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NLRP3-IN-2

NLRP3-IN-2
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Purity:98.98%
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NLRP3-IN-2

Catalog No. T3230Cas No. 16673-34-0
NLRP3-IN-2 (5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide), an intermediate capable of synthesizing glibenclamide, exerts an inhibitory effect on the formation of NLRP3 inflammatory vesicles in cardiomyocytes, limiting infarct size after myocardial ischemia/reperfusion in mice and has no effect on metabolism.
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Pack SizePriceAvailabilityQuantity
50 mg$41In Stock
100 mg$53In Stock
200 mg$76In Stock
1 mL x 10 mM (in DMSO)$45In Stock
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Product Introduction

Bioactivity
Description
NLRP3-IN-2 (5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide), an intermediate capable of synthesizing glibenclamide, exerts an inhibitory effect on the formation of NLRP3 inflammatory vesicles in cardiomyocytes, limiting infarct size after myocardial ischemia/reperfusion in mice and has no effect on metabolism.
Alias5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide, NLRP3 Inflammasome Inhibitor I
Chemical Properties
Molecular Weight368.84
FormulaC16H17ClN2O4S
Cas No.16673-34-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 55 mg/mL (149.12 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7112 mL13.5560 mL27.1120 mL135.5601 mL
5 mM0.5422 mL2.7112 mL5.4224 mL27.1120 mL
10 mM0.2711 mL1.3556 mL2.7112 mL13.5560 mL
20 mM0.1356 mL0.6778 mL1.3556 mL6.7780 mL
50 mM0.0542 mL0.2711 mL0.5422 mL2.7112 mL
100 mM0.0271 mL0.1356 mL0.2711 mL1.3556 mL

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