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MCI-225 hydrochloride hydrate

Catalog No. T8443L CAS 476148-82-0

Synonyms: AA-10021, AA10021, MCI225, DDP-225, AA-10025, AA-10026

MCI-225 is a norepinephrine reuptake/5-HT3/5-HT reuptake inhibitor. MCI-225 could be effective in the treatment of senile dementia of the Alzheimer type, which is accompanied with both deficit in the BF-cortex cholinergic neuron and cerebral glucose hypometabolism. MCI-225 enhances attentional eye tracking in midpontine pretrigeminal preparation.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

MCI-225 hydrochloride hydrate Chemical Structure

MCI-225 hydrochloride hydrate, CAS 476148-82-0

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	AA-10021, AA10021, MCI225, DDP-225, AA-10025, AA-10026
Molecular Weight	382.88
Formula	C17H20ClFN4OS
CAS No.	476148-82-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Eguchi J, Inomata Y, Saito K. The anxiolytic-like effect of MCI-225, a selective NA reuptake inhibitor with 5-HT3 receptor antagonism. Pharmacol Biochem Behav. 2001 Apr;68(4):677-83. PubMed PMID: 11526964. 2. Ishigooka J. [Serotonin-noradrenaline reuptake inhibitors(SNRIs)]. Nihon Rinsho. 2001 Aug;59(8):1523-9. Review. Japanese. PubMed PMID: 11519152. 3. Wu YL, Yoshida M, Emoto H, Ishii H, Koga K, Tanaka M. Effects of acute and chronic administration of MCI-225, a new selective noradrenaline reuptake inhibitor with 5-HT3 receptor blocking action, on extracellular noradrenaline levels in the hypothalamus of stressed rats. Jpn J Pharmacol. 2000 May;83(1):31-8. PubMed PMID: 10887938. 4. MCI 225. Drugs R D. 1999 Jul;2(1):51-2. PubMed PMID: 10610283.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

MCI-225 hydrochloride hydrate 476148-82-0 AA-10021 AA10021 AA 10025 MCI-225 AA 10026 MCI225 DDP-225 MCI-225 hydrochloride Hydrate AA-10025 AA 10021 MCI 225 hydrochloride hydrate MCI225 hydrochloride hydrate AA-10026 DDP225 AA10026 MCI 225 AA10025 DDP 225 inhibitor inhibit

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