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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9026 | MEISi-2 | Benzoic acid, 4-hydroxy-, 2-[(Z)-(2-oxo-1(2H)-naphthalenylidene)methyl]hydrazide | Others |
MEISi-2 is a potent MEIS inhibitor (MEISi). MEISi-2 significantly inhibits MEIS-luciferase reporters in vitro. | |||
T28978 | Tirilazad mesylate | U-74006 mesylate,U74006 mesylate,U 74006 mesylate,U 74006F mesylate,U-74006F mesylate,U74006F mesylate | Antiviral |
Tirilazad mesylate (U 74006F) is a non-glucocorticoid, lipid peroxidation inhibitor with antiviral activity and neuroprotective activity.Tirilazad mesylate confines intracellular intramembranous foci, attenuates spinal c... | |||
TQ0131 | Rocaglamide | Rocaglamide A,Roc-A | HSP , NF-κB , PERK |
Rocaglamide (Roc-A), isolated from the genus Aglaia, can be used to treat coughs, injuries, asthma, and inflammatory skin diseases. It is a potent inhibitor of NF-κB activation in T-cells. | |||
T0897 | Nitrofurazone | NFZ,Nitrofural,Furacilin | Dehydrogenase , Antibacterial , Glutathione reductase , Antibiotic |
Nitrofurazone (Furacilin) is a topical anti-infective agent effective against gram-negative and gram-positive bacteria. It is used for superficial WOUNDS AND INJURIES and skin infections. Nitrofurazone(NFZ) has also been... | |||
T10112 | 3-Hydroxy-4-methoxyacetophenone | Acetoisovanillone | Others |
3-Hydroxy-4-methoxyacetophenone (Acetoisovanillone) is an active P. spinosa extract. It possesses anti-inflammatory activity and prevented injuries due to administration of acetic acid in the colon. | |||
T4065 | Fluorescein Sodium | Fluorescite,VST-1001,Acid yellow 73,VST1001,VST 1001 | Others |
Fluorescein Sodium (VST-1001) is a phthalic indicator dye. It is used therapeutically as a diagnostic aid in corneal injuries and corneal trauma. | |||
T8630 | Baclofen hydrochloride | 4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride | GABA Receptor |
Baclofen hydrochloride (4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride) is a GAMMA-AMINOBUTYRIC ACID derivative that is a specific GABA-B RECEPTORS agonist. It is used in the treatment of MUSCLE SPASTICITY, espe... | |||
T22346 | Indomethacin sodium hydrate | Indometacin sodium hydrate | COX |
Indomethacin sodium hydrate (Indometacin sodium hydrate) is an orally active, competitive and reversible COX1/2 inhibitor with potential anti-inflammatory activity in induced migraines, induced gastrointestinal injuries,... | |||
T5030 | Zofenopril calcium | SQ26991,Zofenopril (calcium) | RAAS , Reactive Oxygen Species |
Zofenopril calcium (SQ26991) is an antioxidant that acts as an angiotensin-converting enzyme inhibitor. ACE Zofenopril is a pro-drug designed to undergo metabolic hydrolysis yielding the active free sulfhydryl compound z... | |||
T2836 | Isorhamnetin | 3-methylquercetin,3'-Methylquercetin,Isorhamnetol,3'-Methoxyquercetin | MEK , PI3K , Endogenous Metabolite |
Isorhamnetin (3-methylquercetin) is the methylated metabolite of quercetin. Quercetin is an important dietary flavonoid with in vitro antioxidant activity. Isorhamnetin prevents endothelial cell injuries from oxidized LD... | |||
T21338 | Methylprednisolone Acetate | Depo-Medrate,Depometicort,Depo-Medrin,Depo-medrol,Depomedrone,Lemod | Reactive Oxygen Species |
Methylprednisolone Acetate(Depo-Medrate) has the ability to inhibit oxygen free radicals and can be used to treat acute spinal cord injuries. | |||
TN5278 | Zederone | NADPH-oxidase , P450 , TNF , Nrf2 , Antifection | |
Zederone has anti-bacterial activity,it inhibits gram-positive bacteria activity. Zederone induces hepatotoxicity implicated the induction of Cyps, which leads to the formation of biological reactive metabolites and that... | |||
T60260 | Phenazopyridine | ||
Phenazopyridine is commonly utilized as a local analgesic to mitigate pain, irritation, discomfort, or urgency resulting from urinary tract infections, surgical procedures, or injuries affecting the urinary tract [1]. | |||
T70145 | LYRM03 | ||
LYRM03 is an aminopeptidase inhibitor. LYRM03 is also an ubenimex derivative. LYRM03 attenuates LPS-induced acute lung injury in mice by suppressing the TLR4 signaling pathway. LYRM03 effectively attenuates LPS-induced A... | |||
T80419 | TAT-NEP1-40 TFA | Apoptosis | |
TAT-NEP1-40 TFA, a blood-brain barrier-permeable peptide, safeguards PC12 cells against oxygen and glucose deprivation (OGD) and fosters neurite outgrowth. Additionally, it enhances neurological outcomes post-ischemia by... | |||
T83825 | Trofinetide acetate | NNZ-2566 | |
Trofinetide, derived from the neuroprotective tripeptide Gly-Pro-Glu (an N-terminal sequence of insulin-like growth factor-1, IGF-1), shows promise in various neuroprotective models. At a concentration of 10 nM, it mitig... |