

Target: EGFR, VEGFR, FLT, Src

BGP-15

T3649

Synonym: BGP15,BGP-15 2HCl

Target: PARP

BGT226 maleate

T6072

Synonym: BGT226,NVP-BGT226 (maleate),NVP-BGT226

Target: Apoptosis, PI3K, mTOR, Autophagy

BGC-20-1531 hydrochloride(1186532-61-5 free base)

T8993L

Synonym: BGC-20-1531 hydrochloride,GTPL3380 hydrochloride,AP-1531 hydrochloride

Target: Prostaglandin Receptor

BGT226

T6072L

Synonym: BGT226 free base,NVP-BGT226

Target: PI3K, mTOR, Autophagy

Synonym: BGB 659,BGB-659

Synonym: AP-1531,GTPL3380,BGC-20-1531

Target: Prostaglandin Receptor

BGT1-IN-9

T23787

Synonym: BGT1 IN 9,BGT1 inhibitor 9,BGT1IN9,BGT1-inhibitor-9

Target: Androgen Receptor

BGC-20-1531 free base

Synonym: m-Chlorophenylbiguanide

Syk Inhibitor II hydrochloride

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01278	Apolipoprotein H/APOH Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Apolipoprotein H/APOH Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.7 kDa and the accession number is A0A384NKM6.
TMPY-03418	Biglycan Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Biglycan Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66.5 kDa and the accession number is P28653.
TMPK-01328	Apolipoprotein H/APOH Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Apolipoprotein (apo)H (also known as beta 2 glycoprotein-I) is a glycoprotein synthesized by liver cells and it is present in the blood associated with plasma lipoproteins. APOH displays a genetically determined structur...
TMPY-05033	5T4/TPBG Protein, Human, Recombinant (aa 60-345, His)	Human	HEK293 Cells
	Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adul...
TMPY-06214	5T4/TPBG Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adul...
TMPH-03392	5T4/TPBG Protein, Rat, Recombinant (His & SUMO)	Rat	E. coli
	May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. 5T4/TPBG Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli ex...
TMPH-02107	SH3BGRL Protein, Human, Recombinant (GST & His)	Human	E. coli
	SH3BGRL Protein, Human, Recombinant (GST & His) is expressed in E. coli.
TMPJ-01153	5T4/TPBG Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	5T4/TPBG Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-80 KDa and the accession number is Q4R8Y9.
TMPJ-00268	5T4/TPBG Protein, Human, Recombinant (Avi & His), Biotinylated	Human	HEK293 Cells
	5T4/TPBG Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 60-90 KDa and the accession number is Q13641.
TMPK-00270	TPBG/5T4 Protein, Human, Recombinant (His & Avi), FITC-Labeled	Human	HEK293 Cells
	The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR...
TMPK-00271	TPBG/5T4 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR...
TMPY-01256	TBG Protein, Human, Recombinant (His)	Human	HEK293 Cells
	TBG Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.5 kDa and the accession number is P05543.
TMPH-02436	5T4/TPBG Protein, Cynomolgus, Recombinant (E. coli, His & Myc)	Cynomolgus	E. coli
	May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. 5T4/TPBG Protein, Cynomolgus, Recombinant (E. coli, His & Myc) is expresse...
TMPY-01240	TBG Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	TBG Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.2 kDa and the accession number is Q3UEL9.
TMPH-01435	Hemoglobin subunit gamma-1/HBG1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Gamma chains make up the fetal hemoglobin F, in combination with alpha chains. Hemoglobin subunit gamma-1/HBG1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag...
TMPH-00564	FabG Protein, E. coli, Recombinant (His & Myc)	E. coli	E. coli
	Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
TMPY-06191	5T4/TPBG Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adul...
TMPJ-01297	WIBG Protein, Human, Recombinant (His)	Human	E. coli
	Partner of Y14 and Mago (WIBG) is a key regulator of the Exon Junction Complex (EJC). EJC is a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs, is a positional landmarker for ...
TMPY-06317	5T4/TPBG Protein, Human, Recombinant (aa 1-355, His)	Human	HEK293 Cells
	Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adul...
TMPJ-00269	5T4/TPBG Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	5T4/TPBG Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 80-110 KDa and the accession number is Q13641.
TMPY-04506	A1BG Protein, Human, Recombinant (His)	Human	HEK293 Cells
	A1BG Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 53.4 kDa and the accession number is P04217-1.
TMPH-02437	5T4/TPBG Protein, Cynomolgus, Recombinant (His & Myc)	Cynomolgus	HEK293 Cells
	May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. 5T4/TPBG Protein, Cynomolgus, Recombinant (His & Myc) is expressed in HEK2...