protective — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8158	Tilianin		Others
	Tilianin is a flavonoid glycoside of Dragocephalum moldavicum L.		Others
T5336	Zacopride hydrochloride		Potassium Channel , 5-HT Receptor
	Zacopride is a highly potent 5-HT3 receptor antagonist (Kd = 0.38 nM) and 5-HT4 receptor agonist (Ki = 373 nM). It also is a selective IK1 channel agonist.		Potassium Channel , 5-HT Receptor
T2519	Lercanidipine	Masnidipine	Calcium Channel
	Lercanidipine (Masnidipine) is a calcium channel blocker of the dihydropyridine class.		Calcium Channel
T16695	Pyrintegrin		Integrin
	Pyrintegrin is an β1-integrin agonist that promotes embryonic stem cells' survival. Pyrintegrin can be used as a podocyte-protective agent. Pyrintegrin enhances cell-extracellular matrix adhesion-mediated integrin signal...		Integrin
T2808	Bilobalide	(-)-Bilobalide	Apoptosis , Endogenous Metabolite , Autophagy
	Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.		Apoptosis , Endogenous Metabolite , Autophagy
T0412	Idebenone	CV-2619	Apoptosis , Antioxidant , Mitochondrial Metabolism
	Idebenone (CV-2619) is a synthetic analogue of ubiquinone (Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC).		Apoptosis , Antioxidant , Mitochondrial Metabolism
T0081	Lafutidine	FRG-8813	5-HT Receptor , Histamine Receptor
	Lafutidine (FRG-8813) is a newly developed histamine H(2)-receptor antagonist, which can inhibit gastric acid secretion.		5-HT Receptor , Histamine Receptor
T6S1525	3,4-Dicaffeoylquinic acid	Isochlorogenic acid B	Apoptosis , Antioxidant , Influenza Virus , Endogenous Metabolite
	3,4-Dicaffeoylquinic acid (Isochlorogenic acid B) has antioxidant activity.
T16812	RWJ-67657	JNJ 3026582	p38 MAPK
	RWJ-67657 (JNJ 3026582) is an orally active and selective p38α and p38β MAPK inhibitor (IC50s: 1 and 11 μM, respectively). RWJ-67657 shows no activity at p38γ and p38δ and shows a cardioprotective effect.		p38 MAPK
T2S1200	Sinapine		Antioxidant , P-gp , AChE
	1. Sinapine, an alkaloid from seeds of the cruciferous species, can be used as an effective natural compound for chemo-resistance. 2. Sinapine has antioxidant and radio-protective activities.		Antioxidant , P-gp , AChE
T6874	Lercanidipine hydrochloride	Corifeo,Carmen,Cardiovasc	Calcium Channel
	Lercanidipine hydrochloride (Corifeo) is a calcium channel blocker of the dihydropyridine class.		Calcium Channel
T3392	Sinapine thiocyanate		P-gp , AChE
	Sinapine Thiocyanate, is a derivative of Sinapine (S486605), an alkaloidal amine found in black mustard seeds. It is the choline ester of Sinapic Acid (S486800). It is also a phenolic-chloine conjugates, acting as anti-o...		P-gp , AChE
T6374	Alfacalcidol	Bondiol,Etalpha,1-hydroxy Vitamin D3,1.alpha.-Hydroxyvitamin D3,1-hydroxycholecalciferol	Others
	Alfacalcidol (Etalpha) (1-hydroxycholecalciferol; Alpha D3; 1.alpha.-Hydroxyvitamin D3) is a non-selective VDR activator medication.		Others
TN6774	Emodin 6-O-β-D-glucoside	Glucoemodin	Others
	Emodin 6-O-β-D-glucoside (Glucoemodin) can protect barrier integrity and inhibit HMGB1-mediated inflammatory responses, which suggests a potential use as a therapy for sepsis or septic shock. Emodin 6-O-beta-D-glucoside ...		Others
T6S1917	Schisandrol B	Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B	P450 , Reactive Oxygen Species , Autophagy
	1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Schisandrol B has a...		P450 , Reactive Oxygen Species , Autophagy
T5145	Oxytocin acetate	Oxytocic hormone acetate,α-Hypophamine acetate,Oxytocin acetate (50-56-6 free base)	Oxytocin Receptor
	Oxytocin acetate (α-Hypophamine acetate) is a mammalian neurohypophysial hormone, a ligand of oxytocin receptor.		Oxytocin Receptor
T80778	Weak Hepatoprotective agent-1
	Compound 11, labeled as a weak Hepatoprotective agent-1, is a naturally occurring substance extracted from the fruits of Arctium lappa L. It demonstrates modest hepatoprotective effects when applied at a concentration of...
T24840	STS-E412	STSE412
	STS-E412 is a selective activator of the tissue-protective EPOR/CD131 receptor.
TQ0226	Jionoside B1		Others
	Jionoside B1 has immunosuppressive activity and shows the hepato-protective activity in the H2O2 induced liver injury experiments.		Others
T3S1534	Secoxyloganin		Anti-infection
	Secoxyloganin possesses a hepato-protective effect. Secoxyloganin possesses antibacterial activity. Secoxyloganin has cytotoxic activity against UACC-62 cell line.Secoxyloganin possesses the perfect protective effect on ...		Anti-infection