peroxidase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T19508	Peroxidase		Others
	Peroxidase, found in the roots of horseradish, actively involves in oxidizing reactive oxygen species, innate immunity, hormone biosynthesis, and pathogenesis of several diseases.		Others
T80056	Glutathione Peroxidase	GSH-Px,EC 1.11.1.9	Glutathione Peroxidase
	Glutathione Peroxidase (GSH-Px; EC 1.11.1.9), a member of the peroxidase family, catalyzes the oxidation of reduced glutathione (GSH) to oxidized glutathione (GSSG) by forming a disulfide bridge, concurrently reducing hy...		Glutathione Peroxidase
T83780	GPX4 24	Phospholipid Hydroperoxide Glutathione Peroxidase 24,PHGPx 24,Glutathione Peroxidase 4 24
	GPX4 24, a derivative of (1S,3R)-RSL3, acts as a potent inhibitor of glutathione peroxidase 4 (GPX4) through covalent binding in a concentration-dependent manner within 4T1 murine mammary carcinoma cells. This compound e...
T37314	JKE-1674		GPX
	JKE-1674 is an inhibitor of glutathione peroxidase 4 (GPX4). JKE-1674 is an active metabolite of the GPX4 inhibitor ML-210.		GPX
T8375	ML-210	CID 49766530	Ferroptosis , GPX , Glutathione Peroxidase , Ras
	ML-210 (CID 49766530) is a selective RAS and covalent glutathione peroxidase 4 (GPX4) inhibitor(GPX4, EC50 : 30 nM), with anti-cancer activity		Ferroptosis , GPX , Glutathione Peroxidase , Ras
T5340	MPO-IN-28		Glutathione Peroxidase
	MPO-IN-28 is a novel potent, irreversible Myeloperoxidase (MPO) inhibitor with IC50 of 44 nM.		Glutathione Peroxidase
T4090	PF-06282999		Glutathione Peroxidase
	PF-06282999 is a potent and selective myeloperoxidase inhibitor which is potentially useful for the treatment of cardiovascular diseases.		Glutathione Peroxidase
T14379	AZD5904		Glutathione Peroxidase
	AZD5904 is a potent and irreversible human Myeloperoxidase (MPO) inhibitor(IC50 of 140 nM and has similar potency in mouse and rat).		Glutathione Peroxidase
T12189	NBDHEX		Apoptosis , Glutathione Peroxidase , Autophagy
	NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1) .		Apoptosis , Glutathione Peroxidase , Autophagy
T8970	ML162		Ferroptosis , GPX , Glutathione Peroxidase
	ML162 is an inhibitor of GPX4 that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50s = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively)		Ferroptosis , GPX , Glutathione Peroxidase
T5463	Verdiperstat	AZD3241,AZD 3241	Glutathione Peroxidase
	Verdiperstat (AZD 3241) is a selective, irreversible and orally active myeloperoxidase inhibitor, with an IC50 of 630 nM, and can be used in the research of neurodegenerative brain disorders.		Glutathione Peroxidase
T5372	L-SelenoMethionine	L-(+)-Selenomethionine	Apoptosis , Amino Acids and Derivatives , Endogenous Metabolite
	L-SelenoMethionine (L-(+)-Selenomethionine) is a naturally occurring amino acid. It promotes cell cycle progression and elevates the expression of the antioxidant enzymes thioredoxin reductase, glutathione reductase.
T3646	RSL3	RSL3 1S,1S,3R-RSL3	Ferroptosis , GPX , Glutathione Peroxidase
	RSL3 (RSL3 1S) is an inhibitor of GPX4, and inhibits system xc- that blocks GSH synthesis (IC50=100 nM). RSL3 is a VDAC-independent activator of iron death that is selective for tumor cells carrying oncogenic RAS.		Ferroptosis , GPX , Glutathione Peroxidase
T4313	Tinoridine hydrochloride	Nonflamin,Y-3642 hydrochloride	COX , Glutathione Peroxidase
	Tinoridine hydrochloride (Y-3642 hydrochloride) is a non-steroidal anti-inflammatory drug. Tinoridine hydrochloride (5-100 μM), produced a concentration-dependent inhibition on the simultaneous increases in lipid peroxid...		COX , Glutathione Peroxidase
TJS0338	4-Methylesculetin	4-Methyl-6,7-dihydroxycoumarin,Methylesculetin	Antioxidant , Glutathione Peroxidase
	4-Methylesculetin (Methylesculetin) is one of the coumarin derivatives with great anti-oxidant and anti-inflammatory activities.		Antioxidant , Glutathione Peroxidase
T26389	4-POBN	NSC-640,NSC640,4-Aminobenzohydrazide,NSC 640,Myeloperoxidase Inhibitor 1,4-ABAH	Glutathione Peroxidase
	4-POBN (Myeloperoxidase Inhibitor 1) is a potent and irreversible inhibitor of myeloperoxidase (IC50 = 0.3 µM). 4-POBN can be used in studies about subacute stroke.		Glutathione Peroxidase
T0825	Ebselen	SPI-1005,PZ-51,CCG-39161	Phosphatase , Virus Protease , Calcium Channel , COX , HIV Protease
	Ebselen (CCG-39161) is a organoselenium compound with anti-inflammatory, anti-oxidant and cytoprotective activity. Ebselen acts as a glutathione peroxidase mimetic and is thereby able to prevent cellular damage induced b...
T1374	2-Pyridinecarbohydrazide	2-Picolinyl hydrazide	Dehydrogenase , CAT
	2-Pyridinecarbohydrazide (2-Picolinyl hydrazide) is an effective inhibitor of Catalase-peroxidase-NAPDH.		Dehydrogenase , CAT
T18908	ABTS diammonium salt	AzBTS-(NH4)2	Others
	ABTS diammonium salt (AzBTS-(NH4)2) is used as a substrate for horseradish peroxidase (HRP) conjugate.		Others
T18912	ADHP	10-Acetyl-3,7-dihydroxyphenoxazine	Others
	ADHP (10-Acetyl-3,7-dihydroxyphenoxazine) is a fluorogenic peroxidase substrate (λex=530 nm, λem=590 nm).		Others