store at low temperature,store under nitrogen,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ADHP (10-Acetyl-3,7-dihydroxyphenoxazine) is a fluorogenic peroxidase substrate (λex=530 nm, λem=590 nm).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 35.00 | |
5 mg | In stock | $ 98.00 | |
10 mg | In stock | $ 148.00 | |
25 mg | In stock | $ 248.00 | |
50 mg | In stock | $ 372.00 | |
100 mg | In stock | $ 546.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 91.00 |
Description | ADHP (10-Acetyl-3,7-dihydroxyphenoxazine) is a fluorogenic peroxidase substrate (λex=530 nm, λem=590 nm). |
In vitro | To obtain the parameters Km and kcat for Compound I, two independent methods are used. Initially, the oxidation of ADHP using the injector functionality built-in to the fluorescence plate reader is studied. The auto-injector dispenses the H2O2 to initiate the reaction, as a means of generating a set of progress curves. Analysis for MPO-mediated oxidation of ADHP gives a Km of 31±4 μM and the kcat of 186± 6/s. The kobs also increase over the experimental range of ADHP concentrations from 1 to 80 μM and for the converse experiment holding substrate constant over 3 to 45 nM MPO. The apparent second-order rate constant obtain from the slope of kobs against ADHP concentration Kappon is 2.1±0.2 mM/s. |
Synonyms | 10-Acetyl-3,7-dihydroxyphenoxazine |
Molecular Weight | 257.24 |
Formula | C14H11NO4 |
CAS No. | 119171-73-2 |
store at low temperature,store under nitrogen,keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/ml (233.25 mM)
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ADHP 119171-73-2 Others 10-Acetyl-3,7-dihydroxyphenoxazine inhibit Inhibitor inhibitor