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Search Results for " ischemic "

20

Compounds

Cat No. Product Name Synonyms Targets
T15130 Dilazep dihydrochloride Others
Dilazep dihydrochloride is an adenosine uptake inhibitor. It also inhibits ischemic damage, membrane transport of nucleosides, and platelet aggregation. It has cerebral and coronary vasodilating action through the enhanc...
TP1856 Colivelin Beta Amyloid , STAT
Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN).
T2423 P7C3-A20 Others
P7C3-A20 is a derivative of P7C3 that has proneurogenic and neuroprotective activity.
T7946 AER-271 Aquaporin
AER-271 is an inhibitor of aquaporin-4.
T22749 DR2313 DR 2313 PARP
DR2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (IC50: 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). It also has neuroprotective.
T39341 FCPR03 PDE
FCPR03 is a selective inhibitor of phosphodiesterase 4 (PDE4) with IC50s of 31 nM, 47 nM, and 60 nM for PDE4B1, PDE4D7, and PDE4 catalytic domain, respectively. FCPR03 has neuroprotective, anti-inflammatory, and antidepr...
T8869 B355252 Others
B355252 protects against cell death caused by glutamate-evoked oxidative stress. B355252 shows neuroprotective effect, potentiating nerve growth factor (NGF)-induced neurite outgrowth.
T5326 Sugammadex sodium Org25969,Sugammadex (sodium) Others
Sugammadex sodium (Org25969) , a synthetic derivative of γ-cyclodextrin, is a steroid-based neuromuscular blocker reversing agent.
T3074 CHIR 98024 CHIR98014 GSK-3 , S6 Kinase
CHIR 98024 is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM in cell-free assays, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2.
T20843 Aplodan Nergize,Creatinolfosfate,creatinol-O-phosphate,Creatinolfosfate, Creatinol Phosphate Others
Aplodan (creatinol-O-phosphate) exhibits antiischemic and antiarrhythmic capacity and protective action on the cell membrane. Aplodan can be used in research on the ischemic heart or ischemic heart disease with persisten...
T23146 PHA 568487 free base PHA 568487 AChR
The quinuclidine PHA 568487 free base is an agonist of the alpha 7 nicotinic acetylcholine receptor that was designed to mitigate the bioactivation associated with the core scaffold and subsequently remove associated lia...
T0368 Cinepazide maleate MD-67350,Vasodistal,Brendil Calcium Channel
Cinepazide maleate (MD-67350), a maleate salt form of cinepazide, is a vasodilator.
T0154 Nebivolol hydrochloride R 065824 hydrochloride,Nebivolol HCl,R-65824 Apoptosis , Adrenergic Receptor
Nebivolol hydrochloride (R 065824 hydrochloride) is a cardioselective ADRENERGIC BETA-1 RECEPTOR ANTAGONIST (beta-blocker) that functions as a VASODILATOR through the endothelial L-arginine/ NITRIC OXIDE system. It is us...
T6595 Moexipril hydrochloride Moexipril HCl,RS-10085,SPM 925,CI-925 Apoptosis , RAAS
Moexipril hydrochloride (Moexipril HCl) is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment of hypertension and congestive heart failure.
T39195 YM-244769 dihydrochloride Calcium Channel
YM-244769 dihydrochloride is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3) with an IC50 of 18 nM. YM-244769 dihydrochloride has efficient protective effects on neurons and kidneys.
T9888 YM-244769 3-Pyridinecarboxamide, N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]- Calcium Channel
YM-244769 (3-Pyridinecarboxamide, N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]-) is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3) with an IC50 of 18 nM. YM-244769 has efficient protective effec...
T19659 Annaosanchun YC6,YC-6,YC 6 Others , AMPK
Annaosanchun (YC-6) is potentially for the treatment of acute ischemic stroke (AIS).
T19466 N8-Acetylspermidine dihydrochloride Endogenous Metabolite
N8-Acetylspermidine dihydrochloride is a polyamine.
T29687 Afacifenacin Afacifenacin fumarate,SMP-986,NS 986,NS-986,SMP 986,NS986,SMP986 AChR
Afacifenacin (SMP-986) fumarate is an M3 muscarinic receptor-selective antagonist used in the study of ischemic heart disease, urinary incontinence and cystitis and other disorders.
T39463 Asundexian BAY 2433334,Asundexian,BAY2433334,BAY-2433334 Factor Xa
Asundexian (BAY-2433334) is a potent and orally active inhibitor of the coagulation factor FXIa that directly and reversibly binds to the active site of FXIa, thereby inhibiting its activity.Asundexian has an IC50 of 1 n...
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