tyrphostin — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6711	Tyrphostin AG1296	Tyrphostin AG 1296,AG 1296	Apoptosis , FGFR , FLT , PDGFR , c-Kit
	Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.		Apoptosis , FGFR , FLT , PDGFR , c-Kit
T2479	Tyrphostin A9	Malonoben,Tyrphostin 9,SF 6847,AG 17,RG-50872	EGFR , VEGFR , Influenza Virus , PDGFR
	Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitor		EGFR , VEGFR , Influenza Virus , PDGFR
T4528	Tyrphostin AG 528	Tyrphostin B66,AG 528	EGFR
	Tyrphostin AG 528 (Tyrphostin B66) is an inhibitor of EGFR (IC50: 4.9 μM) and ErbB2 (IC50: 2.1 μM).		EGFR
T7649	Tyrphostin A1	AG9,Tyrphostin 1	EGFR , Interleukin
	Tyrphostin A1 (Tyrphostin 1) is an inhibitor of EGFR tyrosine kinase .		EGFR , Interleukin
T7101	Tyrphostin AG30	Tyrphostin AG30(AG30)	EGFR , Tyrosine Kinases
	Tyrphostin AG30 (AG30) (AG30) is a potent protein tyrosine kinases (PTK) inhibitor.		EGFR , Tyrosine Kinases
T21622	Tyrphostin A25	AG-82,Tyrphostin AG 82,RG-50875	EGFR , GPR
	Tyrphostin A25 (Tyrphostin AG 82) is a specific EGFR tyrosine kinase inhibitor and GPR35 agonist with an IC50 value of 0.94 μM for GPR35 and an EC50 value of 5.3 μM for GPR35.		EGFR , GPR
T2063	Tyrphostin 23	RG-50810,TX 825,Tyrphostin A23,AG18	EGFR
	Tyrphostin 23 (AG18) inhibits EGFR with IC50 of 35 μM.		EGFR
T13238	Tyrphostin AG1433	SU1433,AG1433	VEGFR , PDGFR
	Tyrphostin AG1433 (AG1433) is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM).		VEGFR , PDGFR
T34973	Tyrphostin 8	4-Hydroxybenzylidenemalononitrile	EGFR , GTPase
	Tyrphostin 8(4-Hydroxybenzylidenemalononitrile) is a potent GTPase inhibitor that inhibits EGFR kinase with an IC50 of 560 μM.Tyrphostin 8 inhibits protein serine/threonine calmodulin phosphatases (IC50=21 μM), enhances ...		EGFR , GTPase
T8534	Tyrphostin AG 112		EGFR
	Tyrphostin AG 112 is an inhibitor of EGFR phosphorylation.		EGFR
T6712	Tyrphostin AG 879	AG 879	Apoptosis , EGFR , Trk receptor , HER , PDGFR
	Tyrphostin AG 879 (AG 879) effectively inhibits HER2/ErbB2 (IC50: 1 μM), 100- and 500-fold higher selective to ErbB2 than EGFR and PDGFR.		Apoptosis , EGFR , Trk receptor , HER , PDGFR
T22450	Tyrphostin B44, (+) enantiomer		EGFR
	Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-) enantiomer.		EGFR
T67707	Tyrphostin AG 538	AG 538	IGF-1R
	Tyrphostin AG 538 is a chalcone compound, an IGF-1 receptor kinase inhibitor (IC₅0 : for 400 nM) that is potent, cell-permeable, reversible, and competitive.		IGF-1R
T11593	I-OMe-Tyrphostin AG 538	I-OMe-AG 538	IGF-1R , PI3K
	I-OMe-Tyrphostin AG 538 is a specific IGF-1R inhibitor and ATP-competitive inhibitor of PI5P4Kα (IC50: 1 µM).I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated signaling and exhibits preferential cytotoxicity to nutrient-d...		IGF-1R , PI3K
T24910	Tyrphostin A46	Tyrphostin A-46,Tyrphostin A 46
	Tyrphostin A46 is an antagonist of the epidermal growth factor-urogastrone receptor.
T24909	Tyrphostin 51	Tyrphostin A51,Tyrphostin A-51,Tyrphostin A 51
	Tyrphostin 51 is an effective inhibitor of EGFR kinase.
T4326	AG 555	Tyrphostin B46,Tyrphostin AG 555	EGFR , Reverse Transcriptase
	AG 555 (Tyrphostin B46) is an EGFR tyrosine kinase inhibitor.		EGFR , Reverse Transcriptase
T24912	Tyrphostin AG 568	Tyrphostin AG-568,Tyrphostin AG568
	Tyrphostin AG 568 promotes Tyrphostin-induced inhibition of p210bcr-abl tyrosine kinase activity. It also induces K562 to differentiate.
T24911	Tyrphostin AG 1112	Tyrphostin AG-1112,Tyrphostin AG1112
	Tyrphostin AG 1112 is a Bcr-Abl kinase blocker. It can activate the terminal differentiation of K562 cells and the purging of Ph+ cells.
T2693	AG1024	Tyrphostin AG 1024,Tyrphostin,AGS 200	Apoptosis , IGF-1R
	AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).		Apoptosis , IGF-1R