chalcone — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2S0961	Chalcone	benzylideneacetophenone,phenyl styryl ketone,Cinnamophenone,benzalacetophenone,β-phenylacrylophenone	EGFR , Antibacterial
	Chalcone (Cinnamophenone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones.		EGFR , Antibacterial
T3322	Trans-Chalcone	Chalcone,Cinnamophenone,Chalkone	Apoptosis , Others , Antifungal , Fatty Acid Synthase
	trans-Chalcone (Chalkone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones.		Apoptosis , Others , Antifungal , Fatty Acid Synthase
T10785	Chalcone 4 hydrate		Others , Parasite
	Chalcone 4 hydrate, an anti-parasite compound, inhibits the growth of Theileria and Babesia.		Others , Parasite
TN2083	Pinostrobin chalcone
	Pinostrobin chalcone, a chalcone analog isolated from the leguminous plant, Mucuna pruriens, exhibits anticancer activity with an IC50 value of 20.42±2.23 μg/mL against MDA-MB-231 and 22.51±0.42 μg/mL against the HT-29 c...
TN2078	Pinocembrin chalcone	2',4',6'-Trihydroxychalcone,Pinocembrinchalcone	Calcium Channel , Tyrosinase , Antibacterial , Antifection
	Pinocembrin chalcone is an inhibitor of tyrosinase with antimutagenic effects. Pinocembrin chalcone can be used in studies about the prevention of gastric ulcers.		Calcium Channel , Tyrosinase , Antibacterial , Antifection
T7784	Naringenin chalcone	Isosalipurpol,2',4,4',6'-TETRAHYDROXYCHALCONE,Chalcononaringenin,Chalconaringenin	Others
	Naringenin chalcone (Isosalipurpol) is a product natural isolated from stems of Machaerium isadelphum (Fabaceae).		Others
T2S2173	(E)-Naringenin chalcone	Isosalipurpol,Chalconaringenin,trans-2'4'6'4-tetrahydroxychalcone	Others
	Naringenin chalcone (Isosalipurpol) has antiallergic activity Naringenin chalcone suppresses asthmatic symptoms by inhibiting Th2 cytokine production from CD4 T cells. Naringenin chalcone is a potent tomato flavonoid tha...		Others
T24834	ß-Hydroxymethyl chalcone	Beta-Hydroxymethyl chalcone,Betahydroxymethyl chalcone,Beta Hydroxymethyl chalcone
	-Hydroxymethyl chalcone is the first selective Histone Deacetylase 2 inhibitor.
TN7224	2,2'-Dihydroxy chalcone		Antibacterial , Autophagy
	2,2'-Dihydroxy chalcone is a potent inhibitor of β-glucuronidase (IC50=1.6±0.2 μM) and lysozyme (IC50=1.4±0.2 μM) release from rat neutrophils stimulated with fMLP/CB.2,2'-Dihydroxy chalcone has inhibitory activity again...		Antibacterial , Autophagy
TN7226	2-Hydroxy-3-methoxy chalcone
	2-Hydroxy-3-methoxy chalcone has anticancer activity and inhibits colon cancer.
T6427	Butein	2’,3,4,4’-tetrahydroxy Chalcone	Apoptosis , EGFR , Others , PDE , Autophagy
	Butein (2’,3,4,4’-tetrahydroxy Chalcone), a plant polyphenol, is isolated from Rhus verniciflua. It can inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, and also can inhibit EGFR.		Apoptosis , EGFR , Others , PDE , Autophagy
TN3987	Eriodictyol chalcone		Anti-infection , Aromatase
	Eriodictyol chalcone has anti-plasmodial effects on P. falciparum growth.		Anti-infection , Aromatase
T2994	(E)-Cardamonin	Alpinetin chalcone,Cardamomin,Cardamonin,(E)-Cardamoni	Apoptosis , TRP/TRPV Channel
	(E)-Cardamonin (Alpinetin chalcone) is a chalconoid that has been isolated from several plants including Alpinia katsumadai and Alpinia conchigera. It is a novel antagonist of hTRPA1 cation channel with an IC50 of 454 nM...		Apoptosis , TRP/TRPV Channel
T32230	Isosalipurposide	Phlorizin chalcone
	Isosalipurposide, a chalcone compound, exerts a cytoprotective effect against oxidative injury via Nrf2 activation.
TN1895	Luteolinidin chloride		CD38
	Luteolinidin chloride is a natural product. It is a potent CD38 inhibitor which can protect the heart against I/R injury with preservation of eNOS function and prevention of endothelial dysfunction in vivo.		CD38
T38815	Millepachine		Apoptosis
	Millepachine is a natural product found in the Chinese herbal medicine with strong antitumor effects against numerous human cancer cells.		Apoptosis
T7917	4'-Hydroxychalcone	2-Benzal-4-Hydroxyacetophenone	Proteasome
	4'-Hydroxychalcone (2-Benzal-4-Hydroxyacetophenone) is a chalcone metabolite with hepatoprotective activity		Proteasome
T3S0737	Flavokawain A	Flavokavain A	Apoptosis , p38 MAPK
	NSC-37445 has anti-tumor activity, such as inhibits growth of bladder tumor cells in a nude mice model , prevents the recurrence and progression of non-muscle-invasive urothelial cell carcinoma. NSC-37445 can significant...		Apoptosis , p38 MAPK
T21854	Proteasome inhibitor IX	PS-IX,AM114	Proteasome
	Proteasome inhibitor IX (PS-IX) is an inhibitor of chymotrypsin-like activity of the 20S proteasome (IC50 ~1 μM). Proteasome inhibitor IX shows potent anticancer activity. Proteasome inhibitor IX exhibits HCT116 p53+/+ c...		Proteasome
T7432	2'-Hydroxy-2-methoxychalcone	2'-Hydroxy-2-methoxychalcone	Others , Antibacterial
	2'-Hydroxy-2-methoxychalcone is a synthetic chalcone with antibacterial activity.		Others , Antibacterial