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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15130 | Dilazep dihydrochloride | Others | |
Dilazep dihydrochloride is an adenosine uptake inhibitor. It also inhibits ischemic damage, membrane transport of nucleosides, and platelet aggregation. It has cerebral and coronary vasodilating action through the enhanc... | |||
TP1856 | Colivelin | Beta Amyloid , STAT | |
Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN). | |||
T2423 | P7C3-A20 | Others | |
P7C3-A20 is a derivative of P7C3 that has proneurogenic and neuroprotective activity. | |||
T7946 | AER-271 | Aquaporin | |
AER-271 is an inhibitor of aquaporin-4. | |||
T22749 | DR2313 | DR 2313 | PARP |
DR2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (IC50: 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). It also has neuroprotective. | |||
T39341 | FCPR03 | PDE | |
FCPR03 is a selective inhibitor of phosphodiesterase 4 (PDE4) with IC50s of 31 nM, 47 nM, and 60 nM for PDE4B1, PDE4D7, and PDE4 catalytic domain, respectively. FCPR03 has neuroprotective, anti-inflammatory, and antidepr... | |||
T8869 | B355252 | Others | |
B355252 protects against cell death caused by glutamate-evoked oxidative stress. B355252 shows neuroprotective effect, potentiating nerve growth factor (NGF)-induced neurite outgrowth. | |||
T5326 | Sugammadex sodium | Org25969,Sugammadex (sodium) | Others |
Sugammadex sodium (Org25969) , a synthetic derivative of γ-cyclodextrin, is a steroid-based neuromuscular blocker reversing agent. | |||
T3074 | CHIR 98024 | CHIR98014 | GSK-3 , S6 Kinase |
CHIR 98024 is a potent GSK-3α/β inhibitor with IC50 of 0.65 nM/0.58 nM in cell-free assays, with the ability to distinguish GSK-3 from its closest homologs Cdc2 and ERK2. | |||
T20843 | Aplodan | Nergize,Creatinolfosfate,creatinol-O-phosphate,Creatinolfosfate, Creatinol Phosphate | Others |
Aplodan (creatinol-O-phosphate) exhibits antiischemic and antiarrhythmic capacity and protective action on the cell membrane. Aplodan can be used in research on the ischemic heart or ischemic heart disease with persisten... | |||
T23146 | PHA 568487 free base | PHA 568487 | AChR |
The quinuclidine PHA 568487 free base is an agonist of the alpha 7 nicotinic acetylcholine receptor that was designed to mitigate the bioactivation associated with the core scaffold and subsequently remove associated lia... | |||
T0368 | Cinepazide maleate | MD-67350,Vasodistal,Brendil | Calcium Channel |
Cinepazide maleate (MD-67350), a maleate salt form of cinepazide, is a vasodilator. | |||
T0154 | Nebivolol hydrochloride | R 065824 hydrochloride,Nebivolol HCl,R-65824 | Apoptosis , Adrenergic Receptor |
Nebivolol hydrochloride (R 065824 hydrochloride) is a cardioselective ADRENERGIC BETA-1 RECEPTOR ANTAGONIST (beta-blocker) that functions as a VASODILATOR through the endothelial L-arginine/ NITRIC OXIDE system. It is us... | |||
T6595 | Moexipril hydrochloride | Moexipril HCl,RS-10085,SPM 925,CI-925 | Apoptosis , RAAS |
Moexipril hydrochloride (Moexipril HCl) is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment of hypertension and congestive heart failure. | |||
T39195 | YM-244769 dihydrochloride | Calcium Channel | |
YM-244769 dihydrochloride is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3) with an IC50 of 18 nM. YM-244769 dihydrochloride has efficient protective effects on neurons and kidneys. | |||
T9888 | YM-244769 | 3-Pyridinecarboxamide, N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]- | Calcium Channel |
YM-244769 (3-Pyridinecarboxamide, N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]-) is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3) with an IC50 of 18 nM. YM-244769 has efficient protective effec... | |||
T19659 | Annaosanchun | YC6,YC-6,YC 6 | Others , AMPK |
Annaosanchun (YC-6) is potentially for the treatment of acute ischemic stroke (AIS). | |||
T19466 | N8-Acetylspermidine dihydrochloride | Endogenous Metabolite | |
N8-Acetylspermidine dihydrochloride is a polyamine. | |||
T29687 | Afacifenacin | Afacifenacin fumarate,SMP-986,NS 986,NS-986,SMP 986,NS986,SMP986 | AChR |
Afacifenacin (SMP-986) fumarate is an M3 muscarinic receptor-selective antagonist used in the study of ischemic heart disease, urinary incontinence and cystitis and other disorders. | |||
T39463 | Asundexian | BAY 2433334,Asundexian,BAY2433334,BAY-2433334 | Factor Xa |
Asundexian (BAY-2433334) is a potent and orally active inhibitor of the coagulation factor FXIa that directly and reversibly binds to the active site of FXIa, thereby inhibiting its activity.Asundexian has an IC50 of 1 n... |