Home Tools
Log in
Cart

Search Result

Search Results for " atherosclerotic "

20

Compounds

Cat No. Product Name Synonyms Targets
T15108 DG-041 Prostaglandin Receptor
DG-041 is an antagonist of high-affinity EP3 receptor (IC50s: 4.6 nM and 8.1 nM in the binding and FLIPR assay, respectively). DG-041 inhibits PGE2 facilitation of platelet aggregation and has the blood-brain barrier per...
T9920 Evolocumab Others
Evolocumab is a human IgG2 monoclonal antibody that binds to human PCSK9 Proprotein Convertase Subtilisin Kexin Type 9).
T23550 YM-750 YM 750 Acyltransferase
YM-750 is a potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), with an IC50 value of 0.18 μM. ACAT is an enzyme that catalyzes the conversion of cholesterol and long-chain fatty-acyl-coenzyme A into cholest...
T0686 Orlistat Ro-18-0647,Tetrahydrolipstatin Apoptosis , Others , Fatty Acid Synthase
Orlistat (Tetrahydrolipstatin) is an Intestinal Lipase Inhibitor. The mechanism of action of orlistat is as a Lipase Inhibitor.
T1781 GW9508 GW 9508 GPR , Potassium Channel
GW9508(GW 9508) is a potent and selective agonist for FFA1 (GPR40), stimulates insulin secretion in a glucose-sensitive manner.
T15757 Limaprost 17α,20-dimethyl-δ2-PGE1,OP1206,ONO1206 PGE Synthase
Limaprost (17α,20-dimethyl-δ2-PGE1) is an analog of PGE1 with structural modifications intended to give it a prolonged half-life and greater potency.It is a potent and orally active vasodilator. Limaprost increases blood...
T10063 LDL-IN-3 Antioxidant
LDL-IN-3 shows anti-atherosclerotic and antioxidant activities.
T2901 Daidzin NPI-031D,Daidzein 7-O-glucoside,Daidzoside,Daidzein 7-glucoside Dehydrogenase , Reverse Transcriptase , Mitochondrial Metabolism
Daidzin (Daidzoside) is an isoflavone isolated from soya bean with anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities.
T10584 Bovinic acid (9Z,11E)-Octadecadienoic acid,Rumenic acid Endogenous Metabolite
Bovinic acid ((9Z,11E)-Octadecadienoic acid) is a conjugated linoleic acid with anticancer and anti-atherosclerotic activity and can be used to study coronary heart disease and obesity in the elderly.
T12981 SP-8356 Autophagy
SP-8356 is a potent, orally active inhibitor of cluster of differentiation 147 (CD147),and is an anti-inflammatory synthetic verbenone derivative, with anti-atherosclerotic effects.
TN6951 Ethyl linoleate Others
Ethyl linoleate is a natural product.
TN1511 Cleomiscosin A LDL , Antioxidant , TNF
Cleomiscosin A is derived from Acer okamotoanum leaf and twig and shows inhibitory activity to TNF-α secretion of the mouse peritoneal macrophages. Cleomiscosin A can be used in studies about the prevention of LDL oxidat...
T5565 Undecanedioic acid Others , Endogenous Metabolite
Undecanedioic acid has been found in parts of human aortas with advanced atherosclerotic lesions associated with intercellular matrix macromolecules and specifically with elastin.
T30506 BMS-212122 UNII-0Z473OO6GB,BMS212122,BMS 212122 CETP
BMS-212122 (UNII-0Z473OO6GB) is a potent inhibitor of microsomal triglyceride transfer protein (MTP) and has shown hypolipidemic effects in animal studies.BMS-212122 significantly reduced lipid content and monocyte-deriv...
T8189 Dihydroberberine Potassium Channel , HSP , HER
Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities. It inhibits human ether-a-go-go-related gene (hERG) channels and remarkably reduces Hsp90 expression and its interacti...
T1082 Benzyl isothiocyanate Benzoylthiocarbimide,Isothiocyanic Acid Benzoyl Ester Apoptosis , Antibacterial , Antibiotic
Benzyl isothiocyanate (Benzoylthiocarbimide) (BITC) is an isothiocyanate originally found in cruciferous vegetables. It shows immunomodulatory, anti-parasitic, antibiotic, antioxidative, anti-atherosclerotic, anti-angiog...
T17157 TRAF-STOP inhibitor 6877002 CD40-TRAF6 inhibitor NF-κB
TRAF-STOP inhibitor 6877002 (CD40-TRAF6 inhibitor), is a selective inhibitor of CD40-TRAF6 interaction. TRAF-STOP 6877002 reduces leukocyte recruitment, and reduces macrophage activation; reduces macrophage proliferation...
T5244 Aminomalonic acid 2-Aminopropanedioic Acid,Aminomalonate Others , Endogenous Metabolite
Aminomalonic acid (Aminomalonate) (Ama) was first detected in alkaline hydrolysates of proteins in 1984. Ama has been isolated from proteins of Escherichia coli and human atherosclerotic plaque. The presence of Ama has i...
T3S0364 L-Arginine L-Arg,(S)-(+)-Arginine IL Receptor , Endogenous Metabolite , NO Synthase
1. L-Arginine (L-Arg) exhibits anti-atherosclerotic effect. 2. L-Arginine and soy enriched diet are effective in prevention of osteoporosis associated with diabetes mellitus. 3. Exogenous L-Arginine could enhance neonate...
T5280 3-Chloro-L-Tyrosine 3-Chlorotyrosine,Chlorotyrosine Others , Endogenous Metabolite
3-Chloro-L-Tyrosine (Chlorotyrosine), a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low-density lipoprotein isolated from human atherosclerotic intima. In particular, myeloperoxidase h...

Compounds

DG-041
T15108
Synonym:
Target: Prostaglandin Receptor
Evolocumab
T9920
Synonym:
Target: Others
YM-750
T23550
Synonym: YM 750
Target: Acyltransferase
Orlistat
T0686
Synonym: Ro-18-0647,Tetrahydrolipstatin
Target: Apoptosis, Others, Fatty Acid Synthase
GW9508
T1781
Synonym: GW 9508
Target: GPR, Potassium Channel
Limaprost
T15757
Synonym: 17α,20-dimethyl-δ2-PGE1,OP1206,ONO1206
Target: PGE Synthase
LDL-IN-3
T10063
Synonym:
Target: Antioxidant
Daidzin
T2901
Synonym: NPI-031D,Daidzein 7-O-glucoside,Daidzoside,Daidzein 7-glucoside
Target: Dehydrogenase, Reverse Transcriptase, Mitochondrial Metabolism
Bovinic acid
T10584
Synonym: (9Z,11E)-Octadecadienoic acid,Rumenic acid
Target: Endogenous Metabolite
SP-8356
T12981
Synonym:
Target: Autophagy
Ethyl linoleate
TN6951
Synonym:
Target: Others
Cleomiscosin A
TN1511
Synonym:
Target: LDL, Antioxidant, TNF
Undecanedioic acid
T5565
Synonym:
Target: Others, Endogenous Metabolite
BMS-212122
T30506
Synonym: UNII-0Z473OO6GB,BMS212122,BMS 212122
Target: CETP
Dihydroberberine
T8189
Synonym:
Target: Potassium Channel, HSP, HER
Benzyl isothiocyanate
T1082
Synonym: Benzoylthiocarbimide,Isothiocyanic Acid Benzoyl Ester
Target: Apoptosis, Antibacterial, Antibiotic
TRAF-STOP inhibitor 6877002
T17157
Synonym: CD40-TRAF6 inhibitor
Target: NF-κB
Aminomalonic acid
T5244
Synonym: 2-Aminopropanedioic Acid,Aminomalonate
Target: Others, Endogenous Metabolite
L-Arginine
T3S0364
Synonym: L-Arg,(S)-(+)-Arginine
Target: IL Receptor, Endogenous Metabolite, NO Synthase
3-Chloro-L-Tyrosine
T5280
Synonym: 3-Chlorotyrosine,Chlorotyrosine
Target: Others, Endogenous Metabolite
1 2 3
TargetMol