a-factor — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T28869	Streptomyces A-Factor	A-Factor (Lactone)
	Streptomyces A-Factor is a microbial hormone found in Streptomyces griseus. A-factor triggers streptomycin biosynthesis and cell differentiation by binding a repressor-type receptor protein (ArpA) and dissociating it fro...
T31742	Factor 390 A	F390-A,F390A,P-5-(S)-N-(N-(1-Oxo-2-(phosphonooxy)propyl)-L-gamma-glutamyl)-L-glutamate,F390 A
	Factor 390 A is a phosphodiester between AMP & methanogen factor 420.
TQ0131	Rocaglamide	Rocaglamide A,Roc-A	HSP , NF-κB , PERK
	Rocaglamide (Roc-A), isolated from the genus Aglaia, can be used to treat coughs, injuries, asthma, and inflammatory skin diseases. It is a potent inhibitor of NF-κB activation in T-cells.		HSP , NF-κB , PERK
T5687	WITHAFERIN A		Ferroptosis , NF-κB
	WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/or cancer.		Ferroptosis , NF-κB
T3777	Praeruptorin A	(+)-Praeruptorin A	CaMK , NF-κB
	Praeruptorin A ((+)-Praeruptorin A) has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or...		CaMK , NF-κB
T3877	Esculentoside A		NF-κB , COX
	Esculentoside A can suppress inflammatory responses in LPS-induced ALI through inhibition of the NF-κB and mitogen-activated protein kinase signaling pathways. Esculentoside A may be useful for the treatment of autoimmun...		NF-κB , COX
T6S1966	Curculigoside	Curculigoside A	Antioxidant , NF-κB , JAK , STAT
	1. Curculigoside (Curculigoside A) can prevent bone loss , improve osteogenesis and inhibit osteoclastogenesis of hAFSCs, suggesting its potential use to regulate hAFSC osteogenic differentiation for treating bone disord...		Antioxidant , NF-κB , JAK , STAT
T11373	GCN2-IN-1	A-92	Others
	GCN2-IN-1 (A-92) is an effective GCN2 inhibitor and can be used in research on the treatment of cancer as a chemotherapeutic agent.		Others
T6S1597	Mulberroside A		TNF , Tyrosinase , Interleukin
	1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberroside A resulted in enhanced inhibition of...		TNF , Tyrosinase , Interleukin
T2913	Schisantherin A	Schisanwilsonin H,Gomisin-C,Wuweizi ester-A,Schizantherin-A,Arisanschinin K	NF-κB
	Schisantherin A (Wuweizi ester-A) is a dibenzocyclooctadiene lignan isolated from the fruit of Schisandra sphenanthera, has been used as an antitussive, tonic, and sedative agent.		NF-κB
TP1106L	α-Factor Mating Pheromone, yeast acetate	Mating Factor α acetate,α-Factor Mating Pheromone, yeast acetate(59401-28-4 free base)	Others
	α-Factor Mating Pheromone, yeast acetate (Mating Factor α acetate) is a peptide of 13 amino acids secreted by Saccharomyces cerevisiae α cells.		Others
T2098	A 77-01	A77-01	ALK , TGF-beta/Smad
	A 77-01 is a potent inhibitor of TGF-(beta) type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM.		ALK , TGF-beta/Smad
TN2081	Maohuoside A		MAPK
	Maohuoside A promotes osteogenesis of rat mesenchymal stem cells via BMP and MAPK signaling pathways.		MAPK
T3031	A 83-01	ALK5 Inhibitor IV,A8301	ALK , TGF-beta/Smad
	A 83-01 (ALK5 Inhibitor IV) is an inhibitor of the TGF-β type I receptors ALK5, ALK4, and ALK7 (IC50=12/45/7.5 nM). A 83-01 promotes the reprogramming of mouse fibroblasts into iPSCs. A 83-01 can be used in organoid cult...		ALK , TGF-beta/Smad
T2921	Sinomenine hydrochloride	Sabianine A hydrochloride,Cucoline hydrochloride,Kukoline hydrochloride	Apoptosis , NF-κB , Opioid Receptor , Autophagy
	Sinomenine hydrochloride (Kukoline hydrochloride) is extracted from Sinomenium Acutum Rehderett Wilson.		Apoptosis , NF-κB , Opioid Receptor , Autophagy
T4288	HVEGF-IN-1		VEGFR
	hVEGF-IN-1 inhibits human VEGF-A translation and has antitumor activity.		VEGFR
T21445	Naphazoline	AK-Con,Naphcon-a,Clear Eyes,All Clear	Adrenergic Receptor
	Naphazoline (Naphcon-a) is a sympathomimetic compound with marked alpha adrenergic activity. Naphazoline can be used as a vasoconstrictor with a rapid action in reducing swelling when applied to mucous membrane.		Adrenergic Receptor
T2801	Aristolochic acid A	TR 1736,Aristolochin,Aristolochine,Aristolochic Acid I,Aristolochic Acid	Others , NF-κB
	Aristolochic acid A (TR 1736) is a compound of mutagenic, carcinogenic, and nephrotoxic compounds commonly found in the Birthwort (Aristolochiaceae) family of plants.		Others , NF-κB
T76360	a-Helical Corticotropin Releasing Factor (12-41)
	α-Helical Corticotropin Releasing Factor (12-41), a 30-amino-acid α-helical analogue of corticotropin releasing factor/hormone (CRF), is a hypothalamic hormone that promotes adrenocorticotrophic hormone (ACTH) secretion....
T76204	a-Helical Corticotropin Releasing Factor (9-41)
	α-Helical Corticotropin Releasing Factor (9-41) is a corticotropin releasing factor (CRF) antagonist that lowers plasma growth hormone (GH) levels in vivo [1] [2].