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Search Results for " anti-metastatic "

20

Compounds

Cat No. Product Name Synonyms Targets
T9582 CLEFMA NF-κB
CLEFMA has anti-proliferative activity. CLEFMA inhibits tumor growth associated with NF-κB-regulated anti-inflammatory and anti-metastatic effects.
T8310 MMP-9-IN-1 MMP
MMP-9-IN-1 is an inhibitor of specific matrix metalloproteinase-9 (MMP-9).
T5125 LY3200882 TGF-beta/Smad
LY3200882 is a highly selective inhibitor of TGF-β receptor type 1 (TGFβRI).
T5S0803 Columbamine Columbamin,Dehydroisocorypalmine Others
Columbamine (Columbamin) shows strong activity with IC5 48.1 μM.Columbamine exerts anti-proliferative and anti-vasculogenic effects on metastatic human osteosarcoma U2OS cells with low toxicity.
T17255 WJ460 Others
WJ460 is an effective inhibitor of myoferlin. WJ460 exerts anti-metastatic activity in breast cancer cells.
T26969 CCT365623 CCT-365623,CCT 365623 Monoamine Oxidase
CCT365623 is an orally bioavailable Lysyl Oxidase inhibitor with good anti-LOX potency, selectivity, pharmacokinetic properties, as well as anti-metastatic efficacy.
T9236 WSB1 Degrader 1 Others , E1/E2/E3 Enzyme
WSB1 Degrader 1 is a potent, orally active degrader of WD repeat and SOCS box-containing 1, exhibiting anti-cancer metastatic effects.
T62536 S100P-IN-1 Others
S100P-IN-1 is a potent S100P inhibitor.S100P-IN-1 has anti-metastatic effects on pancreatic cancer (pancreatic) cells.
T9075 BDP-13176 Others
BDP-13176 is a potent inhibitor of fascin 1(Kd of 90 nM and an IC50 of 240 nM). It has potential as an anti-metastatic agent
T7927 β-Ionone β-lonone Apoptosis , Others
β-Ionone (β-lonone) is an end-ring analog of β-carotenoids which widely distributed in fruit and vegetables,with anti-proliferative, anti-metastatic
T1082 Benzyl isothiocyanate Benzoylthiocarbimide,Isothiocyanic Acid Benzoyl Ester Apoptosis , Antibacterial , Antibiotic
Benzyl isothiocyanate (Benzoylthiocarbimide) (BITC) is an isothiocyanate originally found in cruciferous vegetables. It shows immunomodulatory, anti-parasitic, antibiotic, antioxidative, anti-atherosclerotic, anti-angiog...
T77374 Ontuxizumab MORAb-004 Others
Ontuxizumab (MORAb-004) is a monoclonal antibody targeting endomelanic acid with anti-tumor effects.Ontuxizumab is a potent IgG1/κ anti-endothelin (TEM-1 or CD248) monoclonal antibody for the treatment of metastatic mela...
T20578 Maclurin Fustic extract,Morintannic acid,NSC 83240 Free radical scavengers , Reactive Oxygen Species
Maclurin (NSC-83240) is a phenolic component of mulberry twigs, exerts anti-metastatic effects. Maclurin effectively protects against OH-induced damages to DNA and MSCs and can be used in studies about the prevention of ...
T76828 Sonepcizumab LT 1009 LPL Receptor
Sonepcizumab (LT 1009) is a fully humanized monoclonal antibody against S1P. Sonepcizumab has anti-cancer activity and can be used to study metastatic renal cell carcinoma (mRCC) to prevent eye scarring after glaucoma fi...
T76857 Anetumab Others
Anetumab is a novel fully human anti-mesothelin IgG1 antibody that is a naked antibody to Anetumab ravtansine.Anetumab can be used to synthesize the antibody-activated molecule coupling, Anetumab ravtansine.Anetumab can ...
T76750 Cemiplimab REGN-2810,SAR-439684 Others
Cemiplimab (Anti-Human PD-1) is a human monoclonal antibody against programmed cell death receptor 1 (PD-1) and a checkpoint inhibitor that blocks PD-1/PD-L1 mediated T-cell inhibition and can be used in metastatic cance...
T5S2358 Dehydrocorydaline Dehydrocorydalin,13-Methylpalmatine BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimeriz...
T5S0053 Coptisine Coptisin Indoleamine 2,3-Dioxygenase (IDO)
1. Coptisine (Coptisin) treatment increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2, 3-dioxygenase . 2. Coptisine treats myocardial I/R likely through suppressing myocardial ...
T60616 MPT0G211 HDAC
MPT0G211 is a highly selective and orally active HDAC6 inhibitor (IC50=0.291 nM) that has neuroprotective effects and has shown anti-metastatic activity in human breast cancer cells. MPT0G211 has 1,000 times more affinit...
T77434 Vopratelimab JTX 2011 Others
Vopratelimab (JTX-2011) is a selective humanized immunoglobulin G1-kappa monoclonal antibody that is a potent ICOS agonist. Vopratelimab has a high affinity for inducible T cell CO stimulating factors (ICOS), with an aff...
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