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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6455 | CP-91149 | Phosphorylase | |
CP-91149 is a selective glycogen phosphorylase (GP) inhibitor with IC50 of 0.13 μM in the presence of glucose, 5- to 10-fold less potent in the absence of glucose. | |||
T13230 | TXNIP-IN-1 | Others | |
TXNIP-IN-1 is an inhibitor of the TXNIP-TRX complex and used in the research of TXNIP-TRX complex associated metabolic disorder (diabetes), cardiovascular disease, or inflammatory disease. | |||
T7814 | Alloxan monohydrate | Proteasome | |
Alloxan Monohydrate is a glucose analog used to induce diabetes by destroying beta-cells. | |||
T13173 | TMPA | Others , AMPK | |
TMPA is a nuclear receptor Nur77 and LKB1 interaction antagonist. | |||
T21729 | (±)-Lisofylline | Others | |
(±)-Lisofylline is an enantiomer-specific, alkyl-substituted methylxanthine, which has specific and potent activity in down-regulating leukocyte activation. (±)-Lisofylline is an anti-inflammatory agent. | |||
T11845 | LGD-6972 | Glucagon Receptor | |
LGD-6972 is an antagonist of glucagon receptor. | |||
T5809 | Stachyose hydrate | Stachyose | Others |
Stachyose hydrate is a natual product,it highly promotes proliferation of lactic acid bacteria (LAB) by inducing LAB to produce more α-galactosidase to hydrolyze stachyose. | |||
T13867 | RH01386 | Others | |
RH01386 is a small molecule that can prevent ER stress-induced β cell dysfunction and death, and inhibits proapoptotic gene expression,has the potential for type 2 diabetes treatment. RH01386 restores ER stress-impaired ... | |||
T7544 | Fucoidan | Others | |
Fucoidan is found in various species of brown seaweed and algae,with anticancer, antiviral, neuroprotective, immune-modulating. | |||
T8982 | RH01687 | Others | |
RH01687 is a potent β-cell protector , exhibits β-cell-protective activities against endoplasmic reticulum (ER) stress. | |||
T2701 | GSK1292263 | GPR | |
GSK1292263 is a GPR119 agonist and has been investigated for the treatment of DIABETES MELLITUS, TYPE 2. | |||
T9987 | GSK3-IN-1 | GSK-3 | |
GSK3-IN-1 is a GSK3B-glycogen synthase kinase-3 beta inhibitor. | |||
T2042 | CTX-0294885 | Others | |
CTX-0294885, a novel bisanilino pyrimidine, exhibits inhibitory activity against a broad range of kinases in vitro and is further developed into a Sepharose-supported kinase capture reagent. | |||
TN1403 | Arjunolic acid | IL Receptor , TNF , Reactive Oxygen Species , JNK , AChE | |
Arjunolic acid has antioxidant, anti-inflammatory, antinociceptive and anticholinesterasic (AChE and BuChE) activities, it may as promising targets for the development of innovative multi-functional medicines for Alzheim... | |||
T8329 | AR 231453 | GPR | |
AR 231453 is a selective and orally available GPR119 agonist,can stimulate β-cell replication and improve islet graft function. | |||
TN1788 | Isookanin | Amylase | |
Isookanin shows strong diphenyl(2,4,6-trinitrophenyl)iminoazanium (DPPH) radical-scavenging activity with the IC50 value of 7.9 ± 0.53 μM. Isookanin is a potent inhibitor of α-amylase (IC50=0.447 mg/ml). | |||
T2210 | Genipin | (+)-Genipin | Others , Autophagy |
Genipin ((+)-Genipin), an active aglycone derived from an iridoid glycoside called geniposide, is found in the fruit of Gardenia jasminoides Ellis. | |||
T14779 | BRD7389 | SGK , FLT , Pim , CDK , S6 Kinase , DAPK | |
BRD7389 is an inhibitor of RSK family kinase with IC50s of 1.5 μM, 2.4 μM, and 1.2 μM for RSK1, RSK2, and RSK3, respectively. | |||
T3866 | Macelignan | Anwuligan,(+)-Anwulignan | Others , COX |
Macelignan (Anwuligan) is a lignan isolated from nutmeg with antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus species. | |||
TN1118 | Tormentic acid | Immunology/Inflammation related | |
Tormentic acid is a natural product. It has anticancer, anti-inflammatory, anti-atherogenic , anti-allodynic, and hepatoprotective properties, |