regulation — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0853	Adenosine	D-Adenosine,Adenine riboside	Apoptosis , Nucleoside Antimetabolite/Analog , Endogenous Metabolite , Autophagy
	Adenosine (D-Adenosine) is a ribonucleoside comprised of adenine bound to ribose, with vasodilatory, antiarrhythmic and analgesic activities.
T2298	ML204		TRP/TRPV Channel
	ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.		TRP/TRPV Channel
T4008	Metergoline	Methergoline,Liserdol	Dopamine Receptor , 5-HT Receptor , Sodium Channel
	Metergoline (Methergoline) is a dopamine agonist and serotonin antagonist. It has been used similarly to BROMOCRIPTINE as a dopamine agonist and also for migraine disorder therapy.		Dopamine Receptor , 5-HT Receptor , Sodium Channel
T2A2481	Taurochenodeoxycholic Acid	Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine	Apoptosis , TNF , Caspase , Endogenous Metabolite
	Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.		Apoptosis , TNF , Caspase , Endogenous Metabolite
TN2215	Taurochenodeoxycholic acid sodium	Sodium taurochenodeoxycholate	Apoptosis , Endogenous Metabolite
	Taurochenodeoxycholic acid sodium (Sodium taurochenodeoxycholate) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and...		Apoptosis , Endogenous Metabolite
TN3910	Ecdysone		Apoptosis , ATPase , Glucocorticoid Receptor , Potassium Channel , Sodium Channel , Endogenous Metabolite , Autophagy
	Ecdysone is a major steroid hormone in insects and herbs. Ecdysone triggers mineralocorticoid receptor activation and induces cellular apoptosis. Ecdysone signaling through Ecdysone receptor isoform B1 is required cell a...
T5014	Prostaglandin E2	PGE2,Dinoprostone,Prostaglandin E2 (PGE2)	Endogenous Metabolite , Prostaglandin Receptor
	Prostaglandin E2 (PGE2) is a naturally occurring hormone involved in a variety of physiological processes in the body, including smooth muscle contraction and relaxation, regulation of vasodilatation and constriction, re...		Endogenous Metabolite , Prostaglandin Receptor
T6S2246	Alisol B 23-acetate	Alisol B Acetate,Alisol B monoacetate,23-O-Acetylalisol B,23-Acetylalismol B	Others
	1. Alisol B 23-acetate (Alisol B Acetate) produces protective effect against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes. 2. Alisol B 23-acetate produces promotiv...		Others
T37078	VEGFR-2-IN-6		VEGFR
	VEGFR-2-IN-6 (WO 02/059110, example 64) is a potent inhibitor of VEGFR2, a crucial receptor involved in the regulation of angiogenesis [1].		VEGFR
TQ0312	Sphingomyelin		Endogenous Metabolite
	Sphingomyelin is a natural sphingolipid that existed in animal cell membranes. It implicates the regulation of transmembrane signaling.		Endogenous Metabolite
T50107	Ethyl 2-[3,5-bis(trifluoromethyl)phenyl]-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate		Others
	ethyl 2-[3,5-bis(trifluoromethyl)phenyl]-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate is a synthetic compound belonging to the curcumin family. It is involved in the regulation of immune response and inflammation through ...		Others
T13881	Dicirenone	SC26304	ATPase , Glucocorticoid Receptor
	Dicirenone (SC26304) inhibits the Mineralocorticoid receptor (MR), aldosterone regulation of the urinary K+:Na+ ratio, and aldosterone binding to renal cytoplasmic and nuclear receptors.		ATPase , Glucocorticoid Receptor
T2795	Amygdalin	Laetrile	Others
	Amygdalin (Laetrile) has antifibrotic, antitumor, anti-inflammatory and analgesic effects, amygdalin joint HSYA could inhibit the degeneration of the endplate chondrocytes derived from intervertebral discs of rats induce...		Others
T8392	L(+)-Asparagine monohydrate		Endogenous Metabolite
	L(+)-Asparagine monohydrate is a non-essential amino acid, participate in neurological and metabolic regulation of tissue cell function.		Endogenous Metabolite
TP1028L	Calcitonin eel acetate	Calcitonin eel acetate (57014-02-5 Free base),Thyrocalcitonin eel	Others
	Calcitonin eel acetate (Calcitonin eel acetate (57014-02-5 Free base)) is the regulation of calcium homeostasis thyroid hormone peptide.		Others
T29170	XU1	Benzo[c][1,8]naphthyridin-6(5h)-One	Aurora Kinase
	XU1（Benzo[c][1,8]naphthyridin-6(5h)-One） is an Aurora protein kinase inhibitor used for the treatment of diseases suitable for inhibition, regulation or modulation of kinase signaling.		Aurora Kinase
T21608L	β-Interleukin I (163-171), human Acetate	β-Interleukin I (163-171), human Acetate(106021-96-9 Free base)	Others
	β-Interleukin I (163-171), human Acetateis a peptide that participate in the regulation of immune responses, inflammatory reactions, and hematopoiesis.		Others
T6S0325	Glycitein	Glycetein	Apoptosis , Others
	1. Gycitein has weak estrogenic activity. 2. Glycitein (Glycetein) inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression.		Apoptosis , Others
T22711	DCB	3,3'-dichlorobenzaldazine	Others , GluR
	DCB (3,3'-dichlorobenzaldazine) is an allosteric ligand for mGluR5 and shows the negative modulatory effect of 3,3′-dimethoxybenzaldazine (DMeOB). DCB blocks the positive allosteric regulation of mGluRs with the help of ...		Others , GluR
T29857	Alethine	β-Alethine	TNF
	Alethine (β-Alethine) is a small molecule compound with antitumour activity and is used to treat tumours and infections. The alethine-induced up-regulation of TNFα increases the cytotoxicity of T cells.		TNF