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20

Compounds

Cat No. Product Name Synonyms Targets
T22518 5-BDBD P2X Receptor
5-BDBD is a potent and selective P2X4 receptor antagonist. 5-BDBD inhibits rP2X4R-mediated currents with an IC50 of 0.75 μM. 5-BDBD completely blocked the basal and acute hyperalgesia induced by NTG.
T10024 1-Octanol Octanol Calcium Channel , Endogenous Metabolite
1-Octanol, a saturated fatty alcohol, functions as an inhibitor of T-type calcium channels (T-channels), showing an inhibitory concentration (IC50) of 4 μM for native T-currents[1]. Additionally, 1-Octanol is recognized ...
T15555 IK1 inhibitor PA-6 Potassium Channel
IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1 (KIR2.x ion-channel-carried inward rectifier current)(IC50 of 12-15 nM for human and mouse KIR2.x currents).
T13619 Cloperastine fendizoate Hustazol EGFR
Cloperastine fendizoate (Hustazol) inhibits the hERG K+ currents in a concentration-dependent manner (IC50: 27 nM).
T21839L 10Panx Acetate 10Panx Acetate(955091-53-9 Free base) Others
10Panx Acetate is a mimetic inhibitory peptide that readily and reversibly inhibits the panx1 currents.
T30251 AZD-1305 UNII-CZO834LXQM,AZD 1305 Others
AZD-1305 is a novel anti-arrhythmic compound that primarily blocks the fast component of IKr, l-type calcium currents and intra-ward sodium currents in mammalian cells and ventricular cardiomyocytes and can be used in st...
T7579 1-BCP Piperonylic acid piperidide GluR , iGluR
1-BCP (Piperonylic acid piperidide) is a centrally active drug that modulates AMPA receptor gated currents.
T23782 Benzolamide CL-11366,W 1803,CL 11366,CL11366,W-1803 Carbonic Anhydrase
Benzolamide (CL 11366) inhibits carbonic anhydrase effectively and low-threshold calcium currents in hippocampal pyramidal neurons.
TQ0144 (S)-(-)-Bay-K-8644 (S)-(-)-Bay K 8644 Calcium Channel
(S)-(-)-Bay-K-8644 ((S)-(-)-Bay K 8644) is an agonist of L-type Ca2+ channel and activates Ba2+ currents with an EC50 of 32 nM.
T27205 DPI 201-106 DPI-201-106 Sodium Channel
DPI-201-106 is a cardioselective inhibitor of the TTX-resistant h1 Na channel inactivation. DPI-201-106 inhibits the L-type calcium current, and inward and delayed rectifier potassium currents.
T19839 Oxatomide Oxatomida P2X Receptor , Calcium Channel , 5-HT Receptor , Histamine Receptor
Oxatomide (Oxatomida) is a potent and orally active dual H1 histamine receptor and P2X7 receptor antagonist with antihistamine and antiallergic activity.Oxatomide can be used to block ATP-induced currents in the human P2...
T68123 Oxodipine Calcium Channel
Oxodipine, a dihydropyridine-type calcium antagonist , inhibited KCl-induced aortic contraction in rabbits and reduced cardiac force in less potent rat ventricular test-paper contractions. In rat cultured neonatal ventri...
T68055 Devapamil Devapamilo,Devapamilum Calcium Channel
Devapamil (Devapamilo) is a phenylalkylamine that blocks L-type calcium currents from the inner side of membrane cells in a use-dependent manner.
T4542 Clonixin Clonixic acid Others
Clonixin (Clonixic acid) is a non-steroidal anti-inflammatory drug (NSAID) with analgesic properties. This compound has been reported to block prostaglandin synthesis, and to block inward calcium currents.
T16964 SYM2206 SYM-2206,SYM 2206 Sodium Channel , iGluR
SYM2206 is a low affinity non-competitive AMPA receptor antagonist with an IC50 value of 1.6 μM.SYM2206 exhibits anticancer activity by blocking Nav1.6-mediated sustained currents and decreasing the survival of pancreati...
T14064 8-Bromo-cGMP sodium Calcium Channel , PKA
8-Bromo-cGMP sodium is a PKG activator, a membrane-permeable analog of cGMP. 8-Bromo-cGMP sodium has pain-relieving and vasodilatory effects, significantly inhibits Ca2+ macroscopic currents, and inhibits high K+-stimula...
T26822 Bisaramil hydrochloride RGH-2957,NK 1556,NK1556,Bisaramil,NK-1556,RGH 2957 Potassium Channel , Adrenergic Receptor
Bisaramil hydrochloride (Bisaramil) is a novel diazabicyclononane antiarrhythmic compound that inhibits the generation of free radicals.Bisaramil hydrochloride blocks sodium currents and inhibits the slow Ca(2+) action p...
T13164 Tipepidine hydrochloride Potassium Channel , Dopamine Receptor
Tipepidine hydrochloride is a reversible inhibitor of dopamine (DA) D2 receptor-mediated GIRK currents (IDA(GIRK)) (IC50: 7.0 μM), with antidepressant-like effect.
T12032 Mibefradil dihydrochloride Ro 40-5967 (dihydrochloride) Calcium Channel
Mibefradil dihydrochloride (Ro 40-5967 (dihydrochloride)) is an blocker of calcium channel with moderate selectivity for T-type Ca2+ channels (T-type and L-type currents with IC50s of 2.7 μM and 18.6 μM, respectively).
T16347 NS3623 Potassium Channel
NS3623 is an activator of human ether-a-go-go-related gene potassium channels. NS3623 has a dual mode of action, being an inhibitor of hERG1 channels. NS3623 activates the IKr and Ito currents and has an antiarrhythmic e...

Compounds

5-BDBD
T22518
Synonym:
Target: P2X Receptor
1-Octanol
T10024
Synonym: Octanol
Target: Calcium Channel, Endogenous Metabolite
IK1 inhibitor PA-6
T15555
Synonym:
Target: Potassium Channel
Cloperastine fendizoate
T13619
Synonym: Hustazol
Target: EGFR
10Panx Acetate
T21839L
Synonym: 10Panx Acetate(955091-53-9 Free base)
Target: Others
AZD-1305
T30251
Synonym: UNII-CZO834LXQM,AZD 1305
Target: Others
1-BCP
T7579
Synonym: Piperonylic acid piperidide
Target: GluR, iGluR
Benzolamide
T23782
Synonym: CL-11366,W 1803,CL 11366,CL11366,W-1803
Target: Carbonic Anhydrase
(S)-(-)-Bay-K-8644
TQ0144
Synonym: (S)-(-)-Bay K 8644
Target: Calcium Channel
DPI 201-106
T27205
Synonym: DPI-201-106
Target: Sodium Channel
Oxatomide
T19839
Synonym: Oxatomida
Target: P2X Receptor, Calcium Channel, 5-HT Receptor, Histamine Receptor
Oxodipine
T68123
Synonym:
Target: Calcium Channel
Devapamil
T68055
Synonym: Devapamilo,Devapamilum
Target: Calcium Channel
Clonixin
T4542
Synonym: Clonixic acid
Target: Others
SYM2206
T16964
Synonym: SYM-2206,SYM 2206
Target: Sodium Channel, iGluR
8-Bromo-cGMP sodium
T14064
Synonym:
Target: Calcium Channel, PKA
Bisaramil hydrochloride
T26822
Synonym: RGH-2957,NK 1556,NK1556,Bisaramil,NK-1556,RGH 2957
Target: Potassium Channel, Adrenergic Receptor
Tipepidine hydrochloride
T13164
Synonym:
Target: Potassium Channel, Dopamine Receptor
Mibefradil dihydrochloride
T12032
Synonym: Ro 40-5967 (dihydrochloride)
Target: Calcium Channel
NS3623
T16347
Synonym:
Target: Potassium Channel
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TargetMol