infarction — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2320	Indacaterol		Adrenergic Receptor
	Indacaterol (Onbrez; Arcapta) is a β2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist.		Adrenergic Receptor
T15108	DG-041		Prostaglandin Receptor
	DG-041 is an antagonist of high-affinity EP3 receptor (IC50s: 4.6 nM and 8.1 nM in the binding and FLIPR assay, respectively). DG-041 inhibits PGE2 facilitation of platelet aggregation and has the blood-brain barrier per...		Prostaglandin Receptor
T4330	CaCCinh-A01		Chloride channel
	CaCCinh-A01 is an inhibitor of the calcium-activated chloride channel (CaCC, 10 μM) and TMEM16A (IC50: 2.1 μM).		Chloride channel
T3461	Losartan Carboxylic Acid	EXP-3174,E-3174	RAAS
	Losartan Carboxylic Acid (E-3174) a potent AT1 antagonist (Kis: 0.57 nM, rat; 0.67 nM, human), producing a depressor response and vasodilatation. Losartan Carboxylic Acid , a metabolite of losartan, is more potent than l...		RAAS
T1239	Indacaterol maleate	QAB149	Adrenergic Receptor
	Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist.		Adrenergic Receptor
T1479	Isosorbide dinitrate	Isordil,Nitrosorbide,Sorbide nitrate,Sorbidnitrate	Others , NO Synthase
	Isosorbide dinitrate (Isordil) is a vasodilator used in the treatment of angina pectoris.		Others , NO Synthase
T15418	GS-6201	CVT-6883	Adenosine Receptor
	GS-6201 (CVT-6883) is a selective antagonist of adenosine A2B receptor. GS-6201 shows high affinity and selectivity for the human adenosine A2B receptors with a Ki of 22 nM.		Adenosine Receptor
T5329	Trandolapril		Angiotensin-converting Enzyme (ACE)
	Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that is hydrolysed to the active diacid trandolaprilat.		Angiotensin-converting Enzyme (ACE)
T7714	Temocapil		Tyrosinase
	Temocapril is an inhibitor of tyrosine kinase.		Tyrosinase
T2893	Muscone	3-Methylcyclopentadecanone,Methylexaltone	MMP , TNF , NF-κB , NOD-like Receptor (NLR) , P-gp , Interleukin
	Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk.
T3230	NLRP3-IN-2	5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide,NLRP3 Inflammasome Inhibitor I	NOD-like Receptor (NLR) , NOD
	NLRP3-IN-2 (5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide), an intermediate capable of synthesizing glibenclamide, exerts an inhibitory effect on the formation of NLRP3 inflammatory vesicles in cardiomyocytes, limiting i...		NOD-like Receptor (NLR) , NOD
T6698	Temocapril hydrochloride	CS-622 HCl,Acecol,Temocapril HCl,CS-622	RAAS
	Temocapril hydrochloride (CS-622 HCl), the hydrochloride of Temocapril, is a long-acting ACE inhibitor used for the therapy of hypertension.		RAAS
T67941	PDE5-IN-9
	PDE5-IN-9 inhibits Phosphodiesterase PDE1c and is used to treat hypertension, heart failure, myocardial infarction, kidney failure, asthma, bronchitis, and dementia.
T11239	Ethacizine hydrochloride	NIK-244,Ethacizin,NIK-244 hydrochloride	Sodium Channel
	Ethacizine hydrochloride (NIK-244) has antiarrhythmic activity, and its effects are related to cardiac activity and can be used to study arrhythmias and myocardial infarction.		Sodium Channel
T3S0289	Araloside X		Calcium Channel
	Aralosides possess protective effect against experimental myocardial ischemia and infarction, the mechanism of myocardial protection may be attributed to the amelioration of FFA metabolic deterioration and membrane perox...		Calcium Channel
T24115	GSK854	GSK-854,GSK 854	Apoptosis
	GSK854 is a highly selective and potent inhibitor of troponin I interacting kinase (TNNI3K) that inhibits myocardial infarction-injured cellular pyroptosis and apoptosis in mice, which may limit oxidative stress, injury,...		Apoptosis
T0407	Edaravone	MCI-186	Apoptosis , MMP , Free radical scavengers
	Edaravone (MCI-186)(MCI-186) is a potent new free radical scavenger used for the therapy of patients with acute brain infarction.		Apoptosis , MMP , Free radical scavengers
T68022L	Sulotroban potassium	BM 13177 potassium,Sulotroban potassium(72131-33-0 Free base)	PPAR
	Sulotroban potassium is a small molecule thromboxane A2 receptor (TXA2R) antagonist that can be used to study myocardial infarction and thrombosis.		PPAR
T83977	BIIB 722 Mesylate		Sodium Channel
	BIIB 722 Mesylate is a selective sodium-hydrogen exchange inhibitor with cardioprotective properties and can be used to study myocardial ischemia and myocardial infarction.		Sodium Channel
T77611	DAPK-IN-2	WAY-380496	DAPK
	DAPK-IN-2 (WAY-380496) is a DAPK inhibitor. DAPK-IN-2 has potential anticancer activity, regulates autophagy and can be used to study cerebral infarction and ischemic diseases.		DAPK