Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 of 3.44±0.20μM. It exhibited significant activity against human leukemia cell lines HL60 and CEM. Tectol may cause itchy dermatitis, the dermatitis appeared on the neck, upper legs, underarms, and trunk area.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 109.00 | |
5 mg | In stock | $ 268.00 | |
10 mg | In stock | $ 397.00 | |
25 mg | In stock | $ 663.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 297.00 |
Description | Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 of 3.44±0.20μM. It exhibited significant activity against human leukemia cell lines HL60 and CEM. Tectol may cause itchy dermatitis, the dermatitis appeared on the neck, upper legs, underarms, and trunk area. |
Targets&IC50 | FTase:3.44±0.20μM |
In vitro | Eleven known compounds and a new prenylated naphthoquinone, lippsidoquinone , were isolated from ethanol extracts of Lippia sidoides. Their structures were established by a combination of 1D and 2D NMR, IR, and EIMS spectral data analysis. The cytotoxic properties of compounds 3--13 were evaluated against HL60, SW1573, and CEM cell lines. Only Tectol and lippsidoquinone exhibited significant activity against human leukemia cell lines HL60 and CEM[1]. |
Source |
Molecular Weight | 450.52 |
Formula | C30H26O4 |
CAS No. | 24449-39-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/ml (122.08 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Tectol 24449-39-6 Metabolism Microbiology/Virology Transferase Parasite HL60 Ftase Inhibitor cell anti-malarial cytotoxic inhibit leukemia drug-resistant Farnesyl Transferase lines inhibitor