Home Tools
Log in
Cart

Search Result

Search Results for " serotonergic "

20

Compounds

Cat No. Product Name Synonyms Targets
T0137 Mirtazapine 6-Azamianserin,Org3770 Dopamine Receptor , 5-HT Receptor , Opioid Receptor , Adrenergic Receptor , Histamine Receptor
Mirtazapine (6-Azamianserin) is a tetracyclic antidepressant with a somewhat unique mechanism of action. Mirtazapine therapy can be associated with transient asymptomatic elevations in serum aminotransferase levels and h...
T13458 (Z)-Thiothixene Thiothixene,Navane,cis-Thiothixene Serotonin Transporter
(Z)-Thiothixene (Thiothixene) is an antagonist of serotonergic receptor.
T8438 4i CHEMBL1269981,5-HT3 antagonist-4i 5-HT Receptor
4i (CHEMBL1269981) is a 5-HT3 receptor antagonist,It modulates the serotonergic system.
T20828 Citalopram Cipram,Lu 10-171,Lu-10-171 Lu10-171 5-HT Receptor
Citalopram (Lu 10-171 is an orally active, selective serotonin reuptake inhibitor (SSRI), a selective 5-hydroxytryptamine reuptake inhibitor, and a racemic mixture of the S(+)-enantiomer (Escitalopram) and the R(-)-enant...
T60325 Viloxazine Emovit,Viloxazin 5-HT Receptor , Norepinephrine
Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activity towards 5-HT 2C receptors while acting as an antagonist for 5-HT 2...
T68090 Laprafylline Others
Laprafylline is a xanthine compound with inhibitory effects on bronchoconstriction in vivo and antitumor activity.Laprafylline acts as a competitive serotonergic antagonist at low concentrations, and inhibits constrictio...
T21011 Buspirone Buspirone free base,Ansial 5-HT Receptor
Buspirone (Buspirone free base) is an azaspiro compound which has a role as an anxiolytic drug, a sedative, a serotonergic agonist and an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor.
T21569 1-(1-Naphthyl) piperazine hydrochloride 1-naphthalen-1-ylpiperazine hydrochloride,1-(Naphthalen-1-yl)piperazine hydrochloride Others
1-(1-Naphthyl) piperazine hydrochloride (1-naphthalen-1-ylpiperazine hydrochloride) is a serotonergic ligand which could bind nonselectively with multiple serotonin (5-HT) receptors.
T4297 Flibanserin BIMT-17BS,Girosa,BIMT-17 Dopamine Receptor , 5-HT Receptor
Flibanserin (Girosa) is a serotonergic antidepressant used to treat hypoactive sexual desire disorder. Flibanserin has been associated with a low rate of minor serum aminotransferase elevations during treatment but has n...
T3386 Kaempferitrin Lespedin,Kaempferol,Lespenephryl,Lespenefril,Kaempferol 3,7-dirhamnoside cell cycle arrest , Glucokinase , IGF-1R
Kaempferitrin (Lespenephryl) has antidepressant-like effect related to the serotonergic system, principally 5-HT1A. Kaempferitrin exerts cytotoxic and antitumor effects against HeLa cells. Kaempferitrin stimulates glucos...
T1279 Vilazodone SB659746A,EMD 68843 5-HT Receptor , Serotonin Transporter
Vilazodone (SB659746A) is a selective serotonin (5-HT) reuptake inhibitor (SSRI) and a 5-HT-1A receptor partial agonist, with antidepressant and anti-anxiety activities. Vilazodone inhibits the reuptake of serotonin from...
T2395 Vortioxetine Lu AA 21004 5-HT Receptor , Serotonin Transporter
Vortioxetine (Lu AA 21004) is a serotonergic antidepressant used for major depression disorders. Vortioxetine has been associated with a low rate of minor serum aminotransferase elevations during treatment.
T4S1990 Carvacrol Karvakrol,O-Thymol,cymophenol Apoptosis , Others , Gamma-secretase , Endogenous Metabolite , Antifungal
1. Carvacrol (O-Thymol) presents anxiolytic effects. 2. 5-Isopropyl-2-methylphenol presents antinociceptive activity. 3. Carvacrol presents antidepressant effects, seems to be dependent on its interaction with the dopami...
T6S2227 Spinosin Flavoayamenin Others
1. Spinosin (Flavoayamenin) ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammato...
T21526 α-Guanidinoglutaric Acid Others
α-Guanidinoglutaric Acid is found in cobalt-induced epileptogenic focus tissue in the cerebral cortex of cats. α-Guanidinoglutaric Acid-induced seizures are associated with abnormal serotonergic function and that they ar...
T21629 Loxapine Dopamine Receptor , 5-HT Receptor
Loxapine is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent,used primarily in the treatment of schizophrenia. The drug is a member of the dibenzoxazepine class ...
T76863 Elezanumab AE12-1Y-QL,ABT-555 TGF-beta/Smad
Elezanumab(ABT-555) is a potent human anti-RGMa monoclonal antibody.Elezanumab exerts its inhibitory effect on RGMa-mediated BMP signaling through the SMAD1/5/8 pathway, with an IC50 of approximately 97 pM.Elezanumab pro...
T1483 Citalopram hydrobromide Lu 10-171,Nitalapram HBr,Bonitrile HBr,XU-62-320,Lu 10-171 HBr,Citalopram HBr 5-HT Receptor , Serotonin Transporter , Autophagy
Citalopram hydrobromide (XU-62-320) , a selective serotonin reuptake inhibitor (SSRI), selectively inhibits the CNS neuronal reuptake of serotonin, thereby potentiating serotonergic activity in the central nervous system...
T9169 MPP+ iodide Mitochondrial Metabolism , Autophagy
MPP+ iodide, the metabolite of a neurotoxin MPTP, causes symptom of Parkinson's disease (PD) in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ induces dopamine transporter (DAT) ex...
T23170 PNU-96415E PNU 96415E Others
dopamine D4 and serotonergic 5-HT2A receptor antagonist

Compounds

Mirtazapine
T0137
Synonym: 6-Azamianserin,Org3770
Target: Dopamine Receptor, 5-HT Receptor, Opioid Receptor, Adrenergic Receptor, Histamine Receptor
(Z)-Thiothixene
T13458
Synonym: Thiothixene,Navane,cis-Thiothixene
Target: Serotonin Transporter
4i
T8438
Synonym: CHEMBL1269981,5-HT3 antagonist-4i
Target: 5-HT Receptor
Citalopram
T20828
Synonym: Cipram,Lu 10-171,Lu-10-171 Lu10-171
Target: 5-HT Receptor
Viloxazine
T60325
Synonym: Emovit,Viloxazin
Target: 5-HT Receptor, Norepinephrine
Laprafylline
T68090
Synonym:
Target: Others
Buspirone
T21011
Synonym: Buspirone free base,Ansial
Target: 5-HT Receptor
1-(1-Naphthyl) piperazine hydrochloride
T21569
Synonym: 1-naphthalen-1-ylpiperazine hydrochloride,1-(Naphthalen-1-yl)piperazine hydrochloride
Target: Others
Flibanserin
T4297
Synonym: BIMT-17BS,Girosa,BIMT-17
Target: Dopamine Receptor, 5-HT Receptor
Kaempferitrin
T3386
Synonym: Lespedin,Kaempferol,Lespenephryl,Lespenefril,Kaempferol 3,7-dirhamnoside
Target: cell cycle arrest, Glucokinase, IGF-1R
Vilazodone
T1279
Synonym: SB659746A,EMD 68843
Target: 5-HT Receptor, Serotonin Transporter
Vortioxetine
T2395
Synonym: Lu AA 21004
Target: 5-HT Receptor, Serotonin Transporter
Carvacrol
T4S1990
Synonym: Karvakrol,O-Thymol,cymophenol
Target: Apoptosis, Others, Gamma-secretase, Endogenous Metabolite, Antifungal
Spinosin
T6S2227
Synonym: Flavoayamenin
Target: Others
α-Guanidinoglutaric Acid
T21526
Synonym:
Target: Others
Loxapine
T21629
Synonym:
Target: Dopamine Receptor, 5-HT Receptor
Elezanumab
T76863
Synonym: AE12-1Y-QL,ABT-555
Target: TGF-beta/Smad
Citalopram hydrobromide
T1483
Synonym: Lu 10-171,Nitalapram HBr,Bonitrile HBr,XU-62-320,Lu 10-171 HBr,Citalopram HBr
Target: 5-HT Receptor, Serotonin Transporter, Autophagy
MPP+ iodide
T9169
Synonym:
Target: Mitochondrial Metabolism, Autophagy
PNU-96415E
T23170
Synonym: PNU 96415E
Target: Others
1 2
TargetMol