Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ML162 is an inhibitor of GPX4 that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50s = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively)
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 91.00 | |
10 mg | In stock | $ 141.00 | |
25 mg | In stock | $ 297.00 | |
50 mg | In stock | $ 482.00 | |
100 mg | In stock | $ 591.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 98.00 |
Description | ML162 is an inhibitor of GPX4 that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50s = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively) |
Molecular Weight | 477.4 |
Formula | C23H22Cl2N2O3S |
CAS No. | 1035072-16-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 4.77 mg/mL (10 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
ML162 1035072-16-2 Apoptosis Metabolism oxidation-reduction Ferroptosis GPX Glutathione Peroxidase p62 GPX4 Nrf2 anticancer ML 162 HRAS ML-162 Inhibitor inhibit inhibitor