mci — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T79260	MCI		Reactive Oxygen Species
	MCI, a chemical compound demonstrating significant anti-inflammatory effects, particularly in collagen-induced arthritis (CIA) models, modulates inflammation through macrophage reprogramming by enhancing ROS scavenging a...		Reactive Oxygen Species
T8443	MCI-225		Norepinephrine
	MCI-225 is a selective inhibitor of NA reuptake with 5-HT3 receptor antagonism.		Norepinephrine
T0407	Edaravone	MCI-186	Apoptosis , MMP , Free radical scavengers
	Edaravone (MCI-186)(MCI-186) is a potent new free radical scavenger used for the therapy of patients with acute brain infarction.		Apoptosis , MMP , Free radical scavengers
T4978	Sarpogrelate hydrochloride	MCI-9042	5-HT Receptor
	Sarpogrelate hydrochloride (MCI-9042) , a selective 5-HT2 antagonist, has been widely used as an anti-platelet agent for the treatment of PAD. Target: 5-HT2 Recepter Sarpogrelate is a drug which acts as an antagonist at ...		5-HT Receptor
T0155	Argatroban	MCI-9038,MD-805,Argipidine	Thrombin
	Argatroban (MCI-9038), a specific thrombin inhibitor, which is a non-heparin anticoagulant, prevents the formation of thrombi.		Thrombin
T71574	Mci 176
	Mci 176 is a quinazolinone calcium antagonist.
T28270	Osemozotan HCl	Osemozotan hydrochloride,MN-305,MCI-242,MKC-242,MKC242,MCI242
	Osemozotan is a 5-HT1A receptor agonist potentially for the treatment of generalized anxiety disorder.
T8443L	MCI-225 hydrochloride hydrate	AA-10021,AA10021,MCI225,DDP-225,AA-10025,AA-10026
	MCI-225 is a norepinephrine reuptake/5-HT3/5-HT reuptake inhibitor. MCI-225 could be effective in the treatment of senile dementia of the Alzheimer type, which is accompanied with both deficit in the BF-cortex cholinergi...
T16026	MCI826		P-gp , LTR
	MCI826 is a potent and selective antagonist of P-glycoprotein (P-gp) and peptide leukotrienes (p-LTs), showing anti-asthmatic activity in a guinea pig model of advanced asthma.		P-gp , LTR
T28752	Senazodan hydrochloride	Senazodan HCl,MCI-154,MCI154,MCI 154
	Senazodan HCl, a phosphodiesterase inhibitor, is used potentially for the treatment of heart failure.
T11152	Edaravone-d5	MCI-186 D5	Others
	Edaravone, a novel and potent free radical scavenger, effectively prevents MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator. Its deuterium-labeled variant, Edaravone D5, retains the origin...		Others
T82695	Colestilan	MCI-196,Colestimide
	Colestilan (MCI-196), a non-absorbable, non-calcium-based phosphate binder and anion exchange resin, exhibits oral activity and is utilized in the study of hypercholesterolemia [1] [2].
T22605	Bifemelane hydrochloride		MAO , Monoamine Oxidase
	Bifemelane hydrochloride is a MAO inhibitor		MAO , Monoamine Oxidase
T22246	Argatroban Monohydrate		Thrombin
	Argatroban Monohydrate is a specific thrombin inhibitor, which is a non-heparin anticoagulant, prevents the formation of thrombi.		Thrombin
T71572	HOE-K86-4321
	HOE-K86-4321 is a Bradykinin antagonist.
T76788	Demcizumab	OMP 21M18	Gamma-secretase
	Demcizumab (OMP 21M18) is an anti-DLL4 monoclonal antibody. Demcizumab is a potent Notch pathway inhibitor. Demcizumab is effective in multiple cancer models, both alone and in combination with chemotherapy agents.		Gamma-secretase
T15378L	Gemcitabine elaidate hydrochloride	CO-101 hydrochloride,Gemcitabine elaidate hydrochloride(210829-30-4(free base)),Gemcitabine 5'-elaidate hydrochloride,CP-4126 hydrochloride	Others
	Gemcitabine elaidate (CP-4126) hydrochloride is lipophilic pro-drug of Gemcitabine. Gemcitabine elaidate hydrochloride is converted to Gemcitabine by esterases in order to be phosphorylated. In contrast to gemcitabine, G...		Others
T0798	Triamcinolone	Fluoxyprednisolone,Aristocort,Rodinolone	Glucocorticoid Receptor , COX
	Triamcinolone (Aristocort) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. Upon cell entry, triamcinolone binds to and activates the glucocorticoid receptor, which leads to transloca...		Glucocorticoid Receptor , COX
T0251	Gemcitabine	NSC 613327,LY188011	Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Autophagy
	Gemcitabine (LY188011) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis. Gemcitabine has antitumor and antimetabolic activities. Gemcitabine induces autophagy and apoptosis.
T0820	Triamcinolone acetonide	Aristogel,Azmacort,Aristoderm	Glucocorticoid Receptor
	Triamcinolone acetonide (Azmacort) is a Corticosteroid. The mechanism of action of triamcinolone acetonide is as a Corticosteroid Hormone Receptor Agonist. It is an anti-inflammatory glucocorticoid used topically in the ...		Glucocorticoid Receptor