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Search Result

Search Results for " p11 "

Targets

Integrin

28

Compounds

1

Natural Products

7

Recombinant Proteins

Cat No. Product Name Synonyms Targets
TP1879L1 P11 acetate Integrin
P11 acetate is an integrin αvβ3-vitronectin interaction antagonist(IC50 = 2.74 nM).
TP2326L Oligopeptide P11-4 acetate(593266-60-5 free base) Others
Oligopeptide P11-4 acetate is a peptide
T34081 Piromelatine NEU-P-11,NEU-P 11,NEU-P11 P2X Receptor , 5-HT Receptor , MT Receptor , Sodium Channel , TRP/TRPV Channel
Piromelatine is an agonist of melatonin MT1/MT2 receptors, 5-HT1A and 5-HT1D, and an antagonist of 5-HT2B.Piromelatine has antinociceptive activity with inhibitory effects on P2X3, TRPV1, and Nav1.7 channels, and can be ...
TP1879 HSDVHK-NH2 P11
Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.
T24586 PAFAH1b2 PAFAH-1-b-2,3-IN-P11,3INP11,3 IN P11,PAFAH 1 b 2
PAFAH1b2 is a selective platelet-activating factor acetylhydrolases 1b2 and 1b3 inhibitor that acts by impairing cancer cell survival.
T10922 CYP11B2-IN-1 P450
CYP11B2-IN-1 is an effective and selective inhibitor of CYP11B2 with IC50s of 2.3 nM and 142 nM for CYP11B2 and CYP11B1.
TP1947L P110 TFA Others
P110 TFA is a dynamin-related protein 1 (Drp1) inhibitor, inhibits Drp1 GTPase activity.
T16422 P110δ-IN-1 PWT-143 PI3K
P110δ-IN-1 (PWT-143) is an effective and selective inhibitor of P110δ (IC50: 8.4 nM).
T3969 I-CBP112 Epigenetic Reader Domain , Histone Acetyltransferase
I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor targeting the CBP/p300 bromodomains.
T7334 NP118809 39-1B4 Calcium Channel
NP118809 (39-1B4) is a potent N-type calcium channel blocker(IC50 : 0.11 μM).
T9596 AP1189 acetate Melanocortin Receptor
AP1189 acetate is a biased agonist at melanocortin 1 and melanocortin 3 receptors.
T4247 I-CBP112 hydrochloride Epigenetic Reader Domain
I-CBP112 is a selective inhibitor of the bromodomain-containing transcription factors. I-CBP112 (1 mM) has little activity against other bromodomains. I-CBP112 targets the CBP/p300 bromodomains. I-CBP112 significantly re...
T4472 NMS-P118 PARP
NMS-P118 is a potent, selective and orally available Inhibitor of PARP-1 for cancer therapy.
T24437 MCP110 MCP-110,MCP 110 Raf , Ras
MCP110 is an inhibitor of the interaction of Ras with Raf-1 and can be used in studies about the treatment of human tumors.
T64249 CYP11B1-IN-2
CYP11B1-IN-2 (compound 7aa) is a selective, orally active inhibitor of CYP11B1 that acts on human CYP11B1 (IC50: 9 nM) and rat CYP11B1 (IC50: 25 nM). CYP11B1-IN-2 can be used to study diseases caused by cortisol overload...
T72397 PARP11 inhibitor ITK7 ITK7
PARP11 Inhibitor ITK7 (ITK7) is a potent, selective inhibitor of PARP11, demonstrating significant efficacy with an IC50 value of 14 nM. It is primarily utilized in research focused on cellular localization.
T78033 SDP116
SDP116, a synthetic peptide derivative of the GPR116 Stachel sequence, exhibits ADGRF5 agonistic activity [1].
T68254 WP1193
WP1193 is an inhibitor of the JAK2/STAT3 pathway.
T38005 P11149
P11149, a derivative of Galanthamine, acts as a competitive, orally active, and selective AChE inhibitor with the ability to weakly penetrate the blood-brain barrier (BBB). It demonstrates selective inhibition, exhibitin...
T78204 CYP11A1-IN-1
CYP11A1-IN-1 (compound 30) is a selective inhibitor of the enzyme CYP11A1, displaying an IC50 ranging from 201-2000 nM. It is applicable in the study of steroid receptor-mediated diseases, specifically targeting the andr...
T40850 [D-Trp11]-Neurotensin [D-Trp11]-Neurotensin
[D-Trp11]-Neurotensin is a compound that functions as a selective antagonist of Neurotensin (NT) in perfused rat hearts, while exhibiting full agonist properties in guinea pig atria and rat stomach strips. Additionally, ...
T80291 PP113
PP113 is an antimicrobial peptide with activity against both Gram-negative and Gram-positive bacteria, exhibiting minimum inhibitory concentrations (MICs) of 73.3 µM for E. coli, 23.3 µM for B. subtilis, 13 µM for S. aur...
T14940 CGP11952 Others
CGP11952 is same the benzodiazepines in its pharmacological action and it also is an experimental benzodiazepine derivative.
T15783 LP117 Others
LP117 is a novel and effective inhibitor of 5-Lipoxygenase (5-LO) product synthesis (IC50: 1.1 μM).
T61329 HP1142
HP1142 is a highly effective and specific inhibitor targeting the FLT3 receptor tyrosine kinase, with a particular affinity for its mutant variant FLT3/ITD. It exhibits a benzoimidazole scaffold-based structure, making i...
T10387 ASP1126 Others
ASP1126 is a selective and orally active sphingosine-1-phosphate (S1P) agonist (EC50s: 7.12 nM, 517 nM for hS1P1 and hS1P3).
T23491 UBP1112 Others
group III mGlu receptor antagonist
TP1947 P110
Dynamin-related protein 1 (Drp1) inhibitor, inhibits Drp1 GTPase activity. Displays no effect on dynamin 1 or other mitochondrial dynamics-related proteins. Inhibits mitochondrial fission, dysfunction and reactive oxygen...
Cat No. Product Name Synonyms Targets
T19328 Fructo-oligosaccharide DP11/GF10 Others
Fructo-oligosaccharide DP11/GF10 is a fructooligosaccharide (FOS) compound with a degree of polymerization (DP) equal to 11. FOS consists of 10 fructose units connected by (2→1)-β-glycosidic bonds, with a single D-glucos...

Natural Products

Fructo-oligosaccharide DP11/GF10
T19328
Synonym:
Target: Others

Recombinant Proteins

Species：
Human (6)
Mouse (1)
Expression System：
E. coli (5)
Baculovirus Insect Cells (1)
HEK293 Cells (1)
Tag：
N-6xHis-SUMO (2)
C-mFc (1)
His, GST (1)
N-10xHis (1)
N-6xHis (1)
N-His (1)
Cat No. Product Name Species Expression System
TMPY-01926 S100A10 Protein, Human, Recombinant (His) Human E. coli
S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that...
TMPH-01879 PARP11 Protein, Human, Recombinant (His) Human E. coli
Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins. Plays a role in nuclear envelope stability and nuclear remodeling during spermiogenesis. PARP11 Protein, Human, Recombinant (His) is exp...
TMPH-01181 CYP11B2 Protein, Human, Recombinant (His & SUMO) Human E. coli
CYP11B2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-01084 CYP11A1 Protein, Human, Recombinant (His & SUMO) Human E. coli
CYP11A1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 72.1 kDa and the accession number is P05108.
TMPY-00510 FKBP11 Protein, Human, Recombinant (mFc) Human HEK293 Cells
FKBP11 serve as biomarker and/or therapeutic target for Acute aortic dissection (AAD). FKBP11 during the development of HCC and FKBP11 has the potential to be an early marker for HCC.
TMPH-02775 Mup11 Protein, Mouse, Recombinant (His) Mouse E. coli
Mup11 Protein, Mouse, Recombinant (His) is expressed in E. coli.
TMPY-03455 FGFR1OP Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
FOP( fibroblast growth factor receptor 1 oncogene partner) is a largely hydrophilic protein postulated to be a leucine-rich protein family member. FOP contains 1 LisH domain. A t(6;8)(q27;p11) chromosomal translocati...
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