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Imidapril hydrochloride

Catalog No. T6542 CAS 89396-94-1

Synonyms: Imidapril HCl, TA-6366, Tanapril, Novaloc

Imidapril HCl is an Angiotensin-converting Enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension.

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Imidapril hydrochloride, CAS 89396-94-1

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Imidapril HCl is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension.
Targets&IC50	ACE:2.6 nM

Synonyms	Imidapril HCl, TA-6366, Tanapril, Novaloc
Molecular Weight	441.91
Formula	C20H27N3O6·HCl
CAS No.	89396-94-1

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

Ethanol: 28 mg/mL (63.4 mM)

H2O: 50 mg/mL (113.1 mM)

DMSO: 82 mg/mL (185.6 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Thoulon F, Woehrlé F, Boisramé B.J Vet Cardiol. 2003 May;5(1):29-34

Dose Conversion

You can also refer to dose conversion for different animals. More

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Imidapril hydrochloride 89396-94-1 Endocrinology/Hormones RAAS Imidapril HCl TA6366 nephropathy TA-6366 MMP type 1 diabetic Inhibitor Angiotensin-converting Enzyme (ACE) Matrix metalloproteinases Tanapril TA 6366 chronic heart failure Imidapril angiotensin inhibit antihypertensive Novaloc inhibitor

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