programmed — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4004	Concanavalin A		Apoptosis
	Concanavalin A is a plant lectin that is a T cell mitogen. It induces apoptosis in human fibroblasts.		Apoptosis
T9066	Merafloxacin	CI 934	SARS-CoV
	Merafloxacin (CI 934) is a fluoroquinolone antibacterial, which was also identified as a 1 PRF inhibitor of SARS-CoV-2.		SARS-CoV
T12379	PD-1-IN-22		Others , PD-1/PD-L1
	PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor(IC50 of 92.3 nM).		Others , PD-1/PD-L1
T3146	BMS-202	PD1-PDL1 inhibitor 2,PD-1/PD-L1 inhibitor 2	Apoptosis , PD-1/PD-L1
	BMS-202 (PD1-PDL1 inhibitor 2) is an inhibitor of the PD-1 (Programmed death- 1) /PD-Ll (Programmed death-ligand 1) protein/protein interaction.		Apoptosis , PD-1/PD-L1
T67568	Fmoc-Met-OH	Fmoc-L-Met-OH
	Fmoc-Met-OH (Fmoc-L-Met-OH) is an fmoc-based programmed synthesis of methionine derivatives.
T11484	GSK2593074A	GSK'074	TNF , RIP kinase
	GSK2593074A (GSK'074) is a programmed necrosis inhibitor that displays inhibitory effects on RIP1 and RIP3.		TNF , RIP kinase
T3890	Verbenalin	Verbenalol β-D-glucopyranoside,Verbenaloside,Verbenalol glucoside,Cornin	Others
	Verbenalin (Verbenaloside) induces angiogenesis via a programmed PI3K/Akt/eNOS/VEGF signaling axis.		Others
T21936	M50054		Caspase
	Apoptosis Inhibitor was a novel inhibitor of programmed cell death associate with caspase-3 inhibition.		Caspase
T9907	Nivolumab		PD-1/PD-L1
	Nivolumab (anti-PD-1) is a genetically engineered fully human immunoglobulin Ig) G4 monoclonal antibody directed against the negative immunoregulatory human cell surface receptor programmed death-1PD-1PCD-1) with immune ...		PD-1/PD-L1
T77346	2-aminobenzo[d]thiazol-6-ol
	2-aminobenzo[d]thiazol-6-ol has antimicrobial, antioxidant and anticancer properties and may inhibit the activity of certain cancer cell lines by inducing apoptosis or programmed cell death.
T50016	2-amino-4-methyl-1,3-thiazole-5-carbohydrazide		Others
	2-amino-4-methyl-1,3-thiazole-5-carbohydrazide (AMTCH) has antitumor activity and inhibits the growth of cancer cells by inducing apoptosis or programmed cell death. It also has antibacterial and fungal activity.		Others
T83970	IMMH 010 maleate	YPD-30 maleate	PD-1/PD-L1
	IMMH 010 maleate (YPD-30 maleate) is an orally available programmed cell death ligand 1 inhibitor with potential antitumor activity for the study of neurological disorders and advanced malignant solid tumors.		PD-1/PD-L1
T72253	AXC-715 trihydrochloride	T785 trihydrochloride	TLR
	AXC-715 trihydrochloride (T785 trihydrochloride) is a TLR7/TLR8 dual agonist for the synthesis of antibody-adjuvanted immunocouplings. The couplings are mostly programmed death ligand 1 (PD-L1) attached to one or more an...		TLR
T4558	Trioxsalen	Trimethylpsoralen,Trioxysalen,Trisoralen	DNA Alkylator/Crosslinker , DHFR
	Trioxsalen (Trioxysalen) is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy treatment of vitiligo and hand eczema. After photoactivation it creates interstrand cross-links in DNA, wh...		DNA Alkylator/Crosslinker , DHFR
T76750	Cemiplimab	REGN-2810,SAR-439684	Others
	Cemiplimab (Anti-Human PD-1) is a human monoclonal antibody against programmed cell death receptor 1 (PD-1) and a checkpoint inhibitor that blocks PD-1/PD-L1 mediated T-cell inhibition and can be used in metastatic cance...		Others
T40111L	BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride		PD-1/PD-L1
	BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride is a resorcinol di-Ph ether scaffold-based programmed cell death-1 (PD-1)/programmed cell death ligand 1 (PD-L1) inhibitor that inhibits the PD-1/PD-L1 interaction wi...		PD-1/PD-L1
T3655	BMS-1	PD1-PDL1 inhibitor 1,PD-1/PD-L1 inhibitor 1	Apoptosis , PD-1/PD-L1
	BMS-1 (PD-1/PD-L1 inhibitor 1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts as an immunomodulator. Programmed death ligand 1 (PD-L1) is a protein in humans that is encoded by the CD274 gene ...		Apoptosis , PD-1/PD-L1
T3895	Polyphyllin I		Apoptosis , Akt , JNK , PDK , mTOR , Autophagy
	Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D ha...		Apoptosis , Akt , JNK , PDK , mTOR , Autophagy
T4881	Phosphorylethanolamine	O-Phosphorylethanolamine	Others , Endogenous Metabolite
	Phosphorylethanolamine (O-Phosphorylethanolamine) is a phosphomonoester metabolite of the phospholipid metabolism. Phosphorylethanolamine is a precursor of phospholipid synthesis and a product of phospholipid breakdown. ...		Others , Endogenous Metabolite
T12378L	CA-170	PD-1-IN-1	Others
	PD-1-IN-1 is a programmed cell dealth-1inhibitor. PD-1-IN-1 can be used as an immune modulator.		Others