kidney — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8134	Cefathiamidine		Antibacterial , Antibiotic
	Cefathiamidine exhibits a wide spectrum of antimicrobial activity against bacteria. Cefathiamidine is used for the treatment of respiratory, liver, five senses, urinary tract infections, endocarditis and sepsis		Antibacterial , Antibiotic
T27246	EG1		Others
	EG1, a novel specific inhibitor of Pax2 transcription activation, targets the DNA binding domain and inhibits embryonic kidney development.		Others
T37596	Terevalefim		c-Met/HGFR
	Terevalefim (ANG-3777) is an hepatocyte growth factor (HGF) mimetic. Terevalefim selectively activates the c-Met receptor.		c-Met/HGFR
TP1187	C-Type Natriuretic Peptide (CNP) (1-22), human	CNP (1-22), human	RAAS
	C-Type Natriuretic Peptide (CNP) (1-22), human is the 1-22 fragment of C-Type Natriuretic Peptide.		RAAS
T16724	Razuprotafib	AKB-9778	Phosphatase , Others
	Razuprotafib (AKB-9778) is a protein tyrosine phosphatase ß (HPTPß) inhibitor (IC50: 50 nM). Razuprotafib is effective for the activation of Tie-2 and is protective against acute kidney injury.		Phosphatase , Others
T23133	Pentamidine		Phosphatase , Antibacterial , Antibiotic , Parasite , Antifungal
	Pentamidine is an antifungal and antiprotozoal agent, interacting directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor groove of DNA, thereby interfering with DNA replication.
T9615	CK7		CDK
	CK7, a Cdk2/9 inhibitor, is instrumental in the synthesis of Nek1 inhibitors BSc5231 and BSc5367.		CDK
T2S1837	Steviol	NSC 226902,Hydroxydehydrostevic acid	Others
	1. Steviol (NSC-226902), a natural sweetener, it inhibits proliferation of the gastrointestinal cancer cells intensively. 2. Steviol can induce a significant increase in CYP3A29 expression. 3. Steviol inhibits the prolif...		Others
T7802	M1001		HIF/HIF Prolyl-Hydroxylase , HIF
	M1001 is a HIF-2α agonist.		HIF/HIF Prolyl-Hydroxylase , HIF
T22428	Sodium Glucoheptonate	Sodium glucoheptonate	Others
	Sodium Glucoheptonate (Sodium glucoheptonate) is used as a kit for radio-labeling with Tc-99m which is kidney- and brain-imaging agent, and can be used in brain-tumor detection[1][2]. Sodium glucoheptonate is also used f...		Others
T14002	12-Ketodeoxycholic acid		Endogenous Metabolite
	12-Ketodeoxycholic acid, a bile acid and kidney metabolite, serves as a detectable marker for kidney injury [1].		Endogenous Metabolite
T8528	AC1903		TRP/TRPV Channel
	AC1903 is a specific inhibitor of TRPC5 channel, and has been shown to suppress severe proteinuria and prevent podocyte loss.		TRP/TRPV Channel
T11394	GFB-8438		TRP/TRPV Channel
	GFB-8438 is a potent and subtype selective inhibitor of TRPC5(IC50s of 0.18 and 0.29 μM of hTRPC5 and hTRPC4, respectively).		TRP/TRPV Channel
T9022	AZD9977	AZD 9977	Glucocorticoid Receptor
	AZD9977 is a novel, selective modulator of mineralocorticoid receptor .		Glucocorticoid Receptor
T1313	Nitrofurantoin	Furadantine,Macrodantin,Furadonine	Antibacterial , Antibiotic
	Nitrofurantoin (Furadantine), an antibiotic, inhibits bacterial DNA, RNA, and cell wall protein synthesis. Activated by bacterial flavoproteins to intermediates that inactivate bacterial ribosomal proteins, Nitrofurantoi...		Antibacterial , Antibiotic
T28410	PHPS1	PHPS-1,PHPS 1	Phosphatase
	PHPS1 is an inhibitor of Shp2. PHPS1 efficiently inhibits activation of Erk1/2 by the leukemia-associated Shp2 mutant, Shp2-E76K, and blocks the anchorage-independent growth of a variety of human tumor cell lines.		Phosphatase
T1874	PPQ-102	PPQ102,CFTR Inhibitor,PPQ 102	CFTR , Autophagy
	PPQ-102 (CFTR Inhibitor), an effective CFTR inhibitor, can completely inhibit CFTR chloride current (IC50: 90 nM).		CFTR , Autophagy
T6848	GSK1016790A	GSK101	Calcium Channel , TRP/TRPV Channel
	GSK1016790A (GSK101) (GSK101) is a novel, potent activator of TRPV4 (transient receptor potential vanilloid 4) with EC50 of 34 nM in choroid plexus epithelial cells.		Calcium Channel , TRP/TRPV Channel
T8930	CID44216842	KUC103479N-02	CDK , Ras
	CID44216842 (KUC103479N-02) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT...		CDK , Ras
T12883	Fezagepras	PBI-4050,Setogepram	GPR
	Fezagepras (Setogepram) is an orally active GPR40 agonist and is an antagonist or inverse agonist of GPR84 with anti-inflammatory, anti-fibrotic, and anti-proliferative actions.		GPR