Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TXNIP-IN-1 is an inhibitor of the TXNIP-TRX complex and used in the research of TXNIP-TRX complex associated metabolic disorder (diabetes), cardiovascular disease, or inflammatory disease.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 135.00 | |
5 mg | In stock | $ 289.00 | |
10 mg | In stock | $ 438.00 | |
25 mg | In stock | $ 726.00 | |
50 mg | In stock | $ 987.00 | |
100 mg | In stock | $ 1,380.00 | |
500 mg | In stock | $ 2,770.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 373.00 |
Description | TXNIP-IN-1 is an inhibitor of the TXNIP-TRX complex and used in the research of TXNIP-TRX complex associated metabolic disorder (diabetes), cardiovascular disease, or inflammatory disease. |
In vitro | TXNIP-IN-1 bocks high glucose (HG induced) TXNIP-TRX complex formation.In monocytes, TXNIP-IN-1 (1.25-5 μM) reduces HG-induced expression of TNF . In THP1 cells,TXNIP-IN-1 (1.25-5 μM; 72 hours) inhibits TXNIP mRNA expression . TXNIP-IN-1 (0.3-10 μM; 72 hours) inhibits TXNIP mRNA expression in murine RAW macrophages. In MIN6 cells, TXNIP-IN-1 (5-20 μM; 72 hours) decreases TXNIP but not TNF-alpha mRNA levels . TXNIP-IN-1 (0.62-5 μM; 72 hours) affects TXNIP and TNF-alpha mRNA expression in human pancreas 1.1B4 beta cells. TXNIP-IN-1 (5 μM; 16-72 hours) inhibits c-TRX interaction in THP1 cells cultured in 25mM glucose. TXNIP-IN-1 targets TXNIP mRNA in human pancreatic islets. |
Molecular Weight | 248.23 |
Formula | C12H12N2O4 |
CAS No. | 1268955-50-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (201.43 mM)
You can also refer to dose conversion for different animals. More
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TXNIP-IN-1 1268955-50-5 Others thioredoxin-interacting inhibit diabetes Inhibitor TRX TXNIP IN 1 protein TXNIP thioredoxin TXNIPIN1 inhibitor