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STS-E412

Catalog No. T24840 CAS 1609980-39-3

Synonyms: STS E412, STSE412

STS-E412 is a tissue-protective and selective EPOR/CD131 receptor activator for the study of neurological disorders.

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STS-E412, CAS 1609980-39-3

Pack Size	Availability	Price/USD
1 mg	In stock	$ 58.00
2 mg	In stock	$ 83.00
5 mg	In stock	$ 139.00
10 mg	In stock	$ 222.00
25 mg	In stock	$ 396.00
50 mg	In stock	$ 653.00
1 mL * 10 mM (in DMSO)	In stock	$ 153.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

STS-E412 is a tissue-protective and selective EPOR/CD131 receptor activator for the study of neurological disorders.

Synonyms	STS E412, STSE412
Molecular Weight	318.76
Formula	C15H15ClN4O2
CAS No.	1609980-39-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 30 mg/mL (94.11 mM), Sonification is recommended.

References and Literature

1. Miller JL, et al. Discovery and Characterization of Nonpeptidyl Agonists of the Tissue-Protective Erythropoietin Receptor. Mol Pharmacol. 2015 Aug;88(2):357-67. 2. Miller JL, Rai M, Frigon NL, Pandolfo M, Punnonen J, Spencer JR. Erythropoietin and small molecule agonists of the tissue-protective erythropoietin receptor increase FXN expression in neuronal cells in vitro and in Fxn-deficient KIKO mice in vivo. Neuropharmacology. 2017 Sep 1;123:34-45. doi: 10.1016/j.neuropharm.2017.05.011. Epub 2017 May 11.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

STS-E412 1609980-39-3 Others STS-E-412 STS E412 STSE412 STSE 412 STS-E 412 STSE-412 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.