psychiatric — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3158	Harmane	Loturine,Harman,Aribine	Adrenergic Receptor , Monoamine Oxidase , Imidazoline Receptor
	Harmane (Loturine) is a bio-active β-Carboline and monoamine oxidase inhibitor found in coffee and tobacco smoke.
T22016	A-582941 dihydrochloride	A 582941	5-HT Receptor , AChR
	A-582941 dihydrochloride (A 582941) is a Selective agonist of α7 nAChR partial		5-HT Receptor , AChR
T7706	LY-404187		GluR , iGluR
	LY404187 is a positive allosteric modulator of AMPA receptors		GluR , iGluR
T28368	PF-04859989 HCl	PF 04859989,PF04859989,PF-04859989HCl,PF-04859989	Others
	PF-04859989 HCl is a brain-penetrable irreversible inhibitor of kynurenine amino transferase II (KAT II), the enzyme responsible for most of the brain synthesis of kynurenic acid. PF-04859989 HCl has been implicated in s...		Others
T0024	Primidone	Primaclone,Mysoline,NCI-C56360	GABA Receptor , Sodium Channel , GluR , AChR
	Primidone (NCI-C56360) is a potent anticonvulsant agent. It is a neuronal voltage-gated sodium channel blocker and has value in the study of epilepsy, essential tremor, and psychiatric disorders.		GABA Receptor , Sodium Channel , GluR , AChR
T24656	PQ-10	A844337,PQ 10,A-844337,A 844337	PDE
	PQ-10 (A-844337) is a PDE-10 inhibitor. PQ-10 induces brain glucose metabolism patterns, which may be a potential translational biomarker.		PDE
T7165	Basmisanil	RG1662,RO5186582	GABA Receptor
	Basmisanil (RG1662) is a negative allosteric modulator/inverse agonist of GABAAα5 receptors.Formulations containing basmisanil are in clinical trials for the treatment of cognitive impairments associated with Down syndro...		GABA Receptor
T0678	Amitriptyline hydrochloride	Amitriptyline HCl,Tryptizol,Domical,Annoyltin	Trk receptor , Sigma receptor , 5-HT Receptor , Serotonin Transporter , Sodium Channel , Adrenergic Receptor , AChR , Norepinephrine , Histamine Receptor
	Amitriptyline hydrochloride (Annoyltin) is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive activities.
T20324	Butyrophenone	NSC8463,NSC 8463,NSC-8463	Others
	Butyrophenone (NSC-8463) is a chemical compound. Some of its derivatives are used to treat various psychiatric disorders.		Others
T5444	CLP290	CLP-290	Potassium Channel
	CLP290 is an activator of the neuron-specific K+-Cl cotransporter KCC2 and displays potential for the treatment of a wide range of neurological and psychiatric indications.		Potassium Channel
T50061	[4-(4-phenylpiperazin-1-yl)oxan-4-yl]methanamine		Others
	[4-(4-phenylpiperazin-1-yl)oxan-4-yl]methanamine is a piperazine derivative that is a partial agonist at serotonin and dopamine receptors, making it a candidate for the treatment of psychiatric disorders such as depressi...		Others
T50054	Opromazine hydrochloride		Others
	Opromazine hydrochloride belongs to the phenothiazine class of antipsychotics and reduces the activity of dopaminergic pathways by blocking dopamine receptors in the brain. It is mainly used for the treatment of psychiat...		Others
T31079	CP-810123	CP 810123,UNII-E6G4550EC4,CP810123	AChR
	CP-810123 is a new alpha 7 nAChR agonist for the treatment of cognitive impairment associated with psychiatric or neurological disorders such as schizophrenia and Alzheimer's disease.		AChR
T83974	OPC18750 HCl		PDE
	OPC18750 HCl is a potential phosphodiesterase inhibitor with positive inotropic effects that can be used to study asthma, cancer, diabetes, and psychiatric disorders.		PDE
T23066	NGD 94-1		Dopamine Receptor
	NGD 94-1 is a selective D4 receptor antagonist with an affinity of 3 nM for the D4 receptor and greater than 2 pM for the D1, D2, D3, and D5 receptors.NGD 94-1 can be used in the study of cognitive disorders and other ps...		Dopamine Receptor
T1292	Tiapride hydrochloride		Dopamine Receptor
	Tiapride is a selective blocker of D2/3 dopamine receptors in the brain. It is used in the therapy of various psychiatric and neurological disorders containing dyskinesia, negative symptoms of psychosis, alcohol withdraw...		Dopamine Receptor
T77597	SXC 2023	(S)-2-acetamido-3-(4-methylbenzoylthio)propanoic acid	Others
	SXC 2023 ((S)-2-acetamido-3-(4-methylbenzoylthio)propanoic acid) is a therapeutic prodrug of N-acetyl-L-cysteine for the treatment of CNS disorders and neurocognitive disorders, and can be used to treat glutamatergic dys...		Others
T50111	6-Fluorotryptamine hydrochloride		Others
	6-Fluorotryptamine hydrochloride is a compound used as a molecular structural unit and is a derivative of the natural tryptamine alkaloid serotonin. It is an agonist at 5-HT2A and 5-HT2C serotonin receptors, making it a ...		Others
T67811	Tefludazine
	Tefludazine, a novel neuroleptic with a benzindone structure, is a compound with good oral activity and antagonistic effects on dopamine and 5-hydroxytryptamine receptors. Tefludazine has shown potent dopamine (DA) antag...
T0256	Citric acid trilithium salt tetrahydrate	Lithium citrate tribasic tetrahydrate,Trilithium citrate tetrahydrate	Dehydrogenase , GSK-3 , HIF/HIF Prolyl-Hydroxylase , Antibacterial , GluR
	Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) , the active component of Lithium, is a medicine used in the therapy of psychiatric disease. It has shown the effects of signaling pathways...