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Tirilazad mesylate

Catalog No. T28978 CAS 110101-67-2

Synonyms: U-74006 mesylate, U74006 mesylate, U 74006 mesylate, U 74006F mesylate, U-74006F mesylate, U74006F mesylate

Tirilazad mesylate (U 74006F) is a non-glucocorticoid, lipid peroxidation inhibitor with antiviral activity and neuroprotective activity.Tirilazad mesylate confines intracellular intramembranous foci, attenuates spinal cord injury induced by trauma, stroke, and ischemia/reperfusion injuries, inhibits toxins in dogs, reduces the effects of Tirilazad mesylate is used in the study of neurological disorders.

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Tirilazad mesylate, CAS 110101-67-2

Pack Size	Availability	Price/USD
5 mg	In stock	$ 1,270.00
50 mg	In stock	$ 2,580.00
100 mg	In stock	$ 3,400.00

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Purity: 99.65%

ee: 100%

Purity: 99.48%

ee: 100%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	U-74006 mesylate, U74006 mesylate, U 74006 mesylate, U 74006F mesylate, U-74006F mesylate, U74006F mesylate
Molecular Weight	720.96
Formula	C39H56N6O5S
CAS No.	110101-67-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 33.33 mg/mL (46.23 mM), Sonication is recommended.

References and Literature

1. Tirilazad mesylate in acute ischemic stroke: A systematic review. Tirilazad International Steering Committee. Stroke. 2000 Sep;31(9):2257-65. 2. Zhang S, et al. Tirilazad for aneurysmal subarachnoid haemorrhage. Cochrane Database Syst Rev. 2010 Feb 17;(2):CD006778. 3. Bath PM, et al. Tirilazad for acute ischaemic stroke. Cochrane Database Syst Rev. 2001;(4):CD002087. 4. Jang YG, Ilodigwe D, Macdonald RL. Metaanalysis of tirilazad mesylate in patients with aneurysmal subarachnoid hemorrhage. Neurocrit Care. 2009;10(1):141-7. doi: 10.1007/s12028-008-9147-y. Epub 2008 Sep 23. PubMed PMID: 18810661.

Related compound libraries

This product is contained In the following compound libraries：

Drug Repurposing Compound Library Inhibitor Library

Related Products

Related compounds with same targets

AMC-01 Bruceine D LHF-535 DDG-39 BTA-188 A2ti-2 Pleconaril MK-28

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Tirilazad mesylate 110101-67-2 Immunology/Inflammation Antiviral U 74006F U74006 U-74006 mesylate U 74006 Tirilazad Mesylate U74006 mesylate U74006F U 74006 mesylate U 74006F mesylate U-74006 U-74006F mesylate U-74006F U74006F mesylate inhibitor inhibit

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