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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN4660 | Niranthin | Anti-infection , HBV , PAFR , Topoisomerase | |
Niranthin is a potent anti-leishmanial agent, inhibits the relaxation activity of heterodimeric type IB topoisomerase of L. donovani and acts as a non-competitive inhibitor interacting with both subunits of the enzyme. N... | |||
T4989 | Fosfomycin Tromethamine | Antibacterial , Antibiotic | |
An antibiotic produced by Streptomyces fradiae. | |||
T8722 | IKIX1 | Antifungal | |
iKIX1 is an Pdr1-dependent gene activation. It re-sensitizes drug-resistant C. glabrata to azole antifungals in vitro and in animal models for disseminated and urinary tract C. glabrata infection. | |||
TN6512 | Tectol | Transferase , Parasite | |
Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 3.44±0.20μM. It exhibited significant activity against human leukemia cell lines HL60 and CEM. Tectol may cause itchy dermatiti... | |||
T9014 | SKI-178 | Apoptosis , S1P Receptor | |
SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor with IC50 of 0.1-1.8 μM. It induces prolonged mitosis followed by apoptotic cell death through the intrinsic apoptotic cascade. The sustained activation of CDK1 during ... | |||
T3131 | Fosfomycin calcium | Phosphomycin calcium salt,Fosmicin | Antibacterial , Antibiotic |
Fosfomycin calcium (Phosphomycin calcium salt) is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis. | |||
T8262 | Fosfomycin sodium | Fosfomycin Disodium | Antibacterial , Antibiotic |
Fosfomycin sodium is a bactericidal, low-molecular weight, broad-spectrum antibiotic, with putative activity against several bacteria, including multidrug-resistant Gram-negative bacteria, by irreversibly inhibiting an e... | |||
T8217 | Enzalutamide carboxylic acid | Androgen Receptor , Drug Metabolite | |
Enzalutamide carboxylic acid is an antagonist of androgen receptor (AR) . | |||
T10981 | DCZ0415 | Apoptosis , Others , NF-κB | |
DCZ0415 induces antimyeloma activity in vitro, in vivo and in primary cells of drug-resistant myeloma patients. DCZ0415 is a potent TRIP13 inhibitor that can impair the repair of non-homologous end junctions and inhibit ... | |||
T9830 | GSK2556286 | GSK286 | Antibacterial |
GSK2556286 (GSK286) is an orally active inhibitor of Mycobacterium tuberculosis (M. tuberculosis).GSK2556286 inhibits the growth of human macrophages with an IC50 value of 0.07 μM.GSK2556286 is effective against both mul... | |||
T10378 | Artelinic acid | Others | |
Artelinic acid, a derivative of Artemisinin, is an antimalarial drug for the treatment of multidrug-resistant strains of Plasmodium falciparum. | |||
T10356 | AQ-13 dihydrochloride | Parasite | |
AQ-13 dihydrochloride is an antimalarial drug. It is effective against drug-resistant strains of Plasmodium falciparum. | |||
T64860 | 3-(Trifluoromethyl)cinnamic acid | 3-(3-(Trifluoromethyl)phenyl)acrylic acid | Antibiotic |
3-(Trifluoromethyl)cinnamic acid (3-(3-(Trifluoromethyl)phenyl)acrylic acid) can be used to study drug-resistant bacterial infections. | |||
T14081 | Enmetazobactam | AAI101 | Antibacterial |
Enmetazobactam (AAI101) is an extended-spectrum β-lactamase inhibitor for the treatment of multi-drug resistant gram-negative bacterial infections. | |||
T22269 | Benzyldodecyldimethylammonium Chloride Dihydrate | Antibacterial | |
Benzyldodecyldimethylammonium chloride dihydrate can be used as an insecticide reagent. It can target drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, multidrug-resistant Pseudomonas aerugino... | |||
T5315 | TCA1 | TCA-1,TCA 1 | Antibacterial , Antibiotic |
TCA1 (TCA 1) is a small molecule with activity against drug-resistant and persistent tuberculosis. | |||
T73586 | Anticonvulsant agent 2 | Others | |
Anticonvulsant agent 2 is a potent orally active anticonvulsant that has shown antiepileptic activity in a model of drug-resistant epilepsy. | |||
TQ0152 | Dalfopristin | RP54476 | Antibacterial , Antibiotic |
Dalfopristin (RP54476) is a semi-synthetic streptogramin antibiotic. Quinupristin/Dalfopristin (Q/D) is used for the treatment of multi-drug resistant Enterococcus faecium infections. | |||
T6824 | EAI045 | EGFR | |
EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor. | |||
T0391 | Linezolid | PNU-100766 | MAO , Antibacterial , Antibiotic |
Linezolid (PNU-100766), the first of the oxazolidinone class, is a synthetic antibiotic used for the therapy of infections resulted from multi-resistant bacteria including methicillin-resistant Staphylococcus aureus (MRS... |