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Trioxsalen

Catalog No. T4558   CAS 3902-71-4
Synonyms: Trimethylpsoralen, Trioxysalen, Trisoralen

Trioxsalen (Trioxysalen) is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy treatment of vitiligo and hand eczema. After photoactivation it creates interstrand cross-links in DNA, which can cause programmed cell death.

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Trioxsalen Chemical Structure
Trioxsalen, CAS 3902-71-4
Pack Size Availability Price/USD Quantity
25 mg In stock $ 29.00
1 mL * 10 mM (in DMSO) In stock $ 48.00
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Purity: 98.96%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Trioxsalen (Trioxysalen) is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy treatment of vitiligo and hand eczema. After photoactivation it creates interstrand cross-links in DNA, which can cause programmed cell death.
Synonyms Trimethylpsoralen, Trioxysalen, Trisoralen
Molecular Weight 228.24
Formula C14H12O3
CAS No. 3902-71-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 2.28 mg/mL (10 mM), Sonication is recommended.

TargetMolReferences and Literature

1. Hadjipavlou-Litina D,etal.Trioxsalen derivatives with lipoxygenase inhibitory activity.J Enzyme Inhib Med Chem. 2009 Dec;24(6):1351-6.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Drug Library Microbial Natural Product Library Anti-Cancer Approved Drug Library Tyrosine Kinase Inhibitor Library Traditional Chinese Medicine Monomer Library Drug Repurposing Compound Library Bioactive Compounds Library Max Approved Drug Library FDA-Approved Drug Library Anti-Tumor Natural Product Library

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Related compounds with same targets
Chlorambucil N-Nitroso-N-methylurea Procarbazine hydrochloride RITA Pipobroman Cyclophosphamide hydrate Oxaliplatin Streptozocin

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Keywords

Trioxsalen 3902-71-4 Cell Cycle/Checkpoint DNA Damage/DNA Repair Metabolism DHFR DNA Alkylator/Crosslinker Trimethylpsoralen vitiligo hyperproliferative TMP Trioxysalen Inhibitor skin anti-inflammatory diseases eczema hand Trisoralen inhibit inhibitor

 

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