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HSDVHK-NH2

Catalog No. TP1879 CAS 848644-86-0

Synonyms: P11

Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.

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HSDVHK-NH2, CAS 848644-86-0

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1 mg	Inquiry	$ 71.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.

Synonyms	P11
Molecular Weight	720.78
Formula	C30H48N12O9
CAS No.	848644-86-0

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 2 mg/mL

References and Literature

1. Lee et al (2004) High-throughput screening of novel peptide inhibitors of an integrin receptor from the hexapeptide library by using a protein microarray chip. J.Biomol.Screen. 9 687 PMID: 2. Choi et al (2010) Site-specific inhibition of integrin alpha v beta 3-vitronectin association by a ser-asp-val sequence through an Arg-Gly-Asp-binding site of the integrin. Proteomics 10 72 PMID: 3. Bang et al (2011) Pharmacoproteomic analysis of a novel cell-permeable inhibitor of tumor-induced angiogenesis. Mol.Cell Proteomics 10 M110 PMID:

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

HSDVHK-NH2 848644-86-0 HSDVHKNH2 HSDVHK NH2 P-11 HSDVHK-NH-2 P11 P 11 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.