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Search Results for " diabetes "

20

Compounds

Cat No. Product Name Synonyms Targets
T6455 CP-91149 Phosphorylase
CP-91149 is a selective glycogen phosphorylase (GP) inhibitor with IC50 of 0.13 μM in the presence of glucose, 5- to 10-fold less potent in the absence of glucose.
T13230 TXNIP-IN-1 Others
TXNIP-IN-1 is an inhibitor of the TXNIP-TRX complex and used in the research of TXNIP-TRX complex associated metabolic disorder (diabetes), cardiovascular disease, or inflammatory disease.
T7814 Alloxan monohydrate Proteasome
Alloxan Monohydrate is a glucose analog used to induce diabetes by destroying beta-cells.
T13173 TMPA Others , AMPK
TMPA is a nuclear receptor Nur77 and LKB1 interaction antagonist.
T21729 (±)-Lisofylline Others
(±)-Lisofylline is an enantiomer-specific, alkyl-substituted methylxanthine, which has specific and potent activity in down-regulating leukocyte activation. (±)-Lisofylline is an anti-inflammatory agent.
T11845 LGD-6972 Glucagon Receptor
LGD-6972 is an antagonist of glucagon receptor.
T5809 Stachyose hydrate Stachyose Others
Stachyose hydrate is a natual product,it highly promotes proliferation of lactic acid bacteria (LAB) by inducing LAB to produce more α-galactosidase to hydrolyze stachyose.
T13867 RH01386 Others
RH01386 is a small molecule that can prevent ER stress-induced β cell dysfunction and death, and inhibits proapoptotic gene expression,has the potential for type 2 diabetes treatment. RH01386 restores ER stress-impaired ...
T7544 Fucoidan Others
Fucoidan is found in various species of brown seaweed and algae,with anticancer, antiviral, neuroprotective, immune-modulating.
T8982 RH01687 Others
RH01687 is a potent β-cell protector , exhibits β-cell-protective activities against endoplasmic reticulum (ER) stress.
T2701 GSK1292263 GPR
GSK1292263 is a GPR119 agonist and has been investigated for the treatment of DIABETES MELLITUS, TYPE 2.
T9987 GSK3-IN-1 GSK-3
GSK3-IN-1 is a GSK3B-glycogen synthase kinase-3 beta inhibitor.
T2042 CTX-0294885 Others
CTX-0294885, a novel bisanilino pyrimidine, exhibits inhibitory activity against a broad range of kinases in vitro and is further developed into a Sepharose-supported kinase capture reagent.
TN1403 Arjunolic acid IL Receptor , TNF , Reactive Oxygen Species , JNK , AChE
Arjunolic acid has antioxidant, anti-inflammatory, antinociceptive and anticholinesterasic (AChE and BuChE) activities, it may as promising targets for the development of innovative multi-functional medicines for Alzheim...
T8329 AR 231453 GPR
AR 231453 is a selective and orally available GPR119 agonist,can stimulate β-cell replication and improve islet graft function.
TN1788 Isookanin Amylase
Isookanin shows strong diphenyl(2,4,6-trinitrophenyl)iminoazanium (DPPH) radical-scavenging activity with the IC50 value of 7.9 ± 0.53 μM. Isookanin is a potent inhibitor of α-amylase (IC50=0.447 mg/ml).
T2210 Genipin (+)-Genipin Others , Autophagy
Genipin ((+)-Genipin), an active aglycone derived from an iridoid glycoside called geniposide, is found in the fruit of Gardenia jasminoides Ellis.
T14779 BRD7389 SGK , FLT , Pim , CDK , S6 Kinase , DAPK
BRD7389 is an inhibitor of RSK family kinase with IC50s of 1.5 μM, 2.4 μM, and 1.2 μM for RSK1, RSK2, and RSK3, respectively.
T3866 Macelignan Anwuligan,(+)-Anwulignan Others , COX
Macelignan (Anwuligan) is a lignan isolated from nutmeg with antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus species.
TN1118 Tormentic acid Immunology/Inflammation related
Tormentic acid is a natural product. It has anticancer, anti-inflammatory, anti-atherogenic , anti-allodynic, and hepatoprotective properties,
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TargetMol