Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Tinoridine hydrochloride (Y-3642 hydrochloride) is a non-steroidal anti-inflammatory drug. Tinoridine hydrochloride (5-100 μM), produced a concentration-dependent inhibition on the simultaneous increases in lipid peroxide formation and renin release induced by 50 μM ascorbic acid in the renin granule fraction. On the other hand, indomethacin, hydrocortisone, and prednisolone, which had no ability to inhibit the lipid peroxidation in the renin granule fraction, did not influence the release of renin from the granules. These results suggest that tinoridine suppresses renin release by inhibiting the oxidative disintegration of membranes of renin granules.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 34.00 | |
2 mg | In stock | $ 48.00 | |
5 mg | In stock | $ 80.00 | |
10 mg | In stock | $ 128.00 | |
25 mg | In stock | $ 237.00 | |
50 mg | In stock | $ 383.00 | |
100 mg | In stock | $ 555.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 89.00 |
Description | Tinoridine hydrochloride (Y-3642 hydrochloride) is a non-steroidal anti-inflammatory drug. Tinoridine hydrochloride (5-100 μM), produced a concentration-dependent inhibition on the simultaneous increases in lipid peroxide formation and renin release induced by 50 μM ascorbic acid in the renin granule fraction. On the other hand, indomethacin, hydrocortisone, and prednisolone, which had no ability to inhibit the lipid peroxidation in the renin granule fraction, did not influence the release of renin from the granules. These results suggest that tinoridine suppresses renin release by inhibiting the oxidative disintegration of membranes of renin granules. |
Synonyms | Nonflamin, Y-3642 hydrochloride |
Molecular Weight | 352.88 |
Formula | C17H21ClN2O2S |
CAS No. | 25913-34-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 12.5 mg/mL (35.42 mM)
You can also refer to dose conversion for different animals. More
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Tinoridine hydrochloride 25913-34-2 Immunology/Inflammation Metabolism Neuroscience Glutathione Peroxidase COX Tinoridine Y-3642 Hydrochloride Inhibitor inhibit Y3642 Y3642 Hydrochloride Y 3642 Tinoridine Hydrochloride Nonflamin Y-3642 Y 3642 Hydrochloride Y-3642 hydrochloride inhibitor