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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2S0342 | Armillarisin A | Others , Interleukin | |
Armillarisin A enhancing the role of macrophages, inhibiting bacteria growth, improving the protein metabolism, and regulating liver function. | |||
T22344 | Icatibant Acetate | Bradykinin Receptor | |
Icatibant Acetate, an antagonist of the bradykinin B2 receptor, is used in the treatment of hereditary angioedema. | |||
T35664 | Tetracosactide acetate | Others | |
Cosyntropin (acetate) stimulates the release of corticosteroids such as cortisol from the adrenal gland. | |||
T20615 | Olsalazine | Dipentium,Salicylic acid | Others |
Olsalazine (Dipentium), an anti-inflammatory drug, is used in the treatment of inflammatory bowel disease. It is also a novel DNA hypomethylating agent. | |||
T9377 | ASK1-IN-2 | Apoptosis , ASK , MAPK | |
ASK1-IN-2 is a potent and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 32.8 nM. ASK1-IN-2 can potentially be used as a therapeutic strategy for ulcerative colitis[1]. | |||
TN1084 | 1,3,5,8-Tetrahydroxyxanthone | Desmethylbellidifolin | Anti-infection |
1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Gentianella acuta. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity. Dimethylbellidifolin show... | |||
T22368 | Metyrosine | α-Methyltyrosine | COX |
Metyrosine (α-Methyltyrosine) is an antihypertensive drug and could be used as a tyrosine hydroxylase inhibitor.Metyrosine significantly inhibits high COX-2 activity. Metyrosine is a very effective agent for blood pressu... | |||
T4084 | Sibofimloc | VRT-1353385,Antibiotic-202,Antibiotic 202 | Antibacterial , Antibiotic |
Sibofimloc (Antibiotic-202), an antibiotic compound, is used in treating bacterial infections. | |||
T2718 | Palmatine chloride | Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase | |
Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties. | |||
T31964 | Glycolithocholic acid | Lithocholic acid glycine conjugate,Lithocholylglycine | Others |
Glycolithocholic acid (Lithocholic acid glycine conjugate) is a glycine conjugate of lithocholic acid. | |||
T5S0802 | Palmatine | Berbericinine,Burasaine | Indoleamine 2,3-Dioxygenase (IDO) , AChR , AChE , Aurora Kinase |
1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palmatine has been used in the treatment of jaundice, dysentery,... | |||
T4602 | Hydrocortisone hemisuccinate | Hydrocortisone 21-he,hydrocortisone 21-hemisuccinate*free acid,Hydrocortisone 21-hemisuccinate | Glucocorticoid Receptor , Others , Interleukin |
Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) is a corticosteroid used as an analytical and chromatography reagent. | |||
T3147 | Pyrrolidinedithiocarbamate ammonium | PDTC,Pyrrolidinedithiocarbamate,APDC,1-Pyrrolidinedithiocarboxylic acid ammonium salt,Ammonium pyrrolidinedithiocarbamate | NF-κB |
Pyrrolidinedithiocarbamate ammonium (1-Pyrrolidinedithiocarboxylic acid ammonium salt), a selective NF-κB inhibitor, inhibits translation of nitric oxide synthase mRNA to prevent induction. | |||
T35898 | Izencitinib | ||
Izencitinib (TD-1473) is an orally active, gut-restricted JAK inhibitor with non-selective properties. It is primarily employed in the investigation of ulcerative colitis [1]. | |||
T3620 | Solcitinib | GLPG-0778,GSK-2586184 | JAK |
Solcitinib (GLPG-0778) (GSK2586184, GLPG0778) is a JAK1 inhibitor. Solcitinib may be potentially used for the treatment of psoriasis, ulcerative colitis, and systemic lupus erythematosus. | |||
T1544 | Olsalazine disodium | Dipentum,Olsalazine Sodium | Others , COX , Antibacterial , Antibiotic |
Olsalazine disodium (Dipentum) is bioconverted to 5-aminosalicylic acid (5-ASA) in the colon and has anti-inflammatory activity in ulcerative colitis. | |||
T0036 | 18β-Glycyrrhetinic acid | Enoxolone,Glycyrrhetin | Dehydrogenase , Endogenous Metabolite |
18β-Glycyrrhetinic acid (Enoxolone) is the major bioactive component of Glycyrrhizae Radix and possesses anti-ulcerative, anti-inflammatory and antiproliferative properties. | |||
T9914 | Vedolizumab | Integrin | |
Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis. | |||
T70084 | Dersalazine | Dersalazine Free Base | IL Receptor , Platelet aggregation |
Dersalazine (Dersalazine Free Base), an inhibitor of platelet-activating factor, exerts intestinal anti-inflammatory activity in different rodent types of colitis by down-regulating IL-17 expression, with potential effic... | |||
T64334 | Glycolithocholic acid, sodium salt | Others | |
Glycolithocholic acid sodium salt, the sodium form of Glycolithocholic acid, is a glycine-conjugated secondary bile acid utilized in diagnosing ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH), and primary s... |