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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11184 | EML4-ALK kinase inhibitor 1 | EML4 ALK kinase inhibitor 1,EML4-ALK kinase inhibitor 1 | ALK |
EML4-ALK kinase inhibitor 1 (EML4 ALK kinase inhibitor 1) is a potent oral active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM. | |||
T39764 | ALK2-IN-4 | ALK2-IN-4 | |
ALK2-IN-4, a highly effective ALK2 inhibitor. | |||
T2251 | NVP-TAE 684 | TAE684 | Apoptosis , ALK |
NVP-TAE 684 (TAE684) is a excellently effective and specific ALK inhibitor(IC50=3 nM). | |||
T67699L | ALK/ROS1 inhibitor 2e HCL | (R)-1-(2-((2-methoxy-4-(piperazin-1-yl)phenyl)amino)pyridin-4-yl)-N-(4-(trifluoromethoxy)benzyl)piperidine-3-carboxamide hydrochloride(2365497-12-5 Free base) | Apoptosis |
ALK/ROS1 inhibitor 2e HCL possesses anti-apoptotic, anti-proliferative and anti-tumour activities. | |||
T40065 | ALK2-IN-4 succinate | ALK2-IN-4 succinate | |
ALK2-IN-4 succinate is a robust and effective inhibitor of ALK2. | |||
T2641 | KRCA-0008 | KRCA 0008,KRCA0008 | ACK , ALK |
KRCA-0008 is an effective and specific ALK/Ack1 inhibitor (IC50: 12/4 nM); displays drug-like properties without hERG liability. | |||
T22324 | Ensartinib hydrochloride | Ensartinib dihydrochloride,X-396 dihydrochloride | Others , Trk receptor , c-Met/HGFR , ALK |
Ensartinib hydrochloride (X-396 dihydrochloride) is a potent new-generation ALK inhibitor with high activity against CNS metastases and a broad range of known crizotinib-resistant ALK mutations. It potently inhibits both... | |||
T15612 | JH-VIII-157-02 | Microtubule Associated , ALK | |
JH-VIII-157-02 is an inhibitor of ALK and inhibits echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) with IC50s of 2 nM for EML4-ALK G1202R, EML4-ALKwt, EML4-ALK C1156Y, EML4-ALK F1174L, and EML4-ALK F1174L... | |||
T3550 | X-376 | Ensartinib,X-396 | c-Met/HGFR , ALK |
X-376 (Ensartinib) is an orally available small molecule inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with potential antineoplastic activity. Upon oral administration, X-396 binds to and inh... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05483 | ALK-4/ACVR1B Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
ALK-4/ACVR1B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 38.1 kDa and the accession number is P36896-1. | |||
TMPY-01293 | ALK-4/ACVR1B Protein, Human, Recombinant (His) | Human | HEK293 Cells |
ALK-4/ACVR1B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13 kDa and the accession number is P36896-1. | |||
TMPK-00305 | TGFBR1 Protein, Human, Recombinant (mFc & Avi) | Human | HEK293 Cells |
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the sup... | |||
TMPY-03300 | ALK-4/ACVR1B Protein, Rat, Recombinant (hFc) | Rat | HEK293 Cells |
ALK-4/ACVR1B Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 38.4 kDa and the accession number is P80202. | |||
TMPY-03100 | ALK-4/ACVR1B Protein, Rhesus, Recombinant (hFc) | Rhesus | HEK293 Cells |
ALK-4/ACVR1B Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 38.2 kDa and the accession number is I2CYX8. | |||
TMPY-00444 | ALK-4/ACVR1B Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
ALK-4/ACVR1B Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 38.4 kDa and the accession number is Q3TZF1. | |||
TMPK-00767 | SLPI Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Elafin and SLPI (secretory leucocyte protease inhibitor) have multiple important roles both in normal homoeostasis and at sites of inflammation. These include antiprotease and antimicrobial activity as well as modulation... | |||
TMPK-00924 | SLPI Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Elafin and SLPI (secretory leucocyte protease inhibitor) have multiple important roles both in normal homoeostasis and at sites of inflammation. These include antiprotease and antimicrobial activity as well as modulation... | |||
TMPJ-01178 | TGFBR1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
TGF-beta RI, also called ALK-5, is an approximately 55 kDa type I transmembrane serine/threonine receptor kinase. In the presence of TGF-beta, TGF-beta RI forms a complex with, and is phosphorylated by, TGF-beta RII. Pho... | |||
TMPY-04366 | ALK-5 Protein, Human, Recombinant (aa 200-503, His & GST) | Human | Baculovirus Insect Cells |
ALK-5 Protein, Human, Recombinant (aa 200-503, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 62.6 kDa and the accession number is P36897-1. | |||
TMPY-05771 | ALK-5 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
ALK-5 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 36.87 kDa and the accession number is P36897-1. | |||
TMPY-01358 | ALK-5 Protein, Human, Recombinant (His & hFc) | Human | HEK293 Cells |
ALK-5 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 38.1 kDa and the accession number is P36897-1. | |||
TMPK-00306 | TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated | Human | HEK293 Cells |
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the sup... | |||
TMPJ-00864 | VEGF165 Protein, Human, Recombinant | Human | HEK293 Cells |
Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator... | |||
TMPY-00749 | FGF-2 Protein, Human, Recombinant | Human | E. coli |
FGF-2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16.5 kDa and the accession number is P09038-4. | |||
TMPK-00823 | VEGF165 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a... | |||
TMPY-04911 | VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated | Human,Cynomolgus | HEK293 Cells |
VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 23.1 kDa and the accession number is P15692-4. | |||
TMPY-02893 | NT5C3A/NT5C3 Protein, Human, Recombinant | Human | E. coli |
NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded prot... | |||
TMPK-00423 | CD45 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com... | |||
TMPK-00822 | VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled | Human | HEK293 Cells |
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a... | |||
TMPY-04754 | CASK Protein, Human, Recombinant | Human | Baculovirus Insect Cells |
CASK Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 102.1 kDa and the accession number is O14936-4. | |||
TMPY-01822 | PTK9 Protein, Human, Recombinant (His & GST) | Human | E. coli |
PTK9 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 57 kDa and the accession number is Q12792-4. | |||
TMPY-04471 | APEG1 Protein, Human, Recombinant (His) | Human | E. coli |
Striated muscle preferentially expressed protein kinase, also known as aortic preferentially expressed protein 1, APEG-1, SPEG and KIAA1297, is a protein that belongs to the protein kinase superfamily and CAMK Ser/Thr pr... | |||
TMPK-00424 | CD45 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com... | |||
TMPJ-00782 | Amyloid Precursor Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Amyloid precursor protein (APP) is a type I membrane protein with several isoforms due to alternative splicing, performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and... | |||
TMPY-00380 | ANTXR2 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
ANTXR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 57.4 kDa and the accession number is P58335-4. | |||
TMPJ-00410 | CD45R0 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CD45R0 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 80-120 KDa and the accession number is P08575-4. | |||
TMPJ-00233 | CD200R1/CRTR2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain ... | |||
TMPY-01117 | MRAP Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
MRAP (Melanocortin 2 Receptor Accessory Protein) is a Protein Coding gene. This gene encodes a melanocortin receptor-interacting protein. It belongs to the MRAP family. MRAP, which contains a single transmembrane domain,... | |||
TMPY-01033 | IL-32 Protein, Human, Recombinant (isoform alpha, His) | Human | HEK293 Cells |
IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathw... | |||
TMPY-05598 | Siglec-2/CD22 Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 Cells |
Siglec-2/CD22 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 103.7 kDa and the accession number is P20273-4. | |||
TMPJ-01333 | TEM8/ANTXR1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothel... | |||
TMPK-00702 | ANTXR2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
The Capillary Morphogenesis Gene 2 (CMG2) gene encodes an Anthrax toxin receptor (ANTXR2),ANTXR2/CMG2 was originally identified as a result of up-regulation during capillary morphogenesis of endothelial cells (ECs) cultu... | |||
TMPY-04565 | SRPK3 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
Serine / threonine-protein kinase SRPK3, also known as Muscle-specific serine kinase 1, Serine/arginine-rich protein-specific kinase 3, SR-protein-specific kinase 3, Serine / threonine-protein kinase 23, MSSK-1, SRPK3 an... | |||
TMPJ-01188 | CORO6 Protein, Human, Recombinant (His) | Human | E. coli |
Coronin 6, a newly identified member of the coronin family, is highly enriched at adult NMJs and regulates AChR clustering via modulating the interaction between receptors and the actin cytoskeletal network. Coronins are... | |||
TMPY-01823 | PTK9 Protein, Human, Recombinant | Human | E. coli |
PTK9 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 29 kDa and the accession number is Q12792-4. | |||
TMPY-00225 | CLEC9A Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
CLEC9A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.1 kDa and the accession number is Q8BRU4-4. | |||
TMPJ-01256 | Caspase-10 Protein, Human, Recombinant (His) | Human | E. coli |
Caspase-10 (CASP10) is a 521 amino acid protein member of the Cysteine-Aspartic Acid Protease (Caspase) family. CASP10 contains two DED (Death Effector) domains and is detectable in most tissues. CASP10 cleavage by Granz... | |||
TMPY-04563 | CASK Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
CASK Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 130 kDa and the accession number is O14936-4. | |||
TMPY-00119 | FLT1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
FLT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.1 kDa and the accession number is P17948-4. | |||
TMPY-01933 | CHI3L2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Chondrocyte protein 39 (YKL-39), also known as Chitinase 3-like 2 (CHI3L2), is a secretory protein of articular chondrocytes belonging to the glycosyl hydrolase 18 family. Its highest expression is in chondrocytes, follo... | |||
TMPY-00711 | CD45 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
CD45 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.1 kDa and the accession number is P08575-4. | |||
TMPK-01356 | SIRP alpha V4 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPK-01362 | SIRP alpha V4 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... |