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MCP110

MCP110
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MCP110

Catalog No. T24437Cas No. 521310-51-0
MCP110 is an inhibitor of the interaction of Ras with Raf-1 and can be used in studies about the treatment of human tumors.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePrice/USDAvailabilityQuantity
1 mg$67In Stock
5 mg$163In Stock
10 mg$287In Stock
25 mg$511In Stock
50 mg$742In Stock
100 mg$987In Stock
500 mg$1,980In Stock
1 mL x 10 mM (in DMSO)$183In Stock
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Product Introduction

Bioactivity
Description
MCP110 is an inhibitor of the interaction of Ras with Raf-1 and can be used in studies about the treatment of human tumors.
In vitro
In A549 cells, MCP110 (20 μM) decreases Ras stimulation of Raf-1 and cyclin D level stimulated by the treatment with EGF (100 ng/mL), platelet-derived growth factor (20 ng/mL), and serum. In in HEK293 cells, MCP110 (10 and 20 μM) inhibits H-Ras (V12)-induced AP-1 activation. In fibrosarcoma HT1080 cells, MCP110 (1, 2, 5, 10, and 20 μM) shows a dose-dependent inhibition of elevated Raf-1 activity[1].
AliasMCP-110, MCP 110
Chemical Properties
Molecular Weight508.65
FormulaC33H36N2O3
Cas No.521310-51-0
Storage & Solubility Information
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 245 mg/mL (481.67 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9660 mL9.8299 mL19.6599 mL98.2994 mL
5 mM0.3932 mL1.9660 mL3.9320 mL19.6599 mL
10 mM0.1966 mL0.9830 mL1.9660 mL9.8299 mL
20 mM0.0983 mL0.4915 mL0.9830 mL4.9150 mL
50 mM0.0393 mL0.1966 mL0.3932 mL1.9660 mL
100 mM0.0197 mL0.0983 mL0.1966 mL0.9830 mL

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