Powder: -20°C for 3 years
In solvent: -80°C for 2 years
ML162 is an inhibitor of GPX4 that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50s = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively)
Description | ML162 is an inhibitor of GPX4 that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50s = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively) |
Molecular Weight | 477.4 |
Formula | C23H22Cl2N2O3S |
CAS No. | 1035072-16-2 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 10 mM
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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ML162 1035072-16-2 代谢 凋亡 细胞周期 氧化还原 Ferroptosis Glutathione Peroxidase GPX p62 GPX4 ML-162 Nrf2 anticancer HRAS Inhibitor inhibit ML 162 inhibitor