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Search Results for " nephropathy "

20

Compounds

Cat No. Product Name Synonyms Targets
T16695 Pyrintegrin Integrin
Pyrintegrin is an β1-integrin agonist that promotes embryonic stem cells' survival. Pyrintegrin can be used as a podocyte-protective agent. Pyrintegrin enhances cell-extracellular matrix adhesion-mediated integrin signal...
TN1644 Flavanomarein Others
Flavanomarein demonstrates potent antioxidative property, including free radical scavenging activity, inhibition of lipid peroxidation, as well as lipid-lowering effects in human HepG2 hepatocellular carcinoma cells trea...
T16724 Razuprotafib AKB-9778 Phosphatase , Others
Razuprotafib (AKB-9778) is a protein tyrosine phosphatase ß (HPTPß) inhibitor (IC50: 50 nM). Razuprotafib is effective for the activation of Tie-2 and is protective against acute kidney injury.
T14002 12-Ketodeoxycholic acid Endogenous Metabolite
12-Ketodeoxycholic acid, a bile acid and kidney metabolite, serves as a detectable marker for kidney injury [1].
T0476 Spironolactone SC9420,Abbolactone Glucocorticoid Receptor , Androgen Receptor , Autophagy
Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.
T8408 GKT136901 AK120765 NADPH-oxidase , NADPH
GKT136901 (AK120765) is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite
T6542 Imidapril hydrochloride Novaloc,Imidapril HCl,Tanapril,TA-6366 RAAS
Imidapril hydrochloride (Tanapril) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension.
TN1471 Cassiaside C Toralactone 9-O-β-D-gentiobioside Others , Endogenous Metabolite
Cassiaside C (Toralactone 9-O-β-D-gentiobioside), a naphthopyrone extracted from Cassia tora seeds, exhibits in vitro inhibitory activity against the formation of advanced glycation end products (AGE).
T28360 PF-00489791 PF-4634817,PF 4634817,PF00489791,PF 00489791,PF4634817 PDE
PF-00489791 (PF4634817) is a long-acting PDE5 inhibitor with hypotensive activity for the study of diabetic nephropathy.
T6486 Enalapril Maleate MK-421 Maleate,Renitec Maleate,Glioten Maleate,MK-421 (maleate),Vasotec Maleate RAAS
Enalapril Maleate (MK-421 Maleate), an angiotensin-converting enzyme (ACE) inhibitor, is utilized in the treatment of hypertension, chronic heart failure , and diabetic nephropathy.
TP1761L Handle region peptide, rat acetate Handle region peptide, rat acetate(749227-53-0 free base) Others
Handle region peptide, rat acetate is a prorenin receptor antagonist, suppresses the progression of diabetic nephropathy and has anti-inflammatory in the eye.
T24626 PF-249 PF-06685249,PF 06685249,PF06685249 AMPK
PF-249 (PF-06685249) is a β1-selective AMPK with an EC50 of 12 nM for AMPK α1β1γ1 and can be used in studies about diabetic nephropathy.
T0358 Aminoguanidine hydrochloride Imino semicarbazide,Pimagedine hydrochloride,CP-12009-18 tartrate,Hydrazinecarboximidamide,Guanyl hydrazine,Pimagedine NOS , NO Synthase
Aminoguanidine hydrochloride (Hydrazinecarboximidamide) is a diamine oxidase and NO synthase inhibitor, used in the treatment of diabetic nephropathy.
TP1978L NFAT inhibitor, Cell Permeable aceate Others
NFAT inhibitor, Cell Permeable aceate is a cell-permeable nuclear factor of activated T cells (NFAT) inhibitor. It can be used for the research of podocyte and diabetic nephropathy.
T6S1367 Procyanidin B2 Proanthocyanidin B2 Reactive Oxygen Species , NOD
Procyanidin B2 (Proanthocyanidin B2) has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inflammasome activation via suppression ...
T0778 Phenacetin Acetophenetidin COX
Phenacetin (Acetophenetidin) is a phenylacetamide that was formerly used in ANALGESICS but nephropathy and METHEMOGLOBINEMIA led to its withdrawal from the market.
T14301 Apararenone MT-3995 Glucocorticoid Receptor
Apararenone (MT-3995) is a receptor antagonist of mineralocorticoid receptor which can be used to treat non-alcoholic steatohepatitis and diabetic nephropathy.
TL0001 Dencichine L-Dencichin,ODAP,Dencichin Others , HIF/HIF Prolyl-Hydroxylase
Dencichine (ODAP) is a neurotoxic agent. Dencichine is a haemostatic agent, the hemostatic effect relates to modulation of the coagulation system, platelet aggregation and fibrinolytic system. It has renoprotective effec...
T24270 KS370G KS-370-G,KS 370 G,Caffeic Acid Phenethyl Amide
KS370G (Caffeic Acid Phenethyl Amide) inhibits UUO-induced renal fibrosis marker expression. KS370G is an orally active hypoglycemic and cardioprotective agent that reduces collagen deposition in obstructed kidneys and s...
T35689 MTP 131 acetate Others
MTP 131 is a mitochondria-targeted peptide antioxidant.1,2It localizes to the mitochondria and reducestert-butyl hydroperoxide-induced lipid peroxidation and apoptosis in SH-SY5Y cells when used at concentrations ranging...

Compounds

Pyrintegrin
T16695
Synonym:
Target: Integrin
Flavanomarein
TN1644
Synonym:
Target: Others
Razuprotafib
T16724
Synonym: AKB-9778
Target: Phosphatase, Others
12-Ketodeoxycholic acid
T14002
Synonym:
Target: Endogenous Metabolite
Spironolactone
T0476
Synonym: SC9420,Abbolactone
Target: Glucocorticoid Receptor, Androgen Receptor, Autophagy
GKT136901
T8408
Synonym: AK120765
Target: NADPH-oxidase, NADPH
Imidapril hydrochloride
T6542
Synonym: Novaloc,Imidapril HCl,Tanapril,TA-6366
Target: RAAS
Cassiaside C
TN1471
Synonym: Toralactone 9-O-β-D-gentiobioside
Target: Others, Endogenous Metabolite
PF-00489791
T28360
Synonym: PF-4634817,PF 4634817,PF00489791,PF 00489791,PF4634817
Target: PDE
Enalapril Maleate
T6486
Synonym: MK-421 Maleate,Renitec Maleate,Glioten Maleate,MK-421 (maleate),Vasotec Maleate
Target: RAAS
Handle region peptide, rat acetate
TP1761L
Synonym: Handle region peptide, rat acetate(749227-53-0 free base)
Target: Others
PF-249
T24626
Synonym: PF-06685249,PF 06685249,PF06685249
Target: AMPK
Aminoguanidine hydrochloride
T0358
Synonym: Imino semicarbazide,Pimagedine hydrochloride,CP-12009-18 tartrate,Hydrazinecarboximidamide,Guanyl hydrazine,Pimagedine
Target: NOS, NO Synthase
NFAT inhibitor, Cell Permeable aceate
TP1978L
Synonym:
Target: Others
Procyanidin B2
T6S1367
Synonym: Proanthocyanidin B2
Target: Reactive Oxygen Species, NOD
Phenacetin
T0778
Synonym: Acetophenetidin
Target: COX
Apararenone
T14301
Synonym: MT-3995
Target: Glucocorticoid Receptor
dencichine
TL0001
Synonym: L-Dencichin,ODAP,Dencichin
Target: Others, HIF/HIF Prolyl-Hydroxylase
KS370G
T24270
Synonym: KS-370-G,KS 370 G,Caffeic Acid Phenethyl Amide
Target:
MTP 131 acetate
T35689
Synonym:
Target: Others
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TargetMol