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Search Results for " drug-resistant "

20

Compounds

Cat No. Product Name Synonyms Targets
TN4660 Niranthin Anti-infection , HBV , PAFR , Topoisomerase
Niranthin is a potent anti-leishmanial agent, inhibits the relaxation activity of heterodimeric type IB topoisomerase of L. donovani and acts as a non-competitive inhibitor interacting with both subunits of the enzyme. N...
T4989 Fosfomycin Tromethamine Antibacterial , Antibiotic
An antibiotic produced by Streptomyces fradiae.
T8722 IKIX1 Antifungal
iKIX1 is an Pdr1-dependent gene activation. It re-sensitizes drug-resistant C. glabrata to azole antifungals in vitro and in animal models for disseminated and urinary tract C. glabrata infection.
TN6512 Tectol Transferase , Parasite
Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 3.44±0.20μM. It exhibited significant activity against human leukemia cell lines HL60 and CEM. Tectol may cause itchy dermatiti...
T9014 SKI-178 Apoptosis , S1P Receptor
SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor with IC50 of 0.1-1.8 μM. It induces prolonged mitosis followed by apoptotic cell death through the intrinsic apoptotic cascade. The sustained activation of CDK1 during ...
T3131 Fosfomycin calcium Phosphomycin calcium salt,Fosmicin Antibacterial , Antibiotic
Fosfomycin calcium (Phosphomycin calcium salt) is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis.
T8262 Fosfomycin sodium Fosfomycin Disodium Antibacterial , Antibiotic
Fosfomycin sodium is a bactericidal, low-molecular weight, broad-spectrum antibiotic, with putative activity against several bacteria, including multidrug-resistant Gram-negative bacteria, by irreversibly inhibiting an e...
T8217 Enzalutamide carboxylic acid Androgen Receptor , Drug Metabolite
Enzalutamide carboxylic acid is an antagonist of androgen receptor (AR) .
T10981 DCZ0415 Apoptosis , Others , NF-κB
DCZ0415 induces antimyeloma activity in vitro, in vivo and in primary cells of drug-resistant myeloma patients. DCZ0415 is a potent TRIP13 inhibitor that can impair the repair of non-homologous end junctions and inhibit ...
T9830 GSK2556286 GSK286 Antibacterial
GSK2556286 (GSK286) is an orally active inhibitor of Mycobacterium tuberculosis (M. tuberculosis).GSK2556286 inhibits the growth of human macrophages with an IC50 value of 0.07 μM.GSK2556286 is effective against both mul...
T10378 Artelinic acid Others
Artelinic acid, a derivative of Artemisinin, is an antimalarial drug for the treatment of multidrug-resistant strains of Plasmodium falciparum.
T10356 AQ-13 dihydrochloride Parasite
AQ-13 dihydrochloride is an antimalarial drug. It is effective against drug-resistant strains of Plasmodium falciparum.
T64860 3-(Trifluoromethyl)cinnamic acid 3-(3-(Trifluoromethyl)phenyl)acrylic acid Antibiotic
3-(Trifluoromethyl)cinnamic acid (3-(3-(Trifluoromethyl)phenyl)acrylic acid) can be used to study drug-resistant bacterial infections.
T14081 Enmetazobactam AAI101 Antibacterial
Enmetazobactam (AAI101) is an extended-spectrum β-lactamase inhibitor for the treatment of multi-drug resistant gram-negative bacterial infections.
T22269 Benzyldodecyldimethylammonium Chloride Dihydrate Antibacterial
Benzyldodecyldimethylammonium chloride dihydrate can be used as an insecticide reagent. It can target drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, multidrug-resistant Pseudomonas aerugino...
T5315 TCA1 TCA-1,TCA 1 Antibacterial , Antibiotic
TCA1 (TCA 1) is a small molecule with activity against drug-resistant and persistent tuberculosis.
T73586 Anticonvulsant agent 2 Others
Anticonvulsant agent 2 is a potent orally active anticonvulsant that has shown antiepileptic activity in a model of drug-resistant epilepsy.
TQ0152 Dalfopristin RP54476 Antibacterial , Antibiotic
Dalfopristin (RP54476) is a semi-synthetic streptogramin antibiotic. Quinupristin/Dalfopristin (Q/D) is used for the treatment of multi-drug resistant Enterococcus faecium infections.
T6824 EAI045 EGFR
EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor.
T0391 Linezolid PNU-100766 MAO , Antibacterial , Antibiotic
Linezolid (PNU-100766), the first of the oxazolidinone class, is a synthetic antibiotic used for the therapy of infections resulted from multi-resistant bacteria including methicillin-resistant Staphylococcus aureus (MRS...
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