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NLRP3-IN-2
🥰Excellent
Catalog No. T3230Cas No. 16673-34-0
Alias NLRP3 Inflammasome Inhibitor I, 5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide
NLRP3-IN-2 (5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide), an intermediate capable of synthesizing glibenclamide, exerts an inhibitory effect on the formation of NLRP3 inflammatory vesicles in cardiomyocytes, limiting infarct size after myocardial ischemia/reperfusion in mice and has no effect on metabolism.
NLRP3-IN-2
🥰Excellent
Purity: 98.98%
Catalog No. T3230Alias NLRP3 Inflammasome Inhibitor I, 5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamideCas No. 16673-34-0
NLRP3-IN-2 (5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide), an intermediate capable of synthesizing glibenclamide, exerts an inhibitory effect on the formation of NLRP3 inflammatory vesicles in cardiomyocytes, limiting infarct size after myocardial ischemia/reperfusion in mice and has no effect on metabolism.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 mg | $41 | In Stock | |
| 100 mg | $53 | In Stock | |
| 200 mg | $76 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $45 | In Stock |
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Purity:98.98%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | NLRP3-IN-2 (5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide), an intermediate capable of synthesizing glibenclamide, exerts an inhibitory effect on the formation of NLRP3 inflammatory vesicles in cardiomyocytes, limiting infarct size after myocardial ischemia/reperfusion in mice and has no effect on metabolism. |
| Alias | NLRP3 Inflammasome Inhibitor I, 5-Chloro-N-(p-sulfamoylphenethyl)-o-anisamide |
| Molecular Weight | 368.84 |
| Formula | C16H17ClN2O4S |
| Cas No. | 16673-34-0 |
| Smiles | COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)S(N)(=O)=O |
| Relative Density. | 1.356g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (149.12 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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