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Imidapril hydrochloride

Imidapril hydrochloride (Tanapril) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension.

Catalog No. T6542Cas No. 89396-94-1

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Purity:99.94%

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COA HNMR HPLC

Imidapril hydrochloride

Catalog No. T6542Cas No. 89396-94-1

Imidapril hydrochloride (Tanapril) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension.

With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.

Pack Size	Price	Availability
5 mg	$39	In Stock
10 mg	$53	In Stock
25 mg	$96	In Stock
50 mg	$163	In Stock
100 mg	$243	In Stock
200 mg	$362	In Stock
1 mL x 10 mM (in DMSO)	$52	In Stock

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Product Introduction

Bioactivity

Description	Imidapril hydrochloride (Tanapril) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension.
Targets&IC50	ACE:2.6 nM
Alias	Novaloc, Imidapril HCl, Tanapril, TA-6366

Chemical Properties

Molecular Weight	441.91
Formula	C₂₀H₂₇N₃O₆·HCl
Cas No.	89396-94-1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

H2O: 50 mg/mL (113.1 mM)

DMSO: 82 mg/mL (185.6 mM)

Ethanol: 28 mg/mL (63.4 mM)

Solution Preparation Table

Ethanol/H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2629 mL	11.3145 mL	22.6290 mL	113.1452 mL
5 mM	0.4526 mL	2.2629 mL	4.5258 mL	22.6290 mL
10 mM	0.2263 mL	1.1315 mL	2.2629 mL	11.3145 mL
20 mM	0.1131 mL	0.5657 mL	1.1315 mL	5.6573 mL
50 mM	0.0453 mL	0.2263 mL	0.4526 mL	2.2629 mL

H2O/DMSO

	1mg	5mg	10mg	50mg
100 mM	0.0226 mL	0.1131 mL	0.2263 mL	1.1315 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc